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4'-Fluorocariprazine

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Identification
Molecular formula
C21H25FN2O2
CAS number
877358-00-2
IUPAC name
1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-1-one
State
State

At room temperature, 4'-Fluorocariprazine is typically found in a solid crystalline state. It is generally stable under standard conditions and is not hygroscopic.

Melting point (Celsius)
82.30
Melting point (Kelvin)
355.50
Boiling point (Celsius)
544.60
Boiling point (Kelvin)
817.80
General information
Molecular weight
415.52g/mol
Molar mass
415.5150g/mol
Density
1.2280g/cm3
Appearence

4'-Fluorocariprazine appears as an off-white to light brown crystalline solid. Its physical features may vary slightly depending on the purity level and specific preparation methods utilized in its synthesis.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-1-one

The solubility of 1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-1-one is an important characteristic that influences its application in various chemical and pharmaceutical contexts.

Generally, the solubility of such compounds can be influenced by a variety of factors, including:

  • Molecular Structure: The presence of functional groups, such as the fluorophenyl and methoxyphenyl moieties, can affect polarity and intermolecular interactions, thus impacting solubility.
  • Polarity: Compounds with higher polarity tend to have better solubility in polar solvents such as water, whereas non-polar compounds are often more soluble in organic solvents.
  • Temperature: Increased temperature usually enhances solubility, allowing for more solute to dissolve in a given solvent.
  • pH Level: Changes in the pH of the solvent can alter the ionization of the compound, further impacting solubility.

In practical terms, the solubility of this compound is likely to be relatively moderate due to its complex structure combining both polar and non-polar characteristics. It's critical to perform experimental solubility assessments at varying temperatures and pH levels to obtain precise data.

As noted in many studies, "Understanding solubility is fundamental to the effective application of chemical compounds in real-world scenarios." Therefore, identifying optimal conditions for solubility can pave the way for innovative uses in pharmaceuticals and beyond.

Interesting facts

Interesting Facts about 1-(4-Fluorophenyl)-4-[4-(2-Methoxyphenyl)piperazin-1-yl]butan-1-one

This compound is a fascinating example of the interplay between organic chemistry and pharmacology. As a member of the ketone family, it features both aromatic and aliphatic components that enhance its chemical reactivity and biological activity.

Key Features:

  • Fluorination: The presence of a fluorine atom in the structure significantly influences the compound's properties, such as lipophilicity and metabolic stability. Fluorinated compounds are often more potent and selective in biological applications.
  • Piperazine Derivative: The integration of a piperazine ring offers a unique platform for pharmacological interactions. Piperazines are known for their diverse biological activity, particularly in central nervous system (CNS) drugs.
  • Potential Therapeutic Applications: Due to its structure, this compound may exhibit interesting interactions with serotonin receptors, making it a candidate for mood-modulating therapies.

Moreover, it's worth noting that chemical compounds like this one often undergo rigorous structure-activity relationship (SAR) studies to optimize their efficacy and reduce side effects. The ongoing exploration of derivatives and analogs can lead to discovering new drugs with enhanced properties.

As scientists delve deeper into the optimization of such compounds, they contribute significantly to drug discovery and development, potentially leading to breakthroughs in treating various psychiatric disorders. The future of such compounds is not only promising but also a testament to the intricate dance of chemistry and biology!

