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4-Fluorophenylpiperazinylbutanone

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Identification
Molecular formula
C20H23FN2O
CAS number
625446-73-3
IUPAC name
1-(4-fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one
State
State

This compound is a solid at room temperature, typically existing as a crystalline powder.

Melting point (Celsius)
172.00
Melting point (Kelvin)
445.15
Boiling point (Celsius)
452.50
Boiling point (Kelvin)
725.65
General information
Molecular weight
329.40g/mol
Molar mass
329.3980g/mol
Density
1.2000g/cm3
Appearence

4-Fluorophenylpiperazinylbutanone is typically a solid compound that can appear as a crystalline powder. The color of this powder is often white to off-white, which is common for many organic compounds that are synthesized for pharmaceuticals.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one

The solubility of 1-(4-fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one in various solvents is a key factor in its potential applications and effectiveness in formulations. Based on the structural features of this compound, we can draw some insights regarding its solubility properties:

  • Polarity: The presence of polar substituents, such as the piperazine group and the fluorophenyl moiety, suggests that the compound may exhibit some degree of polar solubility, particularly in polar solvents like methanol and ethanol.
  • Hydrophobic Character: The hydrophobic phenyl groups contribute to a degree of insolubility in purely polar solvents; therefore, the compound could also display reasonable solubility in non-polar solvents, such as chloroform and dichloromethane.
  • pH Sensitivity: The solubility may also be influenced by the pH of the solution, as the piperazine ring can become protonated in acidic environments, potentially enhancing solubility in aqueous conditions.
  • Practical Implications: Understanding its solubility behavior is essential for determining optimal conditions for drug formulation, bioavailability, and therapeutic efficacy.

In summary, the solubility of 1-(4-fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one is expected to vary widely based on solvent choice and environmental conditions, thus necessitating comprehensive solubility studies to identify favorable conditions for its intended applications.

Interesting facts

Interesting Facts about 1-(4-fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one

1-(4-fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one, commonly referred to in research as a psychoactive substance, has garnered attention in the field of medicinal chemistry and neuroscience. Here are some intriguing aspects of this compound:

  • Psychoactive Properties: This compound exhibits effects that can alter mood and perception, making it a subject of study in the potential treatment of various psychological conditions.
  • Structure-Activity Relationship: The presence of both the 4-fluorophenyl and the 4-phenylpiperazin moieties plays a critical role in defining its pharmacological profile.
  • Receptor Affinity: Its affinity for different neurotransmitter receptors is an area of ongoing research, particularly focusing on serotonin and dopamine receptors.
  • Safety and Legality: As a novel compound, its legal status may vary across different jurisdictions, and it is crucial for researchers to stay updated on regulations regarding its use.

According to one study, researchers noted, “Understanding the interaction of such compounds with brain receptors may open up new avenues for treatment.” This highlights the potential of 1-(4-fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one as a valuable asset in pharmaceutical development.

As a chemist or student excited about the intersection of chemistry and pharmacology, the study of this compound not only enhances our understanding of drug design but also paves the way for innovative therapeutic strategies.

Synonyms
MLS002703965
NSC107348
CHEMBL1714502
NSC-107348
SMR001570676