Skip to main content

4-Chloroamphetamine

ADVERTISEMENT
Identification
Molecular formula
C10H14ClN
CAS number
5580-33-2
IUPAC name
1-(4-chlorophenyl)-2-methyl-propan-2-amine
State
State

At room temperature, 4-Chloroamphetamine exists as a crystalline solid. It is stable under ordinary conditions of use and storage.

Melting point (Celsius)
144.00
Melting point (Kelvin)
417.15
Boiling point (Celsius)
217.00
Boiling point (Kelvin)
490.15
General information
Molecular weight
169.68g/mol
Molar mass
169.6540g/mol
Density
1.0390g/cm3
Appearence

4-Chloroamphetamine typically appears as a white to off-white crystalline powder. It can also be found in the form of crystals or granules, and its color might vary slightly depending on purity and preparation method.

Comment on solubility

Solubility of 1-(4-chlorophenyl)-2-methyl-propan-2-amine

The solubility of 1-(4-chlorophenyl)-2-methyl-propan-2-amine, also known as a substituted amphetamine derivative, is influenced by several factors including its molecular structure and the polarity of the solvent used.

Key Factors Influencing Solubility:

  • Molecular Structure: The presence of the 4-chlorophenyl group contributes to hydrophobic characteristics, whereas the amine group can interact favorably with polar solvents.
  • Polarity: The compound exhibits both hydrophobic and hydrophilic properties, which can lead to variable solubility in different solvents.
  • Temperature: Increased temperature generally enhances solubility, allowing for greater dissolution of the compound in solvents.

In general, this compound is likely to have limited solubility in water but may be more soluble in organic solvents such as methanol or ethanol. As a result, to achieve optimal dissolution, it is important to choose a solvent that aligns with the compound's unique structural characteristics. Remember, "like dissolves like," so matching polarities is essential in predicting solubility.

In laboratory settings, researchers often assess solubility through empirical testing, allowing for a deeper understanding of a compound's behavior in various environments.

Interesting facts

Interesting Facts about 1-(4-chlorophenyl)-2-methyl-propan-2-amine

1-(4-chlorophenyl)-2-methyl-propan-2-amine, commonly referred to as an important compound in medicinal chemistry, showcases unique properties and potential applications. Here are some intriguing aspects of this compound:

  • Pharmacological Interest: This compound is often explored for its potential as a psychoactive substance, particularly due to its structural similarity to certain neurotransmitters. It's a subject of study in contexts related to mental health treatments.
  • Chlorophenyl Group: The presence of the 4-chlorophenyl substituent is noteworthy. This group can significantly influence the biological activity and pharmacokinetics of the compound, making it a focal point for researchers.
  • Understanding Structure-Activity Relationships: Researchers utilize this compound to better understand how structural modifications impact activity. This aids in the design of more effective pharmaceuticals with fewer side effects.
  • Historical Context: Compounds like this were originally synthesized during the search for major antidepressants and stimulants, contributing to the foundation of understanding mood disorders.
  • Environmental Implications: As with many amines, the environmental stability and degradation mechanisms of this compound are important areas of study, particularly in terms of its potential impact on ecosystems.

In summary, 1-(4-chlorophenyl)-2-methyl-propan-2-amine is more than just a series of atoms; it represents the intersection of chemistry and biology with ongoing research efforts aimed at unlocking its full potential. As one researcher aptly put it, "Understanding the detailed mechanisms of such compounds can illuminate pathways to novel therapeutic options."

Synonyms
CHLORPHENTERMINE
Clorfentermina
Desopimon
461-78-9
Teramine
Effox
1-(4-chlorophenyl)-2-methylpropan-2-amine
Chlorophentermine
Lucofen SA
Clorfentermina [INN-Spanish]
Chlorphenterminum [INN-Latin]
Chlorphenteramine
Chlorphenterminum
Chlorphentermine [INN:BAN]
1-(p-Chlorophenyl)-2-methyl-2-aminopropane
HSDB 3303
alpha,alpha-Dimethyl-p-chlorophenethylamine
p-Chloro-alpha,alpha-dimethylphenethylamine
4-Chloro-alpha,alpha-dimethylphenethylamine
2-(4-CHLORO-PHENYL)-1,1-DIMETHYL-ETHYLAMINE
EINECS 207-314-9
4-Chloro-alpha,alpha-dimethylbenzeneethanamine
UNII-NHW07912O7
BRN 1099928
Benzeneethanamine, 4-chloro-alpha,alpha-dimethyl-
Lucofen (Salt/Mix)
beta-(p-Chlorophenyl)-alpha,alpha-dimethylethylamine
1-(p-Chlorophenyl)-2-methyl-2-propylamine
NHW07912O7
CHLORPHENTERMINE [MI]
CHLORPHENTERMINE [INN]
CHLORPHENTERMINE [HSDB]
CHEBI:3646
DTXSID0022806
CHLORPHENTERMINE [WHO-DD]
Phenethylamine, p-chloro-alpha,alpha-dimethyl-
p-Chloro-.alpha.,.alpha.-dimethylphenethylamine
a,a-Dimethyl-p-chlorophenethylamine
4-12-00-02823 (Beilstein Handbook Reference)
4-Chloro-a,a-dimethylphenethylamine
Phenethylamine, p-chloro-.alpha.,.alpha.-dimethyl-
Benzeneethanamine, 4-chloro-.alpha.,.alpha.-dimethyl-
4-Chloro-a,a-dimethylbenzeneethanamine
DEA No. 1645
1-(4-chlorophenyl)-2-methyl-propan-2-amine
4-Chloro-.alpha.,.alpha.-dimethylphenethylamine
4-Chloro-.alpha.,.alpha.-dimethylbenzeneethanamine
Clorfentermina (INN-Spanish)
Chlorphenterminum (INN-Latin)
.beta.-(p-Chlorophenyl)-.alpha.,.alpha.-dimethylethylamine
BENZENEETHANAMINE, 4-CHLORO-.ALPHA.,.ALPHA.-DIMETHYL
NCGC00160422-01
1,1-dimethyl-2-(4-chlorophenyl)ethylamine
ChemDiv2_002573
Oprea1_632031
SCHEMBL160516
DTXCID202806
CHEMBL1201269
SCHEMBL11577478
BDBM85704
HMS1376E21
NSC_10007
STK664067
AKOS005535680
AB02276
DB01556
CAS_461-78-9
DB-013307
EU-0053624
NS00031586
1-(4-Chlorophenyl)-2-methyl-2-propanamine #
C07559
Q5103230
BENZENEETHANAMINE, 4-CHLORO-ALPHA,ALPHA-DIMETHYL
207-314-9