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Chlorphenesin carbamate

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Identification
Molecular formula
C11H15ClNO2
CAS number
104-29-0
IUPAC name
1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethyl-butan-2-ol
State
State

At room temperature, chlorphenesin carbamate is a solid compound.

Melting point (Celsius)
90.00
Melting point (Kelvin)
363.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
255.74g/mol
Molar mass
255.7740g/mol
Density
1.2170g/cm3
Appearence

Chlorphenesin carbamate appears as a white to off-white crystalline powder. It is generally odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethyl-butan-2-ol

The solubility of 1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethyl-butan-2-ol, a complex organic compound, can vary significantly based on several factors. Here are some important points to consider:

  • Solvent Dependency: This compound may exhibit different solubility profiles in various solvents, such as water, ethanol, or DMSO. For polar solvents like water, solubility could be limited due to the presence of hydrophobic groups.
  • Temperature Impact: Temperature plays a crucial role in solubility; generally, increasing temperature enhances solubility for many organic compounds.
  • pH Sensitivity: The acidity or basicity of the solvent can influence solubility, particularly for compounds containing amine groups, rendering it more soluble in acidic conditions.
  • Structural Features: The presence of a chlorophenyl group and a dimethylamino group may introduce steric hindrance and affect intermolecular interactions, which can further complicate solubility characteristics.

In summary, the solubility of this compound is a nuanced property shaped by its molecular structure and the surrounding chemical environment. Careful experimentation is often required to assess solubility and optimize conditions for desired applications.

Interesting facts

Interesting Facts about 1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethyl-butan-2-ol

1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethyl-butan-2-ol is a fascinating compound that has drawn attention in various fields such as organic chemistry and medicinal applications. Here are some intriguing points regarding this compound:

  • Pharmacological Interest: This compound, known for its unique structure, has potential pharmacological activities, particularly as an intermediate in the synthesis of various pharmaceuticals. Its functional groups make it a versatile building block in drug discovery.
  • Chirality: The compound possesses chirality due to the presence of a stereocenter. This characteristic is vital, as it can lead to differences in biological activity between its enantiomers, making it an excellent candidate for chiral synthesis studies.
  • Role in Organic Synthesis: The presence of the dimethylamino group enhances nucleophilicity, making this compound a useful reagent in various organic transformations, such as alkylation and acylation reactions.
  • Potential Applications: Targeted research is being conducted to explore the applicability of this compound in synthesizing compounds with altered pharmacokinetics and pharmacodynamics, which can lead to new therapeutic agents.
  • Electrophilic Substitution: The chlorophenyl moiety in the compound can serve as a site for electrophilic substitution reactions, paving the way for further functionalization and diversification of the compound's structure.

This compound exemplifies the complexity and potential of organic chemicals in modern chemistry. Its varied applications and fascinating structural attributes make it a subject of ongoing research and interest in the scientific community.

Synonyms
Clobutinol
14860-49-2
Clobutinolum
Iversal
1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethylbutan-2-ol
1NY2IX043A
R05DB03
KAT 256 FREE BASE
KAT-256 FREE BASE
DTXSID2022838
4-Chloro-alpha(2-(dimethylamino)-1-methylethyl)alpha-methylbenzeneethanol
Benzeneethanol, 4-chloro-alpha-(2-(dimethylamino)-1-methylethyl)-alpha-methyl-
chlorodimenol
clobutinolo
DTXCID902838
238-926-4
Clobutinol [INN]
Clobutinol (INN)
Iversal (TN)
1-(4-Chlorophenyl)-2,3-dimethyl-4-dimethylamino-2-butanol
C14H22ClNO
KAT 256 [AS HYDROCHLORIDE]
Clobutinolum [INN-Latin]
Benzeneethanol, 4-chloro-.alpha.-[2-(dimethylamino)-1-methylethyl]-.alpha.-methyl-
NCGC00159437-02
EINECS 238-926-4
BRN 2843490
UNII-1NY2IX043A
BENZENEETHANOL, 4-CHLORO-.ALPHA.-(2-(DIMETHYLAMINO)-1-METHYLETHYL)-.ALPHA.-METHYL-
CLOBUTINOL [MI]
Benzeneethanol, 4-chloro-alpha-(2-(dimethylamino)-1-methyl)-alpha-methyl-
p-Chloro-alpha-(2-(dimethylamino)-1-methylethyl)-alpha-methyl-phenethyl alcohol
CLOBUTINOL [WHO-DD]
p-Cloro-alpha-(2-(dimetilamino)-1-metiletil)-alpha-metil fenetil alcool [Italian]
SCHEMBL148543
orb1689627
CHEMBL1474889
CHEBI:94381
EX-A12354
p-Chloro-alpha-(2-(dimethylamino)-1-methylethyl)-alpha-methylphenethyl alcohol
p-Cloro-alpha-(2-(dimetilamino)-1-metiletil)-alpha-metil fenetil alcool
DB09004
Phenethyl alcohol, p-chloro-.alpha.-[2-(dimethylamino)-1-methylethyl]-.alpha.-methyl-
Phenethyl alcohol, p-chloro-alpha-(2-(dimethylamino)-1-methylethyl)-alpha-methyl-
DA-72275
HY-148144
CS-0613654
NS00002717
D07716
Diethylenetriamine crosslinked with epichlorohydrin
Q415654
BRD-A43809092-003-01-3
BRD-A43809092-003-02-1
1-(4-chlorophenyl)-4-(dimethylamino)-2,3-dimethyl-2-butanol
Benzeneethanol, 4-chloro-.alpha.-(2-(dimethylamino)-1-methyl)-.alpha.-methyl-
p-Chloro-.alpha.-(2-(dimethylamino)-1-methylethyl)-.alpha.-methyl-phenethyl alcohol
P-CHLORO-.ALPHA.-(2-(DIMETHYLAMINO)-1-METHYLETHYL)-.ALPHA.-METHYLPHENETHYL ALCOHOL
p-Chloro-.alpha.-[2-(dimethylamino)-1-methylethyl]-.alpha.-methylphenyl alcohol
p-Cloro-.alpha.-(2-(dimetilamino)-1-metiletil)-.alpha.-metil fenetil alcool