Skip to main content

4-Chloroamphetamine

ADVERTISEMENT
Identification
Molecular formula
C10H12ClNO
CAS number
74698-16-3
IUPAC name
1-(4-chlorophenyl)-2-(ethylamino)propan-1-one
State
State

4-Chloroamphetamine exists as a solid at room temperature. It is often found in the form of a crystalline powder.

Melting point (Celsius)
146.00
Melting point (Kelvin)
419.15
Boiling point (Celsius)
259.00
Boiling point (Kelvin)
532.15
General information
Molecular weight
197.66g/mol
Molar mass
197.6610g/mol
Density
1.1780g/cm3
Appearence

4-Chloroamphetamine typically appears as a crystalline powder.

Comment on solubility

Solubility of 1-(4-chlorophenyl)-2-(ethylamino)propan-1-one

The solubility of 1-(4-chlorophenyl)-2-(ethylamino)propan-1-one, also known as ethylphenidate, can be complex due to its organic nature and structural characteristics. Generally, the solubility of organic compounds is influenced by factors such as polarity, molecular weight, and the presence of functional groups. Here’s what we know:

  • Polarity: This compound exhibits moderate polarity, attributed mainly to the ethylamino functional group, which influences its ability to interact with solvents.
  • Solvent Compatibility: It is expected to be soluble in organic solvents such as ethanol and dichloromethane, while having limited solubility in water due to its hydrophobic phenyl group.
  • Molecular Weight: With a moderate molecular weight, solubility can be enhanced in non-polar solvents compared to polar solvents.

In practical scenarios, measuring solubility can involve assessing the compound's behavior in various solvents at controlled temperatures. For researchers, understanding the solubility profile is crucial for applications involving formulation, pharmacokinetics, and synthesis. Thus, one might conclude that while 1-(4-chlorophenyl)-2-(ethylamino)propan-1-one has its limitations in aqueous solubility, it shows promise in more hydrocarbon or organic environments.

Interesting facts

Interesting Facts about 1-(4-chlorophenyl)-2-(ethylamino)propan-1-one

1-(4-chlorophenyl)-2-(ethylamino)propan-1-one, often referred to in scientific literature by its abbreviated form, is a fascinating compound with numerous implications in both medicinal chemistry and research. Here are some key points to consider:

  • Structure and Function: This compound features a unique combination of a chlorobenzene ring and an ethylamino group, which contributes to its interesting pharmacological properties.
  • Potential Applications: Due to its structural characteristics, it has piqued the interest of researchers in areas such as:
    • Neuroscience, where it may act on neuroreceptors.
    • Pharmaceutical development for psychostimulants.
  • Research Interest: Studies have suggested that compounds with similar structures may play roles in treatments for various disorders, including:
    • Anxiety and depression.
    • ADHD.
  • Legal Status: It is essential for researchers and students to be aware of the compound's legal status in various countries, as it falls into a category of substances that could be regulated due to their potential for misuse.
  • Caution Required: When handling or studying compounds like 1-(4-chlorophenyl)-2-(ethylamino)propan-1-one, strict safety protocols should be followed. Chemists must prioritize safety, including:
    • Using personal protective equipment (PPE).
    • Working in well-ventilated areas or fume hoods.

In summary, 1-(4-chlorophenyl)-2-(ethylamino)propan-1-one is a compound of significant interest within the fields of chemistry and medicine. Its unique structure opens doors to potential therapeutic applications, while also necessitating responsible handling and comprehension of its implications.

Synonyms
4-Chloroethcathinone
4-CEC
FWH-494
E5C1642KA2
SKF-70948
4'-Chloro-2-(ethylamino)propiophenone
14919-85-8
1-(4-Chloro-phenyl)-2-ethylamino-propan-1-one
UNII-E5C1642KA2
1-(4-Chlorophenyl)-2-(ethylamino)-1-propanone-d5
CHLOROETHCATHINONE
RefChem:1070538
1-(4-chlorophenyl)-2-(ethylamino)propan-1-one
SCHEMBL30473035
DTXSID80274909
DTXCID801782534
PAA91985
PD044623
NS00018078
N-ethyl-2-amino-1-(4-chlorophenyl)propan-1-one
Q27895634