Interesting facts
Interesting Facts about 1-(4-fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one; dihydrochloride
This compound, known for its complex structure and application in medicinal chemistry, is of significant interest in the development of pharmaceuticals. Here are some intriguing aspects:
- Pharmacological Relevance: This compound is often investigated for its potential use in treating central nervous system disorders. Its unique molecular structure allows it to interact with neurotransmitter systems in the brain.
- Structure Activity Relationship (SAR): The presence of the 4-fluorophenyl and 4-phenylpiperazine moieties plays a crucial role in modulating the compound's pharmacological effects. Understanding how these groups influence activity is essential for drug design.
- Research Interest: Scientists are particularly interested in this compound due to its potential anti-anxiety and antidepressant properties. Research studies often focus on how modifications to its structure can enhance efficacy or reduce side effects.
- Synthetic Pathways: The synthesis of this compound involves several intricate steps, making it a popular subject for studies in organic chemistry and synthetic methods. Each step provides insight into reaction mechanisms and the reactivity of functional groups.
- Emphasis on Dihydrochloride Form: The dihydrochloride salt form improves solubility and stability, which is critical for drug formulation. Understanding the behavior of salts can significantly impact the compound's application in therapeutic settings.
This compound exemplifies the intricate relationship between chemical structure and biological activity, showcasing the importance of interdisciplinary approaches in modern medicinal chemistry research.
Synonyms
27922-14-1
BUTYROPHENONE, 4'-FLUORO-3-(4-PHENYL-1-PIPERAZINYL)-, DIHYDROCHLORIDE
RefChem:1080514
4'-Fluoro-3-(4-phenyl-1-piperazinyl)butyrophenone dihydrochloride
DTXSID80950599
1-(4-Fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one--hydrogen chloride (1/2)
Solubility of 1-(4-fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one; dihydrochloride
The solubility of the compound 1-(4-fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one; dihydrochloride can be influenced by several factors due to its unique structural characteristics. Being a dihydrochloride salt, it is generally more soluble in aqueous solutions compared to its base form. The presence of the two hydrochloride groups enhances its ionic character, leading to improved solubility in water.
Key points to consider:
In summary, the solubility of 1-(4-fluorophenyl)-3-(4-phenylpiperazin-1-yl)butan-1-one; dihydrochloride is generally favorable in polar solvents like water, making it suitable for pharmaceutical applications and further research. As studies suggest, understanding solubility is crucial for the compound's efficacy and bioavailability.