Interesting facts
Interesting Facts About 1-(4-Chlorophenyl)sulfonyl-3-propyl-urea
1-(4-Chlorophenyl)sulfonyl-3-propyl-urea is a fascinating compound that helps illustrate the diverse nature of ureas in medicinal chemistry. Here are some intriguing points about this compound:
- Pharmaceutical Relevance: This compound belongs to a class of urea derivatives that have been researched for their potential therapeutic effects, particularly in the realm of anti-inflammatory and analgesic medications.
- Chlorophenyl Influence: The presence of the 4-chlorophenyl group is significant as halogenated phenyl groups often enhance the biological activity of compounds and can improve their interaction with biological targets.
- Structure-Activity Relationship: The sulfonyl group plays a pivotal role in modulating the pharmacological properties of the compound, affecting factors such as solubility and reactivity, which are critical for drug design.
- Synthesis: The synthesis of this urea derivative often involves multi-step processes that can include the formation of sulfonamides and coupling reactions, showcasing the versatility of organic synthesis techniques.
- Impact on Agriculture: Beyond medicinal uses, derivatives similar to this compound have found applications in agricultural chemistry, serving as herbicides and pesticides due to their ability to inhibit certain biological pathways in plants.
In conclusion, 1-(4-Chlorophenyl)sulfonyl-3-propyl-urea exemplifies the complexity and utility of urea derivatives in modern chemistry. It serves as a reminder of the ongoing exploration in both medicinal and agricultural fields, where understanding the nuances of chemical structure can lead to significant advancements.
Synonyms
chlorpropamide
94-20-2
Chloropropamide
Diabinese
Chlorpropamid
Diabenese
Glucamide
Meldian
Chlorodiabina
Chloronase
Diabeneza
Diabetoral
Adiaben
Catanil
Diabaril
Dynalase
Insulase
Melitase
Diabechlor
Diabenal
Mellinese
Millinese
Asucrol
Glisema
Oradian
Diabet-Pages
Diamel Ex
Clorpropamida
Prodiaben
4-chloro-N-(propylcarbamoyl)benzenesulfonamide
1-(4-Chlorophenylsulfonyl)-3-propylurea
Chlorpropamidum
Clorpropamide
Diabexan
1-(p-Chlorobenzenesulfonyl)-3-propylurea
1-Propyl-3-(p-chlorobenzenesulfonyl)urea
N-(4-Chlorophenylsulfonyl)-N'-propylurea
N-(p-Chlorobenzenesulfonyl)-N'-propylurea
N-Propyl-N'-(p-chlorobenzenesulfonyl)urea
1-(4-chlorophenyl)sulfonyl-3-propylurea
1-(p-Chlorophenylsulfonyl)-3-propylurea
4-Chloro-N-((propylamino)carbonyl)benzenesulfonamide
1-p-Chlorophenyl-3-(propylsulfonyl)urea
NCI-C01752
n-Propyl-N'-p-chlorophenylsulfonylcarbamide
1-[(4-chlorobenzene)sulfonyl]-3-propylurea
4-chloro-N-[(propylamino)carbonyl]benzenesulfonamide
Benzenesulfonamide, 4-chloro-N-((propylamino)carbonyl)-
WTM2C3IL2X
N-Propyl-N'-p-chlorphenylsulfonylcarbamide
1-((p-Chlorophenyl)sulfonyl)-3-propylurea
4-Chloro-4-((propylamino)carbonyl)benzenesulfonamide
P 607
MFCD00079004
NSC 44634
NSC-44634
U-9818
NSC-626720
CHEBI:3650
1-(4-chlorobenzenesulfonyl)-3-propylurea
DTXSID9020322
Benzenesulfonamide, 4-chloro-N-[(propylamino)carbonyl]-
Clorpropamid
Urea, 1-((p-chlorophenyl)sulfonyl)-3-propyl-
CHEMBL498
DTXCID30322
MLS000028395
Bioglumin
Insogen
NSC44634
NSC626720
CAS-94-20-2
NCGC00015216-11
Chlorporpamide
SMR000058364
Clorpropamide [DCIT]
chlorpropamide, alpha-form
Clorpropamide [Italian]
Urea, 1-[(p-chlorophenyl)sulfonyl]-3-propyl-
chlorpropamide, epsilon-form
chlorpropamide, epsilon`-form
CHLORPROPAMIDE (MART.)
CHLORPROPAMIDE [MART.]
