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4-Fluoroamphetamine

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Identification
Molecular formula
C11H14FN
CAS number
459-02-9
IUPAC name
1-(4-fluoro-1H-indol-3-yl)propan-2-amine
State
State
4-Fluoroamphetamine is typically found as a solid at room temperature, which can be formed into powder or crystals for practical use.
Melting point (Celsius)
151.00
Melting point (Kelvin)
424.15
Boiling point (Celsius)
220.00
Boiling point (Kelvin)
493.15
General information
Molecular weight
167.24g/mol
Molar mass
167.2080g/mol
Density
1.2100g/cm3
Appearence

4-Fluoroamphetamine appears as either a crystalline solid or powder. It is typically colorless to white in appearance, but its exact appearance can vary depending on the specific preparation and purity. Any impurities might potentially alter its color slightly.

Comment on solubility

Solubility of 1-(4-fluoro-1H-indol-3-yl)propan-2-amine

The solubility of 1-(4-fluoro-1H-indol-3-yl)propan-2-amine in various solvents can be quite intriguing due to its unique molecular structure. Here are some key considerations regarding its solubility:

  • Polar Solvents: Compounds with amine groups often exhibit higher solubility in polar solvents such as water. The presence of the amine functional group allows for hydrogen bonding, enhancing its solubility.
  • Non-Polar Solvents: On the contrary, its solubility in non-polar solvents is typically limited. The indole ring and the fluorine substitution may also influence the overall hydrophobic character of the compound.
  • Temperature Effects: As with many organic compounds, solubility can be temperature-dependent. Increasing the temperature may enhance solubility due to increased molecular motion.
  • Industry Implications: Understanding solubility is crucial for applications in pharmaceuticals, as solubility directly impacts bioavailability

In conclusion, while 1-(4-fluoro-1H-indol-3-yl)propan-2-amine shows promising solubility characteristics in polar solvents due to its amine structure, its overall functionality and behavior in various mixtures necessitate further exploration. The intricate balance of its polar and non-polar features is what makes the study of its solubility both challenging and fascinating!

Interesting facts

Exploring 1-(4-fluoro-1H-indol-3-yl)propan-2-amine

1-(4-fluoro-1H-indol-3-yl)propan-2-amine, often referred to as a component in the realm of pharmacology and medicinal chemistry, carries unique structural and functional attributes that intrigue both scientists and researchers alike. Here are some notable aspects of this compound:

  • Structural Diversity: This compound features an indole ring, which is a common motif in many natural products and pharmaceuticals. The presence of the fluorine atom enhances its lipophilicity and biological activity.
  • Biological Activity: Compounds similar to this one are studied for their potential *psychoactive effects*. They are often associated with serotonin receptor interactions, which can play crucial roles in mood regulation.
  • Applications in Research: The compound is significant in the synthesis of various analogs that could serve therapeutic roles. Researchers often explore its derivatives for potential use in treating mood disorders.
  • Fluorine Modification: The introduction of a fluorine atom can dramatically alter the physicochemical properties of organic compounds, making them more suitable for drug formulation due to improved metabolic stability.
  • Significance in Drug Design: Understanding the pharmacokinetic profile of indole derivatives helps in designing better drugs with improved efficacy and reduced side effects.

In conclusion, 1-(4-fluoro-1H-indol-3-yl)propan-2-amine exemplifies the fascinating interplay between structure and function in organic chemistry, highlighting its potential importance in therapeutic applications. As research continues, the implications of this compound in the medical field may offer new insights into cognitive health and treatment methodologies.

Synonyms
1-(4-fluoro-1H-indol-3-yl)propan-2-amine
23130-91-8
SCHEMBL20503285
AKOS006304789
EN300-359763