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4-chlorophenylthiouracil

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Identification
Molecular formula
C10H7ClN2O2S
CAS number
1823-16-3
IUPAC name
1-(4-chlorophenyl)-2-sulfanyl-pyrimidine-4,6-dione
State
State

At room temperature, 4-chlorophenylthiouracil is typically found in a solid state. It is stable under normal conditions, making it suitable for various laboratory and industrial applications.

Melting point (Celsius)
219.00
Melting point (Kelvin)
492.15
Boiling point (Celsius)
420.00
Boiling point (Kelvin)
693.15
General information
Molecular weight
242.68g/mol
Molar mass
242.6750g/mol
Density
1.5610g/cm3
Appearence

4-Chlorophenylthiouracil appears as a white crystalline powder. It is often noted for its distinct structure, having a pyrimidine dione core with a 4-chlorophenyl and a thiol group attached, contributing to its unique properties and chemical reactivity.

Comment on solubility

Solubility of 1-(4-chlorophenyl)-2-sulfanyl-pyrimidine-4,6-dione

The solubility of 1-(4-chlorophenyl)-2-sulfanyl-pyrimidine-4,6-dione can be an intriguing aspect of its chemical behavior. Understanding the solubility of a compound is essential in predicting its applications, reactivity, and performance in various conditions. Here are some key points concerning its solubility:

  • Polarity: The presence of the chlorophenyl group and the sulfanyl functional group suggests that this compound may exhibit moderate polarity, which can influence its solubility in various solvents.
  • Solvent Compatibility: Typically, compounds with similar polarities tend to be soluble in one another. Therefore, 1-(4-chlorophenyl)-2-sulfanyl-pyrimidine-4,6-dione may be soluble in:
    • Polar solvents (e.g., dimethyl sulfoxide, DMSO)
    • Some organic solvents (e.g., ethanol, methanol)
  • Temperature Influence: Like many organic compounds, its solubility may increase with temperature. Thus, heating the solvent could enhance solubility.
  • pH Considerations: The solubility can also be affected by the pH of the solution, particularly due to the functional groups present that may ionize under different pH conditions.

In summary, the solubility of 1-(4-chlorophenyl)-2-sulfanyl-pyrimidine-4,6-dione revolves around multiple factors, including the chemical structure, polarity, and external conditions like solvent choice and temperature. As with many compounds, practical experimentation is crucial to determine the precise solubility characteristics.

Interesting facts

Exploring 1-(4-chlorophenyl)-2-sulfanyl-pyrimidine-4,6-dione

1-(4-chlorophenyl)-2-sulfanyl-pyrimidine-4,6-dione is a compound that garners interest within the fields of medicinal chemistry and synthetic organic chemistry. Its unique structure exhibits several fascinating attributes:

  • Pharmacological Potential: This compound has been studied for its potential as a pharmaceutical agent, particularly in the realm of anticancer research. The pyrimidine ring is known for its role in various biological activities, making this compound a candidate for drug development.
  • Diversity of Applications: Beyond medicinal uses, compounds similar to this one are often explored for their utility in agrochemicals and as intermediates in organic synthesis.
  • Structural Features: The presence of the –Cl group (chlorophenyl) and the –SH group (sulfanyl) contributes to its reactivity and interaction with biological targets, which can be crucial for its function.

In the world of chemistry, the integration of various functional groups and the exploration of structure-activity relationships are vital. As a researcher delving into this compound, one might ask:

“What modifications can enhance its efficacy or reduce side effects?”

Researching 1-(4-chlorophenyl)-2-sulfanyl-pyrimidine-4,6-dione encourages scientists to innovate and think outside the box, exploring the depths of organic synthesis and drug design.