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4'-fluorofentanyl

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Identification
Molecular formula
C24H30FN1O1
CAS number
78995-14-9
IUPAC name
1-(4-fluorophenyl)-4-[4-(1-piperidyl)-4-propanoyl-1-piperidyl]butan-1-one
State
State

4'-fluorofentanyl is typically a solid at room temperature. It is often found in a crystalline powder form but may also be encountered in pressed tablets.

Melting point (Celsius)
87.00
Melting point (Kelvin)
360.20
Boiling point (Celsius)
318.90
Boiling point (Kelvin)
592.10
General information
Molecular weight
336.43g/mol
Molar mass
336.4320g/mol
Density
1.2000g/cm3
Appearence

4'-fluorofentanyl typically appears as a white to off-white crystalline powder. The compound may also be found in solid forms such as tablets. As with many fentanyl analogs, it can be finely powdered, which is characteristic of many pharmaceutical-grade narcotics.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-[4-(1-piperidyl)-4-propanoyl-1-piperidyl]butan-1-one

The solubility of 1-(4-fluorophenyl)-4-[4-(1-piperidyl)-4-propanoyl-1-piperidyl]butan-1-one in various solvents can provide critical insights into its behavior in biological and chemical systems. This compound's solubility characteristics can be influenced by several factors:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents, while non-polar sections might favor solubility in non-polar solvents.
  • Temperature: Increased temperature often leads to greater solubility due to enhanced molecular motion and solvent interactions.
  • pH Levels: The ionization of certain functional groups at varying pH levels can significantly affect the solubility.

In practical terms, the solubility of this compound is likely to vary across different solvents. It may exhibit higher solubility in organic solvents such as DMSO or ethanol compared to water, based on its molecular structure. Understanding the solubility can assist in determining optimal conditions for synthesis and application, emphasizing that solubility is a key property that governs the usability of chemical compounds in various fields.

Interesting facts

Interesting Facts About 1-(4-Fluorophenyl)-4-[4-(1-Piperidyl)-4-Propanoyl-1-Piperidyl]Butan-1-One

This chemical compound, known for its intricate structure, falls under the category of substituted diketones. The unique combination of phenyl and piperidyl groups contributes to its interesting properties and potential applications.

Key Features:

  • Pharmacological Relevance: This compound has been noted for its potential therapeutic applications, particularly in the field of neuroscience and psychiatry. Its piperidyl structures hint at affinities for various receptors.
  • Synthesis: The synthesis of this compound typically involves a multi-step organic reaction process. Chemists often use various coupling reactions and protective group strategies to achieve the desired functionality and purity.
  • Research Focus: Its unique structure has attracted attention for research into the mechanisms of action and the development of novel medicinal agents.
  • Functional Groups: The combination of functional groups, particularly the fluorophenyl and the diketone moiety, makes this compound a subject of interest for studying molecular interactions.

As expressed by chemist Robert H. Grubbs, "In chemistry, the smaller a change, the greater impact it can have on the properties of a compound." The subtle modifications in this compound's structure can vastly influence its biological interactions and activity levels.

Overall, 1-(4-fluorophenyl)-4-[4-(1-piperidyl)-4-propanoyl-1-piperidyl]butan-1-one stands as a compelling example of how complex molecules can pave the way for advancements in medical chemistry and therapeutic development.

Synonyms
Propyperone
Floropipeton
Propiperona
Propyperone [INN]
3781-28-0
Propyperonum
Propyperonum [INN-Latin]
Propiperona [INN-Spanish]
R 4082
UNII-HG22108KQK
BRN 0495940
HG22108KQK
R-4082
4'-Fluoro-4-(4-piperidino-4-propionylpiperidino)butyrophenone
DTXSID50191250
5-22-12-00490 (Beilstein Handbook Reference)
BUTYROPHENONE, 4'-FLUORO-4-(4-PIPERIDINO-4-PROPIONYLPIPERIDINO)-
Propyperonum (INN-Latin)
Propiperona (INN-Spanish)
1-Butanone, 1-(4-fluorophenyl)-4-(4'-(1-oxopropyl)(1,4'-bipiperidin)-1'-yl)-
DTXCID60113741
1-Butanone, 1-(4-fluorophenyl)-4-(4'-(1-oxopropyl)(1,4'-bipiperidin)-1'-yl)-(9CI)
1-(4-fluorophenyl)-4-(4-piperidin-1-yl-4-propanoylpiperidin-1-yl)butan-1-one
SCHEMBL2110701
CHEMBL2107183
NS00122571
Q27279912