Synonyms
Fluanisone
1480-19-9
Fluanison
Haloanison
Haloanisone
Sedalande
Anti-Pica
Metorin
Fluanisona
MD 2028
R 2028
R 2167
Fluanisonum
Fluanisonum [INN-Latin]
NSC 170977
2028 MD
Fluanisona [INN-Spanish]
Fluanisone [INN:BAN:DCF]
EINECS 216-038-8
Fluanisone (INN)
NSC-170977
UNII-1D0W98U1I4
BRN 0707524
Hypnorm (Salt/Mix)
Sedavic (Salt/Mix)
DTXSID4045711
Solusediv (Salt/Mix)
1D0W98U1I4
FLUANISONE [MI]
FLUANISONE [INN]
4'-Fluoro-4-(4-(o-methoxyphenyl)-1-piperazinyl)butyrophenone
4-(4-(o-Methoxyphenyl)-1-piperazinyl)-p-fluorobutyrophenone
FLUANISONE [MART.]
MD-2028
FLUANISONE [WHO-DD]
DTXCID2025711
Butyrophenone, 4'-fluoro-4-[4-(o-methoxyphenyl)-1-piperazinyl]-
R-2028
R-2167
1-Butanone, 1-(4-fluorophenyl)-4-(4-(2-methoxyphenyl)-1-piperazinyl)-
1-Butanone, 1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)-1-piperazinyl]-
5-23-02-00213 (Beilstein Handbook Reference)
haloanizone
4-[4-(o-Methoxyphenyl)-1-piperazinyl]-p-fluorobutyrophenone
4'-Fluoro-4-[4-(o-methoxyphenyl)-1-piperazinyl]butyrophenone
Fluanisonum (INN-Latin)
Fluanisona (INN-Spanish)
BUTYROPHENONE, 4'-FLUORO-4-(4-(o-METHOXYPHENYL)-1-PIPERAZINYL)-
FLUANISONE (MART.)
4'-Fluoro-4-[4(o-methoxyphenyl)-1-piperazinyl]buterophenone
4'-FLUORO-4-)4-(O-METHOXYPHENYL)-1-PIPERAZINYL)BUTYROPHENONE
p-Fluoro-.gamma.-[4-(o-methoxyphenyl)-1-piperazinyl]butyrophenone
1-(4-Fluoro-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-one
4'-Fluoro-4-(4(o-methoxyphenyl)-1-piperazinyl)buterophenone
1-(4-Fluoro-phenyl)-4-(4-(2-methoxy-phenyl)-piperazin-1-yl)-butan-1-one
N05AD09
4'-fluoro-4-(4-(o-methoxyphenyl)-1-piperazinyl)-butyrophenone
p-Fluoro-gamma-(4-(o-methoxyphenyl)-1-piperazinyl)butyrophenone
1-Butanone, 1-(4-fluorophenyl)-4-(4-(2-methoxyphenyl)-1-piperazinyl)-(9CI)
216-038-8
iryfcwpndiuqow-uhfffaoysa-n
1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-1-one
CHEMBL58792
1-(4-fluorophenyl)-4-(4-(2-methoxyphenyl)piperazin-1-yl)butan-1-one
2028 MD; NSC 170977; R 2028
Oprea1_227293
Oprea1_528183
MLS000107485
SCHEMBL145054
REGID_for_CID_15139
CHEBI:177744
HMS2231H24
HMS3373P06
BCP12114
Tox21_110992
BDBM50019959
MFCD00366636
NSC170977
AKOS003669652
DB13665
FF23312
NCGC00077304-01
NCGC00077304-02
SMR000111851
SY267068
TS-09017
WLN: T6N DNTJ A3VR DF& DR BO1
CAS-1480-19-9
DB-229104
HY-117699
CS-0066886
NS00003743
D02621
L000740
SR-01000215056
Q5462605
SR-01000215056-1
1-(4-Fluorophenyl)-4-[4-(2-methoxyphenyl)-1-piperazinyl]-1-butanone #
1-(4-luorophenyl)-4-[4-(2-methoxyphenyl)piperazin-1-yl]butan-1-one
1-Butanone,1-(4-fluorophenyl)-4-[4-(2-methoxyphenyl)-1-piperazinyl]-
1-(4-Fluoro-phenyl)-4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butan-1-one(fluanisone)
4-[4-(o-Methoxyphenyl)-1-piperazinyl]-p-fluorobutyrophenone;Fluanison;4'-Fluoro-4-[4-(o-methoxyphenyl)-1-piperazinyl]butyrophenone