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4-Chloroacetophenone

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Identification
Molecular formula
C8H7ClO
CAS number
532-27-4
IUPAC name
1-(4-chlorophenyl)ethanone
State
State

At room temperature, 4-Chloroacetophenone is typically a solid, taking the form of crystalline powder. It can emit fumes when exposed to heat or fire.

Melting point (Celsius)
88.00
Melting point (Kelvin)
361.15
Boiling point (Celsius)
244.00
Boiling point (Kelvin)
517.15
General information
Molecular weight
154.60g/mol
Molar mass
154.5750g/mol
Density
1.3190g/cm3
Appearence

4-Chloroacetophenone appears as white to off-white crystalline powder. It is a chemical compound characterized by its distinctive, pungent odor.

Comment on solubility

Solubility of 1-(4-chlorophenyl)ethanone

1-(4-chlorophenyl)ethanone, commonly known as 4-chloroacetophenone, exhibits interesting solubility characteristics that are relevant in various chemical processes.

Solubility Insights:

  • Solvent Dependence: This compound is relatively soluble in organic solvents such as ethanol, methanol, and acetone, while its solubility in water is quite limited.
  • Effect of Temperature: Typically, solubility increases with temperature in organic solvents, meaning that heating the solvent can enhance the dissolution of 1-(4-chlorophenyl)ethanone.
  • Polarity Consideration: Due to its aromatic ring and the presence of a carbonyl group, this compound exhibits polar characteristics, influencing its interaction with other substances.

In practice, this means that while 1-(4-chlorophenyl)ethanone may not easily dissolve in water, it finds good solubility in environments where organic solvents are present, making it useful in various scenarios. As a rule of thumb, always consider the solvent used when preparing solutions with this compound to ensure desired results.

Interesting facts

Interesting Facts about 1-(4-chlorophenyl)ethanone

1-(4-chlorophenyl)ethanone, commonly known as 4-Chloroacetophenone, is a fascinating compound that belongs to the family of ketones. It is widely recognized for its various applications in organic synthesis and industry. Here are some interesting facts about this compound:

  • Versatile Intermediate: This compound acts as a crucial intermediate in the synthesis of a variety of pharmaceutical and agrochemical products, making it invaluable in organic chemistry.
  • Role in Research: 4-Chloroacetophenone is often utilized in academic research for studies related to reaction mechanisms and synthetic methodologies.
  • Pungent Characteristics: Known for its strong odor, this compound has been used in self-defense sprays, such as pepper spray, where it serves as an irritant.
  • Chemical Behavior: The presence of the chloro group enhances the electrophilicity of the carbonyl carbon, allowing for various electrophilic reactions that are fundamental in synthetic organic chemistry.
  • Historical Context: Historically, 4-Chloroacetophenone has been of interest not only for its chemical properties but also for its role in the development of novel chemical processes during the evolution of modern chemistry.

This compound exemplifies the blend of practical applications and theoretical significance that characterizes much of organic chemistry. As a compound that bridges the gap between experimental research and real-world utility, 1-(4-chlorophenyl)ethanone remains an essential topic of study for chemists and students alike.

Synonyms
4'-Chloroacetophenone
99-91-2
1-(4-Chlorophenyl)ethanone
4-Chloroacetophenone
P-CHLOROACETOPHENONE
Ethanone, 1-(4-chlorophenyl)-
4-Acetylchlorobenzene
1-(4-Chlorophenyl)Ethan-1-One
Acetophenone, 4'-chloro-
p-Chloracetophenone
p-Acetylchlorobenzene
USAF DO-1
Methyl p-chlorophenyl ketone
p-Chlorophenyl methyl ketone
4-Chlorophenyl methyl ketone
Methyl 4-chlorophenyl ketone
1-(4-Chlorophenyl)-ethanone
4'-chloroacetophenone-d7
MFCD00000624
HSDB 2088
NSC 6115
EINECS 202-800-7
UNII-ZV4A71K303
BRN 0386014
1174565-85-5
AI3-01370
ZV4A71K303
NSC-6115
CHEMBL608419
DTXSID1052668
P-CHLOROACETOPHENONE [MI]
P-CHLOROACETOPHENONE [HSDB]
4-07-00-00639 (Beilstein Handbook Reference)
238399-91-2
pChloracetophenone
pChloroacetophenone
p-choroacetophenone
pAcetylchlorobenzene
4-chloracetophenone
4Acetylchlorobenzene
4'chloroacetophenone
p-chloro-acetophenone
4-chloro acetophenone
4-chloroace-tophenone
4`-Chloroacetophenone
4\'-Chloroacetophenone
Acetophenone, 4'chloro
acetophenone, p-chloro-
1(4Chlorophenyl)ethanone
Methyl pchlorophenyl ketone
pChlorophenyl methyl ketone
bmse000518
4Chlorophenyl methyl ketone
Methyl 4chlorophenyl ketone
WLN: GR DV1
Ethanone, 1(4chlorophenyl)
SCHEMBL75640
4'-Chloroacetophenone, 97%
1-(4-chloro-phenyl)-ethanone
ACETOPHENONE, 4-CHLORO-
DTXCID2031241
1-(4-chlorophenyl)ethane-1-one
NSC6115
CHEBI:230611
Acetophenone, 4'-chloro- (8CI)
BBL013140
BDBM50304447
STK400323
AKOS000118934
CS-W016264
FC05532
DA-56627
NS00040567
EN300-17998
4 inverted exclamation marka-Chloroacetophenone
C06647
N10056
Q27295903
Z57127462
F2147-0328