Skip to main content

Bupropion

ADVERTISEMENT
Identification
Molecular formula
C13H17ClNO
CAS number
34841-39-9
IUPAC name
1-(4-fluorophenyl)-4-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)butan-1-one
State
State

Bupropion is commonly in a solid state at room temperature.

Melting point (Celsius)
238.00
Melting point (Kelvin)
511.15
Boiling point (Celsius)
327.30
Boiling point (Kelvin)
600.45
General information
Molecular weight
239.74g/mol
Molar mass
239.7370g/mol
Density
1.0132g/cm3
Appearence

Bupropion is typically a white crystalline powder.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)butan-1-one

The solubility of 1-(4-fluorophenyl)-4-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)butan-1-one can be quite fascinating, as it involves a complex organic structure that may influence its interaction with various solvents. Understanding its solubility is essential for applications in pharmaceuticals and organic chemistry.

Factors Affecting Solubility

Several key factors can influence the solubility of this compound:

  • Polarity: The presence of both hydrophobic regions (due to the aromatic and bicyclic structure) and polar functional groups can lead to varying solubility in polar and nonpolar solvents.
  • Hydrogen Bonding: If the compound can engage in hydrogen-bonding interactions, it may enhance solubility in polar solvents like water or alcohols.
  • Temperature: Generally, increasing temperature can increase solubility, particularly for solid compounds in liquids.

Expected Solubility Behavior

While precise solubility data for this compound may be limited, one can anticipate:

  • Higher solubility in organic solvents such as acetone and methanol due to its structural characteristics.
  • Lower solubility in water since the hydrophobic nature may dominate, complicating dissolution in polar solvents.

In conclusion, the solubility of 1-(4-fluorophenyl)-4-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)butan-1-one is influenced by its unique molecular attributes, and further experimental studies would be valuable to determine the exact solubility profile. As always, "solubility is a dance between the solute and solvent," influenced by their respective polarities and interactions.

Interesting facts

Interesting Facts about 1-(4-fluorophenyl)-4-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)butan-1-one

This compound is a fascinating example of the diversity found within organic chemistry, particularly in the realm of psychoactive substances. Its structure suggests it belongs to a class of compounds that may influence the central nervous system due to its unique pharmacophore configuration.

Key Features

  • Fluorine Substitution: The presence of a fluorine atom in the para position of the phenyl ring can significantly alter the compound’s biological activity, impacting its potency and metabolic stability.
  • 3-Azabicyclo Framework: The bicyclic structure is not only intriguing from a synthetic chemistry standpoint but also plays a role in the compound's interaction with neuronal receptors. Bicyclic compounds are often pivotal in drug design, providing a window into the synergy between structure and function.
  • Potential Applications: Compounds like this one are of great interest for their potential applications in treating neurological disorders, including but not limited to anxiety and depression. Research continues to uncover their role in neurochemistry.

Scientific Insights

As noted by researchers in the field, "The delicate balance of molecular interactions determines the efficacy of compounds in neurological therapies." This highlights the importance of the compound's spatial arrangement, which can be fine-tuned through synthetic approaches.

Additionally, the stereochemical aspects of this compound could lead to enantiomers with vastly different biological profiles, which is a fascinating consideration for drug development. The exploration of these variations represents a significant area of ongoing research, as scientists aim to refine therapeutic profiles while minimizing side effects.

In conclusion, 1-(4-fluorophenyl)-4-(1,8,8-trimethyl-3-azabicyclo[3.2.1]octan-3-yl)butan-1-one embodies a rich tapestry of opportunities for discovery in chemical and pharmaceutical sciences, serving as a reminder of the intricate dance between structure and function in organic chemistry.