Clonidine hydrochloride | Solubility of Things

Identification

Molecular formula

C₉H₉Cl₂N₅

CAS number

4205-90-7

IUPAC name

1-(4-chlorophenyl)-2-(4-methylpiperazin-4-ium-1-yl)imino-ethanone;chloride

State

At room temperature, clonidine hydrochloride is in a solid state. It tends to absorb moisture when exposed to air.

Melting point (Celsius)

275.00

Melting point (Kelvin)

548.00

Boiling point (Celsius)

301.20

Boiling point (Kelvin)

574.40

General information

Molecular weight

266.58g/mol

Molar mass

266.5800g/mol

Density

0.9891g/cm³

Appearence

Clonidine hydrochloride appears as a white to off-white crystalline powder. It is soluble in water and alcohol, which makes it suitable for both oral and parenteral administration.

Comment on solubility

Solubility of 1-(4-chlorophenyl)-2-(4-methylpiperazin-4-ium-1-yl)imino-ethanone;chloride

The solubility of the compound 1-(4-chlorophenyl)-2-(4-methylpiperazin-4-ium-1-yl)imino-ethanone;chloride can be influenced by various factors. This compound, with the chemical formula often associated with ionic constituents due to the presence of the chloride ion, is expected to exhibit good solubility in polar solvents. Here are some key points regarding its solubility:

General Behavior: As a quaternary ammonium compound, it tends to be soluble in water and other polar solvents.
Impact of Chloride Ion: The chloride ion can enhance water solubility, contributing to the ionic nature of the compound.
Organic Solvents: It may also dissolve in polar organic solvents such as methanol or ethanol, although the solubility can vary.
Temperature Dependence: Solubility might increase with temperature, making heating a useful method for enhancing dissolution.

In summary, the solubility characteristics of 1-(4-chlorophenyl)-2-(4-methylpiperazin-4-ium-1-yl)imino-ethanone;chloride can be described as generally favorable in polar media, which is crucial for potential applications in various chemical and pharmaceutical contexts.

Interesting facts

Interesting Facts about 1-(4-chlorophenyl)-2-(4-methylpiperazin-4-ium-1-yl)imino-ethanone; chloride

1-(4-chlorophenyl)-2-(4-methylpiperazin-4-ium-1-yl)imino-ethanone; chloride is a fascinating compound with significant implications in various fields, especially in medicinal chemistry. Here are some intriguing aspects of this compound:

Pharmacological Potential: This compound belongs to a category of chemical agents that have demonstrated potential as antipsychotic or antidepressant medications. Its ability to modulate neurotransmitter systems makes it a subject of interest for developing new therapeutic agents.
Chemical Structure: The compound features a unique structure that includes:

A chlorophenyl group, which is known for enhancing biological activity.
A methylpiperazine moiety, playing a critical role in improving the solubility and bioavailability of drugs.

Research Applications: In laboratory settings, this compound can serve as a model for studying receptor interactions and investigating the mechanism of action of similar drugs.
Innovative Synthesis: The chemical synthesis of this compound often involves advanced organo-metallic reactions, showcasing the creativity and complexity that can emerge in drug design.
Safety and Toxicology: As with many compounds that interact with biological systems, understanding the pharmacokinetics and toxicology of this compound is vital. Researchers often conduct extensive studies to assess its safety profile.

This compound exemplifies the intersection between chemistry and medicine, highlighting the ongoing efforts to develop new therapies. As research continues, the potential applications of 1-(4-chlorophenyl)-2-(4-methylpiperazin-4-ium-1-yl)imino-ethanone; chloride may expand, making it a compound worth watching in the scientific community.