4'-Fluorobutyryl fentanyl hydrochloride

Interesting Facts about 1-(4-Fluorophenyl)-3-piperidin-1-ium-1-yl-butan-1-one; Chloride

This compound, often referred to as a member of the piperidine derivatives, holds intriguing importance in both medicinal chemistry and material science. Here are some remarkable facts:

• Structural Features: The presence of a 4-fluorophenyl group enhances lipophilicity, which can significantly influence the compound's biological activity. This substitution pattern is known to affect pharmacokinetics and can bolster interaction with biological targets.
• Therapeutic Potential: Compounds containing piperidine moieties are often explored for their antidepressant, antipsychotic, and analgesic properties. This makes them invaluable in the field of drug development.
• Research Applications: Beyond pharmacology, this compound can function as a building block for synthesizing more complex molecules, making it useful in organic synthesis and medicinal chemistry.
• Salting Out Effect: The chloride component helps in enhancing solubility in polar solvents, thereby affecting how it interacts in various chemical environments.
• Fluorine’s Role: The fluorine atom not only modifies the hydrophobicity but also contributes to the stability and activity of the compound, a phenomenon that is particularly well studied in drug design.

In summary, 1-(4-fluorophenyl)-3-piperidin-1-ium-1-yl-butan-1-one; chloride serves as an excellent example of how subtle modifications in chemical structure can lead to significant changes in both function and utility. As researchers continue to explore such compounds, new therapeutic avenues and innovative applications will undoubtedly emerge.