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Isoproterenol

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Identification
Molecular formula
C13H19NO
CAS number
5984-95-2
IUPAC name
1-(4-cyclopropylphenyl)-2-(isopropylamino)ethanol
State
State

At room temperature, isoproterenol is typically in a solid state, specifically as a crystalline powder. This is due to its molecular structure and intermolecular interactions that keep it in this form under standard conditions.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
320.00
Boiling point (Kelvin)
593.15
General information
Molecular weight
211.30g/mol
Molar mass
211.3010g/mol
Density
1.0130g/cm3
Appearence

Isoproterenol typically appears as a white to off-white crystalline powder. It is often supplied in the form of a hydrochloride salt, which is also white or off-white in color. The compound is known for its characteristic pharmaceutical appearance when processed into medications.

Comment on solubility

Solubility of 1-(4-cyclopropylphenyl)-2-(isopropylamino)ethanol

The solubility of the compound 1-(4-cyclopropylphenyl)-2-(isopropylamino)ethanol can be characterized by several key factors:

  • Polarity: The presence of both hydroxyl (-OH) and amine (-NH) functional groups suggests that this compound is likely to exhibit polar characteristics, which generally increases solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the hydroxyl group can enhance solubility in aqueous environments. Molecules capable of such interactions tend to dissolve better in water.
  • Size and Structure: The bulky cyclopropyl group may impact overall solubility. Generally, larger and more complex structures can decrease solubility due to steric hindrance, although this is countered by polar functional groups.

It is important to note how solubility can impact the compound’s pharmacological properties and bioavailability. Enhanced solubility allows for better absorption in biological systems, which is vital for drug development.

In summary, 1-(4-cyclopropylphenyl)-2-(isopropylamino)ethanol possesses characteristics that may lead to increased solubility in polar solvents, primarily due to the presence of functional groups that can engage in hydrogen bonding. However, the specific solubility profile may require experimental determination for precise applications.

Interesting facts

Interesting Facts about 1-(4-cyclopropylphenyl)-2-(isopropylamino)ethanol

1-(4-cyclopropylphenyl)-2-(isopropylamino)ethanol is an intriguing compound that belongs to the class of β-adrenergic antagonists, often used in pharmacological and biochemical studies. This compound has gained attention due to its potential applications in treating various cardiovascular conditions, making it a significant focus of research.

Key Features:

  • Structure: This compound features a cyclopropylphenyl group that introduces unique stereochemical properties, influencing its pharmacokinetics and affinity for β-adrenergic receptors.
  • Mechanism of Action: By acting as an antagonist at β-adrenergic receptors, it can help manage symptoms associated with hypertension and other heart-related issues.
  • Research Applications: Scientists study this compound to understand better the interactions between adrenergic receptors and various ligands, contributing to drug development in cardiology.
  • Synthetic Pathways: The synthesis of this compound can involve several interesting chemical reactions, including amine coupling and cyclization processes, which provide an excellent opportunity for students to explore organic synthesis techniques.

Moreover, the cyclopropyl group, contributing to the steric effects and electronic characteristics of the compound, exemplifies the importance of molecular structure in drug design. As noted by researchers, “The substitution patterns on aromatic rings can greatly influence the biological activity of compounds." This highlights the continuous pursuit of scientists to fine-tune and optimize drug candidates for maximum efficacy and minimal side effects.

In conclusion, 1-(4-cyclopropylphenyl)-2-(isopropylamino)ethanol holds a vital position in medicinal chemistry, representing the intricate balance between structure and function in pharmaceutical development.

Synonyms
AKOS018536613