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Carvedilol

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Identification
Molecular formula
C24H26N2O3
CAS number
72956-09-3
IUPAC name
1-(4-cyclohexylphenoxy)-3-[4-(2-pyridyl)piperazin-1-yl]propan-2-ol
State
State

At room temperature, carvedilol is in a solid state.

Melting point (Celsius)
114.00
Melting point (Kelvin)
387.15
Boiling point (Celsius)
479.15
Boiling point (Kelvin)
752.30
General information
Molecular weight
406.49g/mol
Molar mass
406.4860g/mol
Density
1.1604g/cm3
Appearence

Carvedilol is a white to off-white crystalline powder that is practically insoluble in water. It is commonly used in its racemic form.

Comment on solubility

Solubility of 1-(4-cyclohexylphenoxy)-3-[4-(2-pyridyl)piperazin-1-yl]propan-2-ol

The compound 1-(4-cyclohexylphenoxy)-3-[4-(2-pyridyl)piperazin-1-yl]propan-2-ol, with the chemical formula C24H26N2O3, exhibits interesting solubility characteristics that are influenced by its structural components. Understanding the solubility of this compound is essential for its potential applications, especially in pharmaceutical contexts.

Factors Influencing Solubility

The solubility of this compound can be affected by several factors, including:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents.
  • Molecular weight: Higher molecular weights may lead to decreased solubility.
  • Hydrophobic regions: The cyclohexyl group contributes to hydrophobicity, impacting solubility in nonpolar solvents.

Solvent Compatibility

This compound is expected to display varying solubility across different solvents:

  • Water: Limited solubility due to its hydrophobic characteristics.
  • Organic solvents: Soluble in organic solvents such as ethanol and methanol, facilitating its use in organic synthesis.

In summary, the solubility of 1-(4-cyclohexylphenoxy)-3-[4-(2-pyridyl)piperazin-1-yl]propan-2-ol is multifaceted and underscores the importance of understanding the polarity, molecular interactions, and the nature of solvents to optimize its use in various applications.

Interesting facts

Interesting Facts about 1-(4-cyclohexylphenoxy)-3-[4-(2-pyridyl)piperazin-1-yl]propan-2-ol

This intriguing compound, known for its complex structure and diverse applications, showcases the fascinating interplay between chemistry and medicinal science. Here are some captivating details:

  • Pharmacological Importance: 1-(4-cyclohexylphenoxy)-3-[4-(2-pyridyl)piperazin-1-yl]propan-2-ol is part of a class of compounds that have shown potential in the field of pharmaceuticals, especially in the treatment of psychiatric disorders.
  • Structural Diversity: The molecule features a distinctive assembly of functional groups, including a cyclohexylphenoxy moiety and a piperazine ring. This structural diversity is key to its biological activity and can influence its binding affinity and selectivity for various receptors.
  • Mechanism of Action: Compounds like this one often target neurotransmitter systems in the brain, particularly serotonin and dopamine pathways, which are crucial for mood regulation and cognitive function.
  • Research and Development: Ongoing research explores the compound's potential in drug development, where modifications to its structure can lead to improved efficacy or reduced side effects.
  • Synthetic Challenge: The synthesis of such complex organic molecules often requires advanced techniques and reagents, highlighting the innovative nature of modern synthetic organic chemistry.

In conclusion, 1-(4-cyclohexylphenoxy)-3-[4-(2-pyridyl)piperazin-1-yl]propan-2-ol serves as a rich subject for study within pharmaceutical chemistry, where its unique attributes may pave the way for new therapeutic avenues.

Synonyms
sdz 35-682
CHEBI:45666
1-(4-cyclohexylphenoxy)-3-[4-(pyridin-2-yl)piperazin-1-yl]propan-2-ol
1-(4-cyclohexylphenoxy)-3-(4-pyridin-2-ylpiperazin-1-yl)propan-2-ol
1-(2-hydroxy-3-(4-cyclohexylphenoxy)propyl)-4-(2-pyridyl)piperazine
1-(4-cyclohexylphenoxy)-3-(4-(pyridin-2-yl)piperazin-1-yl)propan-2-ol
SCHEMBL14191675
SCHEMBL21067682
SDZ-35-682
PD036808
Q27120617
1-(4-cyclohexylphenoxy)-3-[4-(2-pyridyl)piperazin-1-yl]propan-2-ol
1-Piperazineethanol, alpha-[(4-cyclohexylphenoxy)methyl]-4-(2-pyridinyl)-