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4'-Chloropropiophenone

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Identification
Molecular formula
C9H9ClO
CAS number
6285-05-8
IUPAC name
1-(4-chlorophenyl)propan-1-one
State
State
At room temperature, the compound can exist as a liquid if pure or as a crystalline solid if impurities promote crystallization.
Melting point (Celsius)
11.00
Melting point (Kelvin)
284.15
Boiling point (Celsius)
252.00
Boiling point (Kelvin)
525.15
General information
Molecular weight
168.62g/mol
Molar mass
168.6190g/mol
Density
1.0840g/cm3
Appearence

4'-Chloropropiophenone is a colorless to light yellow liquid or sometimes crystalline solid. It has a characteristic odor and tends to form crystals upon standing depending on the storage conditions.

Comment on solubility

Solubility of 1-(4-chlorophenyl)propan-1-one

1-(4-chlorophenyl)propan-1-one, known for its intriguing chemical structure, exhibits specific solubility characteristics that are notable in various solvent systems. The solubility of this compound can be influenced by several factors, including:

  • Polarity of Solvent: This compound is relatively non-polar due to the presence of the chlorophenyl group. Therefore, it tends to be soluble in non-polar to moderately polar solvents such as hexane and ethyl acetate.
  • Temperature: As with many organic compounds, solubility can increase with temperature. Thus, heating the solvent may enhance the dissolution of 1-(4-chlorophenyl)propan-1-one.
  • Concentration: The extent of solubility will vary with concentration. In dilute solutions, the compound may exhibit different solubility behavior compared to concentrated solutions.

In general, 1-(4-chlorophenyl)propan-1-one is sparingly soluble in water, which can be attributed to its hydrophobic nature. It is essential to remember that the solubility of organic compounds like this one can dramatically change based on the factors mentioned above. Thus, for laboratory applications or syntheses, it is advisable to refer to specific solubility data when determining the best solvent to use.

Interesting facts

Interesting Facts about 1-(4-chlorophenyl)propan-1-one

1-(4-chlorophenyl)propan-1-one, often referred to as a significant ketone in organic chemistry, has various implications in both academia and industry. This compound is notable for its role as an intermediate in the synthesis of pharmaceuticals and agrochemicals.

Applications and Significance

  • Pharmaceutical Development: This compound serves as a precursor for many biologically active molecules, aiding in the discovery of new drugs.
  • Agrochemical Synthesis: Its derivatives are frequently used to develop herbicides and pesticides, showcasing its importance in agricultural science.
  • Research Applications: Researchers utilize 1-(4-chlorophenyl)propan-1-one in various studies to understand structure-activity relationships.

Chemical Properties

As a ketone, its functional group gives it characteristic reactivity that is often harnessed in organic transformations like nucleophilic additions.

Safety and Handling

Due to its reactive nature, safe handling is crucial. Always ensure proper protective gear and storage conditions.

Quote from a Researcher

"The versatility of 1-(4-chlorophenyl)propan-1-one in organic synthesis cannot be overstated. It frequently opens pathways to complex molecular architectures."

This compound exemplifies the intersection of chemistry and industry, where research and practical application meet to drive innovation.

Synonyms
4'-Chloropropiophenone
p-Chloropropiophenone
4-Chloropropiophenone
1-Propanone, 1-(4-chlorophenyl)-
PROPIOPHENONE, 4'-CHLORO-
Ethyl p-chlorophenyl ketone
Propiophenone, p-chloro-
USAF EK-5296
Ethyl 4-chlorophenyl ketone
1-(4-Chlorophenyl)-1-propanone
NSC 5600
26AY8WJA1E
DTXSID1048203
NSC-5600
EINECS 228-511-6
UNII-26AY8WJA1E
BRN 1100638
AI3-23870
DTXCID9028178
1-(4-chlorophenyl)propane-1-one
4-07-00-00683 (Beilstein Handbook Reference)
228-511-6
adcyrbxqajxjtd-uhfffaoysa-n
6285-05-8
1-(4-chlorophenyl)propan-1-one
MFCD00000626
NSC5600
4`-Chloropropiophenone
4\'-Chloropropiophenone
WLN: GR DV2
4-Chlorophenyl Ethyl Ketone
4'-CHLOROPROPIOPHENON
SCHEMBL196299
4'-Chloropropiophenone, 98%
CHEMBL2251218
1-(4-chloropenyl)propan-1-one
STR03376
1-(4-chloro-phenyl)-propan-1-one
Tox21_303381
STK397560
AKOS000120501
CS-W016035
FC37749
NCGC00257311-01
SY002144
CAS-6285-05-8
C1616
NS00015734
EN300-20251
4 inverted exclamation marka-Chloropropiophenone
S12307
4 inverted exclamation mark -Chloropropiophenone
Q27254084
F0001-1697
Z104477486