CHLORPROPAMIDE (USP-RS)
CHLORPROPAMIDE [USP-RS]
Chlorpropamidum [INN-Latin]
Clorpropamida [INN-Spanish]
CHLORPROPAMIDE (EP IMPURITY)
CHLORPROPAMIDE [EP IMPURITY]
CHLORPROPAMIDE (USP MONOGRAPH)
CHLORPROPAMIDE [USP MONOGRAPH]
Diabinese (TN)
CCRIS 155
1-(p-Chlorobenzensulfonyl)-3-propylurea
HSDB 2051
4-chloro-n-(propylaminocarbonyl)benzenesulfonamide
SR-01000000060
4-chloro-N-((propylaminocarbonyl)benzenesulfonamide
EINECS 202-314-5
UNII-WTM2C3IL2X
U-3818
NSC 626720
BRN 2218363
Diabinase
Urea, 1-((p-chloropenyl)sulfonyl)-3-propyl-
Prestwick_684
Chlorpropamide [USP:INN:BAN:JAN]
Spectrum_000144
1-(4-chlorophenyl)sulfonyl-3-propyl-urea
Opera_ID_359
Prestwick0_000323
Prestwick1_000323
Prestwick2_000323
Prestwick3_000323
Spectrum2_000089
Spectrum3_000347
Spectrum4_000284
Spectrum5_000719
WLN: GR DSWMVM3
Chlorpropamide (Standard)
Lopac-C-1290
chlorpropamide, delta-form
1-(4-chloro-benzenesulfonyl)-3-n-propyl-urea
C 1290
CHLORPROPAMIDE [MI]
CHLORPROPAMIDE [INN]
CHLORPROPAMIDE [JAN]
Lopac0_000229
SCHEMBL23947
BSPBio_000325
BSPBio_002013
CHLORPROPAMIDE [HSDB]
KBioGR_000808
KBioGR_002273
KBioSS_000624
KBioSS_002274
MLS001148665
CHLORPROPAMIDE [VANDF]
DivK1c_000513
SPECTRUM1500185
SPBio_000018
SPBio_002246
BPBio1_000359
GTPL6801
CHLORPROPAMIDE [WHO-DD]
HMS501J15
HY-B1429R
KBio1_000513
KBio2_000624
KBio2_002273
KBio2_003192
KBio2_004841
KBio2_005760
KBio2_007409
KBio3_001233
KBio3_002753
Chlorpropamide (JP18/USP/INN)
cMAP_000007
NINDS_000513
HMS1569A07
HMS1920M05
HMS2091E08
HMS2096A07
HMS2233L19
HMS3259A17
HMS3260N19
HMS3373D09
HMS3428C03
HMS3652L03
HMS3713A07
Pharmakon1600-01500185
BCP09162
HY-B1429
CHLORPROPAMIDE [ORANGE BOOK]
Tox21_110102
Tox21_201391
Tox21_302789
Tox21_500229
AC8695
BDBM50344965
CCG-38905
NSC756690
NSC813219
s4166
STK857458
AKOS001482739
Tox21_110102_1
CS-4917
DB00672
KS-5316
LP00229
NC00503
NSC-756690
NSC-813219
SDCCGSBI-0050217.P005
IDI1_000513
MRF-0000539
NCGC00015216-01
NCGC00015216-02
NCGC00015216-03
NCGC00015216-04
NCGC00015216-05
NCGC00015216-06
NCGC00015216-07
NCGC00015216-08
NCGC00015216-09
NCGC00015216-10
NCGC00015216-12
NCGC00015216-13
NCGC00015216-14
NCGC00015216-17
NCGC00015216-18
NCGC00015216-23
NCGC00021451-03
NCGC00021451-04
NCGC00021451-05
NCGC00021451-06
NCGC00021451-07
NCGC00021451-08
NCGC00256414-01
NCGC00258942-01
NCGC00260914-01
DA-72183
SY052508
SBI-0050217.P004
AB00051944
C1220
Chlorpropamide, analytical standard, >=97%
EU-0100229
NS00005378
P-607
SW196839-3
D00271
U 9818
Urea, 1-propyl-3-(p-chloro-benzenesulfonyl)-
AB00051944_16
AB00051944_17
EN300-7388134
Q1075324
SR-01000000060-2
SR-01000000060-4
SR-01000000060-6
4-Chloro-N-[(propylamino)-carbonyl]benzenesulfonamide
BRD-K97746869-001-05-6
BRD-K97746869-001-15-5
BRD-K97746869-001-26-2
BRD-K97746869-001-27-0
Z276509110
1-Chloro-4-(([(propylamino)carbonyl]amino)sulfonyl)benzene #
Chlorpropamide, European Pharmacopoeia (EP) Reference Standard
Chlorpropamide, United States Pharmacopeia (USP) Reference Standard
Chlorpropamide, Pharmaceutical Secondary Standard; Certified Reference Material
202-314-5
Solubility of 1-(4-chlorophenyl)sulfonyl-3-propyl-urea (C10H13ClN2O3S)
The solubility of 1-(4-chlorophenyl)sulfonyl-3-propyl-urea can be influenced by various factors, including temperature, pH, and the nature of the solvent used. This compound, bearing both sulfonyl and urea functional groups, presents interesting solubility characteristics:
In practical applications, understanding the solubility profile of 1-(4-chlorophenyl)sulfonyl-3-propyl-urea is essential for its formulation in various chemical processes and treatments. Overall, while its solubility may vary widely depending on the conditions, the outlined factors play a crucial role in determining its behavior in different solvents.