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Clenbuterol

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Identification
Molecular formula
C12H18ClN5O
CAS number
37148-27-9
IUPAC name
1-(4-chlorophenyl)-2-[4-[2-(diethylamino)ethylamino]-6-methyl-pyrimidin-2-yl]guanidine
State
State
Clenbuterol is typically a solid at room temperature. It may also be available in various pharmaceutical preparations for application as needed.
Melting point (Celsius)
174.00
Melting point (Kelvin)
447.15
Boiling point (Celsius)
298.00
Boiling point (Kelvin)
571.15
General information
Molecular weight
277.19g/mol
Molar mass
277.1930g/mol
Density
1.0004g/cm3
Appearence

Clenbuterol typically appears as a solid. It may be available in the form of a white or off-white crystalline powder that is soluble in ethanol and slightly soluble in water. Its appearance can vary slightly based on formulation and purity.

Comment on solubility

Solubility of 1-(4-chlorophenyl)-2-[4-[2-(diethylamino)ethylamino]-6-methyl-pyrimidin-2-yl]guanidine

The solubility of 1-(4-chlorophenyl)-2-[4-[2-(diethylamino)ethylamino]-6-methyl-pyrimidin-2-yl]guanidine can be a complex subject due to its unique chemical structure. Understanding its solubility is essential for applications in medicinal chemistry and pharmacology.

Key Factors Influencing Solubility:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents.
  • Hydrogen Bonding: The ability to form hydrogen bonds may facilitate solubility in protic solvents, while lack thereof might hinder solubility.
  • Molecular Weight: Higher molecular weights may generally lead to lower solubility; however, this can vary significantly in complex molecules.
  • pH Sensitivity: Being a guanidine compound, solubility may be influenced by the pH of the solution, affecting its ionization state.

This compound is expected to exhibit moderate solubility in organic solvents and possibly lower solubility in water. Experimental data is often necessary to accurately characterize the solubility profile, but it may be predicted that:

  • It could be soluble in dimethyl sulfoxide (DMSO) or ethanol.
  • It may show poor solubility in aqueous environments due to large hydrophobic portions in its structure.

In practical applications, these solubility characteristics must be considered to optimize formulation and delivery in pharmaceutical contexts.

Interesting facts

Interesting Facts about 1-(4-chlorophenyl)-2-[4-[2-(diethylamino)ethylamino]-6-methyl-pyrimidin-2-yl]guanidine

This compound, known for its complex structure and diverse applications, is a fascinating example of medicinal chemistry in action. Here are some noteworthy points:

  • Pharmacological Use: This compound belongs to a class of medications that have been investigated for their role in treating various conditions, including hypertension and other cardiovascular issues.
  • Mechanism of Action: Its efficacy is largely attributed to its ability to influence specific pathways in the body, notably through its interaction with adrenergic receptors.
  • Structural Highlights: The presence of a chlorophenyl group and a pyrimidinyl moiety adds significant complexity and may enhance the compound's binding affinity at receptor sites.
  • Pharmaceutical Development: As a part of ongoing research, derivatives of this compound have been synthesized and evaluated to optimize therapeutic effects while minimizing side effects.
  • Research Potential: Its unique chemical structure suggests potential applications beyond simply cardiovascular treatment, opening avenues for research into areas such as cancer therapy or neuropharmacology.

In summary, 1-(4-chlorophenyl)-2-[4-[2-(diethylamino)ethylamino]-6-methyl-pyrimidin-2-yl]guanidine showcases the intriguing relationship between chemical structure and biological activity. As researchers continue to explore its properties, we may unlock new pathways for medical advances and improved patient outcomes.