Interesting facts
Interesting Facts about 1-[(4-chlorophenyl)-phenyl-methyl]piperazine
1-[(4-chlorophenyl)-phenyl-methyl]piperazine, often abbreviated to its more complex name, is a fascinating compound with a variety of implications in the fields of medicinal chemistry and pharmacology. As a derivative of piperazine, it boasts a unique structure that allows for intriguing interactions with biological systems.
Chemical Characteristics and Applications
- Antidepressant Potential: The compound has been studied for its possible antidepressant effects, making it a subject of interest in the development of new mental health therapies.
- Neurotransmitter Interactions: Its structural configuration suggests that it may interact with neurotransmitter systems in the brain, particularly the serotonin and dopamine receptors.
- Structure-Activity Relationships: The presence of the 4-chlorophenyl group is significant, as chlorination can enhance the compound's potency and selectivity for specific receptors.
- Research Tool: Researchers often utilize such compounds to better understand the mechanisms of action for various psychiatric medications and to explore new avenues for treatment.
Safety and Regulatory Aspects
Like many compounds investigated for their pharmacological properties, 1-[(4-chlorophenyl)-phenyl-methyl]piperazine also calls for rigorous safety assessments. Regulatory bodies require:
- Thorough testing for toxicity.
- Evaluation of long-term effects on health.
- Compliance with medical standards before it can be classified for human use.
As a compound from the piperazine family, it highlights the intricate relationship between chemistry and biological outcomes. Its study and potential applications pave the way for future breakthroughs in treating mental health disorders, making it a captivating subject for both chemists and healthcare professionals.
Synonyms
1-(4-Chlorobenzhydryl)piperazine
303-26-4
Norchlorcyclizine
1-((4-chlorophenyl)(phenyl)methyl)piperazine
130018-88-1
1-[(4-Chlorophenyl)phenylmethyl]piperazine
N-(p-Chlorobenzhydryl)piperazine
4-(4-Chlorobenzhydryl)piperazine
1-[(4-Chlorophenyl)(phenyl)methyl]piperazine
N-(4-Chlorobenzhydryl)piperazine
Piperazine, 1-[(4-chlorophenyl)phenylmethyl]-
NSC 86164
(-)-1-[(4-chlorophenyl) phenylmethyl] piperazine
1-[(4-chlorophenyl)-phenylmethyl]piperazine
Cetirizine Impurity A
(-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
EINECS 206-137-4
MFCD00005965
Piperazine, 1-((4-chlorophenyl)phenylmethyl)-
BRN 0243027
T875VN0D6E
1-(4-Chloro-alpha-phenylbenzyl)piperazine
1-(alpha-Phenyl-4-chlorobenzyl)piperazine
1-(.alpha.-Phenyl-4-chlorobenzyl)piperazine
1-(4-Chloro-.alpha.-phenylbenzyl)piperazine
NSC-86164
Piperazine, 1-(alpha-(4-chlorophenyl)benzyl)-
1-((4-chlorophenyl)phenylmethyl)piperazine
DTXSID00891490
4-23-00-00072 (Beilstein Handbook Reference)
PIPERAZINE, 1-(p-CHLORO-alpha-PHENYLBENZYL)-
NORCHLORCYCLIZINE, (+/-)-
N-(4-Chlorophenyl)phenylmethylpiperazine
(+/-)-1-(P-CHLOROBENZHYDRYL)PIPERAZINE
CPP_287.1310_14.5
Piperazine, 1-(p-chloro-.alpha.-phenylbenzyl)-
(RS)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
1-[(R)-(4-chlorophenyl)-phenyl-methyl]piperazine
CETIRIZINE DIHYDROCHLORIDE IMPURITY A [EP IMPURITY]
HYDROXYZINE HYDROCHLORIDE IMPURITY A [EP IMPURITY]
MECLOZINE DIHYDROCHLORIDE IMPURITY H [EP IMPURITY]
(S)-(+)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
1-[(4-chlorophenyl)phenylmethyl)piperazine
Piperazine, 1-(.alpha.-(4-chlorophenyl)benzyl)-
Piperazine, 1-[.alpha.-(4-chlorophenyl)benzyl]-
1-(4-Chlorodiphenylmethyl)piperazine
(R)-(-)-1-[(4-Chlorophenyl)phenylmethyl]piperazine
CETIRIZINE DIHYDROCHLORIDE IMPURITY A (EP IMPURITY)
HYDROXYZINE HYDROCHLORIDE IMPURITY A (EP IMPURITY)
MECLOZINE DIHYDROCHLORIDE IMPURITY H (EP IMPURITY)
UNII-T875VN0D6E
4-chlorobenzhydryl piperazine
4-CHLOROBENZHYDRYLPIPERAZINE
1-(4-Chlorobenzhydryl) piperazine
Meclozine impurity H
CBHP
(S)-Nor-CCZ
Levocetirizine Impurity 2
1-[(4-chlorophenyl)-phenyl-methyl]piperazine
Oprea1_771131
MLS000521343
CHEMBL81324
SCHEMBL467086
GTPL9162
98% +(contains <7%H2O)
DTXCID70220253
GLXC-04310
HMS1648P05
HMS2464F07
BCP08791
BCP34517
NSC86164
BBL010366
STK083473
AKOS000268792
AKOS016039386
AC-3019
CS-W001978
FC20350
GF-0133
HY-W001978
SB47944
NCGC00245963-01
compound C10 [PMID: 24297249]
SMR000131751
SY003580
DB-018556
C1611
EU-0099994
NS00000628
1-[(4-chlorophenyl)-phenylmethyl]-piperazine
EN300-18220
1-((4-Chlorophenyl)(phenyl)methyl)-piperazine
N-[(4-chlorophenyl)(phenyl)-methyl]piperazine
(-)-1-[(4chlorophenyl) phenylmethyl]piperazine
1-[(4-Chloro-phenyl)-phenyl-methyl]-piperazine
(-)-1-[(4-chloro phenyl)phenylmethyl]piperazine
SR-01000597190
SR-01000597190-1
(-)-1-[(4-Chloro-phenyl)-phenyl-methyl]-piperazine
Piperazine, 1-((4-chlorophenyl)phenylmethyl)-(9CI)
Q27076864
Z57388987
1-(4-Chlorobenzhydryl)piperazine, technical grade, 90%
CETIRIZINE HYDROCHLORIDE IMPURITY CBHP [USP IMPURITY]
Meclozine impurity H, European Pharmacopoeia (EP) Reference Standard
Cetirizine impurity A, European Pharmacopoeia (EP) Reference Standard
(R)-Cetirizine EP Impurity A;(R)-1-((4-Chlorophenyl)(phenyl)methyl)piperazine
206-137-4
Solubility of 1-[(4-chlorophenyl)-phenyl-methyl]piperazine
The solubility of 1-[(4-chlorophenyl)-phenyl-methyl]piperazine can vary significantly depending on the solvent used. This compound, being a piperazine derivative, exhibits certain characteristics that influence its solubility profile.
Factors Affecting Solubility:
In summary, the solubility of 1-[(4-chlorophenyl)-phenyl-methyl]piperazine is primarily influenced by its structure, where the balance between polar and non-polar characteristics dictates its behavior in various solvents. Empirical testing is crucial for accurate determination, allowing researchers to ascertain the best applications for this compound in practical scenarios.