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Daraprim

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Identification
Molecular formula
C12H13N3O3S
CAS number
58-14-0
IUPAC name
1-[[4-(dimethylamino)phenyl]methyleneamino]-3-[(5-nitro-2-furyl)methyleneamino]urea
State
State

At room temperature, Daraprim is typically solid.

Melting point (Celsius)
231.00
Melting point (Kelvin)
504.00
Boiling point (Celsius)
245.00
Boiling point (Kelvin)
518.15
General information
Molecular weight
348.35g/mol
Molar mass
348.3500g/mol
Density
1.3400g/cm3
Appearence

Daraprim appears as a white to yellowish, crystalline powder. It is practically odorless and has a bitter taste.

Comment on solubility

Solubility of 1-[[4-(dimethylamino)phenyl]methyleneamino]-3-[(5-nitro-2-furyl)methyleneamino]urea

The solubility of 1-[[4-(dimethylamino)phenyl]methyleneamino]-3-[(5-nitro-2-furyl)methyleneamino]urea can be influenced by its molecular structure and functional groups. Here are some key points regarding its solubility:

  • Polar vs Nonpolar Characteristics: The presence of the dimethylamino and nitro groups suggests a degree of polarity, which typically enhances solubility in polar solvents like water.
  • Hydrogen Bonding: The urea functional group facilitates hydrogen bonding, which can further increase the compound's affinity for aqueous environments.
  • Solvation Effects: The ability of solvent molecules to solvate the compound significantly affects solubility; for instance, polar solvents may solvate the dimethylamino group effectively.
  • Temperature Dependence: The solubility may vary with temperature, as increased kinetic energy can aid in solute-solvent interactions.

In conclusion, while precise solubility data for this specific compound may be limited, it is likely to exhibit improved solubility in polar solvents due to its functional groups and potential for hydrogen bonding. The unique structural attributes present in 1-[[4-(dimethylamino)phenyl]methyleneamino]-3-[(5-nitro-2-furyl)methyleneamino]urea suggest interesting solubility behavior that would be fascinating to explore through empirical studies.

Interesting facts

Interesting Facts about 1-[[4-(dimethylamino)phenyl]methyleneamino]-3-[(5-nitro-2-furyl)methyleneamino]urea

This intriguing compound, known as 1-[[4-(dimethylamino)phenyl]methyleneamino]-3-[(5-nitro-2-furyl)methyleneamino]urea, showcases a complex structure that includes both aromatic and heterocyclic components, making it a subject of interest in areas such as organic chemistry and medicinal research.

Chemical Structure and Properties

The unique features of this compound include:

  • Aromatic Systems: The presence of a phenyl group and a furan ring contributes to the compound's chemical reactivity and potential interactions with biological systems.
  • Dimethylamino Group: The dimethylamino moiety can enhance the compound's solubility and bioavailability, which are crucial factors in drug design.
  • Nitro Group: The nitro substituent is known for its electron-withdrawing properties, influencing the reactivity of the compound and its interaction with various biological targets.

Potential Applications

Research has suggested that compounds like this may have applications in:

  • Pharmaceuticals: Due to their structural complexity, such compounds often display biological activity, making them potential candidates for drug development.
  • Organic Synthesis: The reactive functional groups present can facilitate various synthetic pathways, rendering this compound useful in creating more complex molecules.

As stated by renowned chemist, "The beauty of organic chemistry lies in the vast possibilities that arise from simple changes in molecular structure," highlighting the significance of compounds like this in advancing our understanding and application of chemistry.

Ultimately, 1-[[4-(dimethylamino)phenyl]methyleneamino]-3-[(5-nitro-2-furyl)methyleneamino]urea exemplifies the richness of chemical diversity and its role in shaping future innovations in various fields.