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Berbamine

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Identification
Molecular formula
C32H39NO6
CAS number
478-61-5
IUPAC name
1-[(4-ethoxy-3-methoxy-phenyl)methyl]-6,7-dimethoxy-3-methyl-isoquinoline
State
State

At room temperature, berbamine is in a solid state. It is typically handled as a powder and stored in a dry, cool place to maintain its stability.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
695.20
Boiling point (Kelvin)
968.30
General information
Molecular weight
368.44g/mol
Molar mass
368.4370g/mol
Density
1.2659g/cm3
Appearence

Berbamine appears as a white to off-white crystalline powder. It is typically odorless and is well-known in the chemical community for its applications in biological research.

Comment on solubility

Solubility Insights of 1-[(4-ethoxy-3-methoxy-phenyl)methyl]-6,7-dimethoxy-3-methyl-isoquinoline

The solubility of 1-[(4-ethoxy-3-methoxy-phenyl)methyl]-6,7-dimethoxy-3-methyl-isoquinoline can be quite intriguing, especially considering its complex structure. Understanding its solubility characteristics is essential for various applications in fields such as pharmaceuticals and chemistry.

Factors Affecting Solubility:

  • Polarity: This compound contains various methoxy and ethoxy groups, which can influence its polar character. Increased polarity can lead to improved solubility in polar solvents.
  • Hydrophobic Interactions: The isoquinoline core and the aromatic rings may exhibit hydrophobic interactions, affecting its solubility in aqueous environments.
  • Solvent Type: Solubility can vary significantly depending on whether the solvent is organic or aqueous. It is typically expected to have higher solubility in organic solvents due to its structural features.

In practical terms, while specific solubility data might not be readily available, one can often approximate its behavior in various solvents through experimental studies. It is common for structurally similar compounds to exhibit variable solubility patterns, influenced by the precise arrangement of functional groups.

Conclusion:

In summary, the solubility of 1-[(4-ethoxy-3-methoxy-phenyl)methyl]-6,7-dimethoxy-3-methyl-isoquinoline is likely to be nuanced and multifaceted. Conducting specific solubility experiments will yield more insightful information, making it crucial for researchers working with this compound to explore solubility in diverse solvent environments.

Interesting facts

1-[(4-Ethoxy-3-methoxy-phenyl)methyl]-6,7-dimethoxy-3-methyl-isoquinoline

This compound, belonging to the isoquinoline family, is fascinating not only for its structural complexity but also for its potential applications in various fields of research. Isoquinolines are known for their diverse biological activities, making them significant in medicinal chemistry.

Interesting Attributes:

  • Bioactivity: Compounds like this one have been explored for their potential anti-cancer and anti-inflammatory properties.
  • Structural Diversity: The presence of multiple methoxy and ethoxy groups enhances the compound's versatility, allowing for variations in chemical reactivity.
  • Pharmacophore Landscape: The unique arrangement of functional groups can lead to interactions with biological targets, making it a subject of interest for drug design.

Research studies have shown that derivatives of isoquinoline exhibit various pharmacological effects, including antimicrobial and neuroprotective activities. According to scientific literature, "the modifications on the isoquinoline scaffold, such as alkyl substitutions, significantly impact the biological activities of these compounds." This compound could very well be at the forefront of new therapeutic developments.

Potential Applications:

  • Development of new pharmaceuticals targeting specific diseases.
  • Utilization in organic synthesis as a building block for larger complex molecules.
  • Role in materials science due to its interesting electronic properties.

As research continues, the compound's properties and potential uses are expected to unfold further, revealing its significance in not just synthetic chemistry, but also in real-world applications in the field of medicine and beyond.

Synonyms
Dimoxyline
Dioxyline
147-27-3
Dimoxyline [INN]
Dimossilina
Dimoxilinio
Dimoxylinum
Dimossilina [DCIT]
dimoxilina
Dimoxylinum [INN-Latin]
UNII-46X4C9TILS
Dimoxilinio [INN-Spanish]
46X4C9TILS
1-[(4-ethoxy-3-methoxyphenyl)methyl]-6,7-dimethoxy-3-methylisoquinoline
DIMOXYLINE [MI]
1-(4-Ethoxy-3-methoxybenzyl)-6,7-dimethoxy-3-methylisoquinoline
DIMOXYLINE [WHO-DD]
DTXSID10163559
L 08146
Dimoxylinum (INN-Latin)
Dimoxilinio (INN-Spanish)
6,7-DIMETHOXY-1-(4'-ETHOXY-3'-METHOXYBENZYL)-3-METHYLISOQUINOLINE
6,7-DIMETHOXY-3-METHYL-1-(3'-METHOXY-4'-ETHOXYBENZYL)ISOQUINOLINE
1-((4-ethoxy-3-methoxyphenyl)methyl)-6,7-dimethoxy-3-methylisoquinoline
DTXCID0086050
dioxyline (tn)
dioxyline (van)
SCHEMBL555298
CHEMBL2105041
CHEBI:135548
AKOS040751584
NS00123718
Q27258964