Skip to main content

4-Chloromethamphetamine

ADVERTISEMENT
Identification
Molecular formula
C13H18ClN
CAS number
32944-08-2
IUPAC name
1-(4-chlorophenyl)-N-(cyclopropylmethyl)propan-2-amine
State
State

At room temperature, 4-Chloromethamphetamine is typically found in a solid state.

Melting point (Celsius)
95.00
Melting point (Kelvin)
368.15
Boiling point (Celsius)
185.00
Boiling point (Kelvin)
458.15
General information
Molecular weight
211.75g/mol
Molar mass
211.7240g/mol
Density
1.0234g/cm3
Appearence

4-Chloromethamphetamine typically appears as a crystalline solid substance, often colorless or white in appearance. It may also form in fine powder or crystalline shards.

Comment on solubility

Solubility of 1-(4-chlorophenyl)-N-(cyclopropylmethyl)propan-2-amine

The solubility of 1-(4-chlorophenyl)-N-(cyclopropylmethyl)propan-2-amine can be influenced by various factors, including temperature, solvent type, and chemical structure. This compound, with a complex aromatic and aliphatic configuration, may exhibit distinctive solubility characteristics. Here are key points to consider:

  • Polarity: The presence of a chlorophenyl group increases the molecular polarity, potentially enhancing solubility in polar solvents like water to some extent.
  • Functional Groups: The amine group can engage in hydrogen bonding, making the compound more soluble in solvents that can accept hydrogen bonds.
  • Hydrophobic Regions: The cyclopropylmethyl moiety introduces hydrophobic characteristics, which could reduce solubility in purely polar solvents.
  • General Trends: Typically, compounds with more complex structures or higher molecular weights tend to have lower solubility in water.

In conclusion, while 1-(4-chlorophenyl)-N-(cyclopropylmethyl)propan-2-amine is likely to display some degree of solubility due to its polar functional groups, the balance between its polar and non-polar characteristics may result in limited solubility in aqueous environments. Thus, empirical testing in various solvents would be essential to determine its precise solubility behavior.

Interesting facts

1-(4-chlorophenyl)-N-(cyclopropylmethyl)propan-2-amine - An Intriguing Chemical Compound

This unique compound belongs to a class of chemicals known as amines, which are characterized by the presence of nitrogen atoms. Amine compounds are essential in various biological processes and are fundamental building blocks in organic chemistry. Here are some compelling facts about 1-(4-chlorophenyl)-N-(cyclopropylmethyl)propan-2-amine:

  • Substituted Phenyl Group: The presence of a 4-chlorophenyl group introduces intriguing electronic properties that can significantly affect the compound's reactivity and biological activity. The chlorine atom is an electron-withdrawing group, potentially influencing the compound's interaction with biological targets.
  • Cyclopropylmethyl Feature: The cyclopropylmethyl moiety is of particular interest due to its unique three-membered ring structure, which is known for introducing strain. Such structural features can lead to interesting conformational behaviors in chemical reactions.
  • Psychoactive Properties: Compounds similar to 1-(4-chlorophenyl)-N-(cyclopropylmethyl)propan-2-amine are often investigated for their potential psychoactive effects. The study of amines in pharmacology has led to the development of various therapeutic agents, making this compound a subject of research in medicinal chemistry.
  • Research Applications: This compound is significant in the realm of research, particularly in synthesizing new drugs or understanding the mechanisms behind certain neurological conditions. Its ability to interact with neurotransmitter systems could hold the key to potential treatments.
  • Structural Diversity: The structural variations within amine compounds, like the one discussed, make them fascinating subjects for synthetic organic chemistry. Altering the phenyl or cyclopropyl groups can lead to entirely different properties, emphasizing the importance of structure-activity relationships (SAR) in drug design.

In summary, 1-(4-chlorophenyl)-N-(cyclopropylmethyl)propan-2-amine serves as a reminder of the rich diversity and complexity within chemical compounds. Its unique structure not only sparks curiosity in the academic community but also drives significant research efforts aimed at exploring its potential applications in medicine and beyond.

Synonyms
WAM4HF7BU4
N-(CYCLOPROPYLMETHYL)-4-CHLORO-ALPHA-METHYLPHENETHYLAMINE
22702-10-9
(1-(4-Chlorophenyl)propan-2-yl)(cyclopropylmethyl)amine
4-Chloro-N-(cyclopropylmethyl)-alpha-methylbenzeneethanamine
Phenethylamine, p-chloro-N-(cyclopropylmethyl)-alpha-methyl-
Benzeneethanamine, 4-chloro-N-(cyclopropylmethyl)-alpha-methyl-
Phenethylamine, p-chloro-N-(cyclopropylmethyl)-.alpha.-methyl-
Benzeneethanamine, 4-chloro-N-(cyclopropylmethyl)-.alpha.-methyl-
4-CHLORO-N-(CYCLOPROPYLMETHYL)-.ALPHA.-METHYLBENZENEETHANAMINE
N-(CYCLOPROPYLMETHYL)-4-CHLORO-.ALPHA.-METHYLPHENETHYLAMINE
[1-(4-chlorophenyl)propan-2-yl](cyclopropylmethyl)amine
RefChem:202036
666-644-5
UNII-WAM4HF7BU4
AKOS009876802