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Clorazepate

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Identification
Molecular formula
C21H23ClNO3
CAS number
23887-31-2
IUPAC name
1-(4-chlorophenyl)-3-phenyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one
State
State

At room temperature, clorazepate is a solid. It is stable under normal temperatures and pressures.

Melting point (Celsius)
139.50
Melting point (Kelvin)
412.65
Boiling point (Celsius)
425.00
Boiling point (Kelvin)
698.15
General information
Molecular weight
388.91g/mol
Molar mass
388.9090g/mol
Density
1.2210g/cm3
Appearence

Clorazepate typically appears as a white to light yellow crystalline powder. It is usually odorless and is often supplied in tablet form for pharmaceutical use.

Comment on solubility

Solubility of 1-(4-chlorophenyl)-3-phenyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one

The solubility of 1-(4-chlorophenyl)-3-phenyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one can be influenced by several factors including its molecular structure, temperature, and the solvent used. Here are some considerations regarding its solubility:

  • Polar vs Nonpolar Solvents: This compound features both polar (due to the -O- ether group) and nonpolar regions (due to the phenyl and chlorophenyl groups). Therefore, it may find better solubility in a mixture of polar and nonpolar solvents.
  • Temperature Effects: Like many organic compounds, its solubility is likely to increase with temperature. This behavior could encourage dissolution in hot solvents, making it useful in various applications.
  • Hydrogen Bonding: Its structure suggests potential hydrogen bonding interactions due to the pyrrolidine unit, which may facilitate its solubility in some polar solvents.
  • Crystallization: The compound’s tendency to crystallize may also affect its solubility; if it forms stable crystals, this could lead to lower solubility in certain solvents.

In conclusion, the solubility of this complex compound is multi-faceted and can be adapted based on the solvent system and external conditions. Understanding these interactions is crucial for practical applications in pharmacology and material science.

Interesting facts

Interesting Facts about 1-(4-Chlorophenyl)-3-phenyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one

This compound, a member of the chalcone family, possesses unique structural and chemical characteristics that make it a fascinating subject of study in organic chemistry.

Key Highlights:

  • Chalcone Structure: Chalcones are known for their ability to undergo various chemical reactions, such as isomerization and polymerization, making them versatile intermediates in organic synthesis.
  • Biological Activity: Certain derivatives of chalcones have been reported to exhibit significant biological properties, including anti-inflammatory, antioxidant, and anticancer activities. This compound likely follows suit, potentially offering insights into new therapeutic avenues.
  • Pharmacological Relevance: The incorporation of a pyrrolidine moiety can enhance the biological activity and interaction profile of pharmaceutical compounds, potentially increasing efficacy in targeted therapies.

As a chemistry student or researcher, one might be particularly interested in exploring:

  1. Synthesis Methods: Investigating various synthetic routes to design chalcone derivatives can lead to the development of new compounds with enhanced properties.
  2. Mechanistic Studies: Understanding the reaction mechanisms involved in their formation and transformations can shed light on fundamental organic reactions.
  3. Application in Materials Science: Chalcones have also been explored for their potential use in materials, particularly in the development of organic electronics and photonic devices.

In summary, 1-(4-chlorophenyl)-3-phenyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]prop-2-en-1-one not only exemplifies the diversity of chalcone compounds but also stands at the intersection of synthetic organic chemistry and medicinal applications. Its study could pave the way for advances in both fields!