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Carbamazepine

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Identification
Molecular formula
C15H12ClNO2
CAS number
298-46-4
IUPAC name
1-(4-chlorophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione
State
State

Carbamazepine is typically a solid at room temperature, typically appearing in a crystalline powder form.

Melting point (Celsius)
190.50
Melting point (Kelvin)
463.70
Boiling point (Celsius)
402.60
Boiling point (Kelvin)
675.80
General information
Molecular weight
236.27g/mol
Molar mass
236.2720g/mol
Density
1.4980g/cm3
Appearence

Carbamazepine is a white to off-white crystalline powder, practically insoluble in water, and sparingly soluble in alcohol and acetone. It may appear as a solid at room temperature, often in a powder or crystalline form.

Comment on solubility

Solubility of 1-(4-chlorophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione

The solubility of 1-(4-chlorophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione is an intriguing aspect worth exploring. Given its complex structure, one can anticipate the following solubility characteristics:

  • Polarity: The presence of both the 4-chlorophenyl group and the dione functional groups suggests that the compound may tend to exhibit a moderate level of polarity.
  • Solvent Compatibility: It is likely to be more soluble in polar solvents such as methanol or ethanol compared to non-polar solvents like hexane due to interactions with the solvent molecules.
  • Hydrogen Bonding: The ability to form hydrogen bonds with solvent molecules could enhance its solubility in certain aqueous environments, especially in the presence of polar protic solvents.

In summary, while precise solubility data may vary based on experimental conditions, this compound's solubility profile is influenced by its molecular structure and the nature of the solvent. As a rule of thumb, "like dissolves like," so understanding the interaction between this compound and various solvents can aid in predicting its behavior in different environments.

Interesting facts

Interesting Facts about 1-(4-chlorophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione

1-(4-chlorophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione is a fascinating compound with intriguing structural features and potential applications in medicinal chemistry. Here are some noteworthy facts:

  • Structure and Class: This compound belongs to a class of bicyclic compounds characterized by a nitrogen atom in the ring structure, which contributes to its unique chemical properties.
  • Potential Pharmacological Activities: Compounds like this one may exhibit diverse biological activities, making them subjects of interest in drug discovery and development.
  • Chlorination Effect: The presence of a chlorophenyl group can enhance the lipophilicity of the compound, possibly improving its ability to cross biological membranes.
  • Interdisciplinary Appeal: Its complex structure makes it an excellent candidate for research across various disciplines, including organic synthesis, medicinal chemistry, and pharmacology.

Researchers often highlight how compounds with bicyclic structures can provide unique mechanisms of action. As noted by some pharmaceutical chemists, “The intricate design of such molecules can lead to surprising biological activities.”
In conclusion, 1-(4-chlorophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione serves as a pertinent example of the innovation found in synthetic chemistry. Its distinctive features and potential applications underscore the importance of continued research in this exciting field.

Synonyms
Ciproximida
1-(4-chlorophenyl)-3-azabicyclo[3.1.0]hexane-2,4-dione
SCHEMBL121879
CHEMBL2104097
DTXSID70864595
YYGANUVABKDFDW-UHFFFAOYSA-N
NS00010486
D02654
1-(4-chlorophenyl)-3-azabicyclo[3.1.0]hexane-2,4-quinone