Clorotepine | Solubility of Things

Identification

Molecular formula

C₂₅H₂₇ClNO₂

CAS number

17086-61-2

IUPAC name

1-(4-chlorophenyl)-3-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-prop-2-en-1-one

State

It exists as a solid at room temperature.

Melting point (Celsius)

186.00

Melting point (Kelvin)

459.15

Boiling point (Celsius)

481.20

Boiling point (Kelvin)

754.35

General information

Molecular weight

425.95g/mol

Molar mass

425.9510g/mol

Density

1.1043g/cm³

Appearence

The compound typically appears as a yellow crystalline powder.

Comment on solubility

Solubility of 1-(4-chlorophenyl)-3-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-prop-2-en-1-one

The solubility of the compound 1-(4-chlorophenyl)-3-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-prop-2-en-1-one is influenced by several factors due to its complex molecular structure. This compound can be classified as a member of organic compounds that typically show varied solubility characteristics. Here are some key points to consider:

Polarity: The presence of both polar and non-polar functional groups within the molecule affects its overall polarity, impacting its solubility.
Solvent Interaction: Generally, this compound would be more soluble in organic solvents such as dichloromethane or ethanol rather than in water due to its hydrophobic phenyl groups.
Temperature: Increasing temperature can enhance solubility, aligning with the principle that solubility of solids in liquids often increases with temperature.
pH Effects: The presence of basic amine groups in the structure might lead to changes in solubility with varying pH levels, potentially increasing solubility in acidic solutions.

In conclusion, while detailed empirical solubility data may be scarce, it's evident that the structural features of 1-(4-chlorophenyl)-3-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-prop-2-en-1-one contribute to a nuanced solubility profile that would require careful evaluation in practical applications.

Interesting facts

Interesting Facts about 1-(4-chlorophenyl)-3-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-prop-2-en-1-one

This compound is a fascinating member of the class of compounds known as chalcones, which are recognized for their remarkable structural and biological properties. Here’s what makes this compound particularly intriguing:

Pharmaceutical Potential: Chalcones have been extensively studied for their diverse pharmacological activities, including anti-inflammatory, antioxidant, and anti-cancer properties. This specific compound's unique side chains could enhance its bioactivity.
Structural Diversity: The presence of various functional groups, such as the diethylamino and chlorophenyl moieties, provides the compound with unique electronic properties. This diversity allows scientists to explore and manipulate its chemical behavior in innovative ways.
Synthesis: The synthesis of chalcones typically involves the Claisen-Schmidt condensation, where aromatic aldehydes react with ketones in the presence of a base. The formation of such compounds can yield interesting variants with tailored biological activity.
Biological Importance: Research indicates that compounds like this one may serve as lead compounds in drug design, particularly targeting specific types of cancer cells. Their ability to inhibit cell proliferation makes them a subject of ongoing research.
Chemical Reactions: Due to its enone structure, this compound can undergo Michael additions, providing opportunities for further derivatization, which is essential in designing new pharmaceutical agents.

In conclusion, 1-(4-chlorophenyl)-3-[4-[2-(diethylamino)ethoxy]phenyl]-2-phenyl-prop-2-en-1-one stands at the intersection of organic chemistry and medicinal chemistry, showcasing the potential applications of chalcones in drug development. The exploration of such compounds not only expands our knowledge of organic synthesis but also holds promise for addressing various health challenges.