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4'-Fluorococaine

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Identification
Molecular formula
C16H20FNO2
CAS number
84347-77-5
IUPAC name
1-(4-fluorophenyl)-4-(4-hydroxy-1-piperidyl)butan-1-one
State
State

At room temperature, 4'-Fluorococaine is in a solid state.

Melting point (Celsius)
164.50
Melting point (Kelvin)
437.70
Boiling point (Celsius)
357.40
Boiling point (Kelvin)
630.60
General information
Molecular weight
291.35g/mol
Molar mass
291.3530g/mol
Density
1.2330g/cm3
Appearence

4'-Fluorococaine appears as a crystalline powder, often white to off-white in appearance. It is typically odorless and is used in research settings due to its psychoactive properties.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-(4-hydroxy-1-piperidyl)butan-1-one

The solubility of 1-(4-fluorophenyl)-4-(4-hydroxy-1-piperidyl)butan-1-one is an intriguing aspect that can greatly influence its application and behavior in various chemical environments. Several key factors determine its solubility:

  • Polarity: The presence of both a fluorophenyl group and a hydroxy group results in a polar compound, enhancing its ability to dissolve in polar solvents, particularly water.
  • Hydrogen Bonding: The hydroxy group can form hydrogen bonds with water molecules, which typically increases solubility in aqueous solutions.
  • Temperature Sensitivity: Like many organic compounds, its solubility may vary with temperature. Increased temperatures often enhance solubility.
  • pH Dependence: The solubility can also be influenced by the pH of the solution due to ionization of the hydroxy group under different conditions.

In general, compounds with both hydrophilic (like the hydroxy group) and hydrophobic (like the fluorophenyl group) characteristics can manifest unique solubility behaviors. This dual nature may lead to varying solubility in different solvents, which is crucial for its use in pharmaceuticals and chemical synthesis. As an example, in a high-polarity solvent, one could expect better solubility compared to non-polar solvents.

The study of solubility is essential, as it impacts factors such as bioavailability and chemical reactivity. As such, understanding the solubility profile of 1-(4-fluorophenyl)-4-(4-hydroxy-1-piperidyl)butan-1-one can provide significant insights into its practical applications.

Interesting facts

Interesting Facts about 1-(4-fluorophenyl)-4-(4-hydroxy-1-piperidyl)butan-1-one

1-(4-fluorophenyl)-4-(4-hydroxy-1-piperidyl)butan-1-one is a fascinating compound that is notable for its complex structure and potential applications in various fields of science. Below are some intriguing aspects to consider:

  • Pharmacological Potential: This compound is known for its interactions with the central nervous system, which makes it a subject of interest in pharmaceutical research. Its structure may allow it to influence neurotransmitter systems, potentially leading to new treatment options for mental health disorders.
  • Structural Insights: The presence of a fluorine atom in the aromatic ring enhances the compound's lipophilicity. This modification often leads to an increase in the bioactivity of similar compounds.
  • Bonding Dynamics: The unique piperidinyl group contributes to its pharmacokinetic properties, helping researchers understand how structural modifications can affect the behavior of molecules in biological systems.
  • Research Applications: As a synthetic compound, it serves as an essential building block in medicinal chemistry, offering insights into drug design and development practices.
  • Emerging Studies: Ongoing studies are aimed at elucidating the mechanism of action of this compound and its potential side effects, which is crucial for any future therapeutic applications.

In summary, 1-(4-fluorophenyl)-4-(4-hydroxy-1-piperidyl)butan-1-one presents a unique opportunity for scientific exploration. As research progresses, we are likely to uncover more about how its intricate design translates into real-world pharmaceutical applications. The study of such compounds is essential for advancing our understanding of chemistry and its implications in health science.

Synonyms
CHEMBL59213
SCHEMBL20254428
BDBM50019953
AKOS009077567
4-(4-hydroxypiperidino)-4'-fluorobutyrophenone
1-(4-Fluoro-phenyl)-4-(4-hydroxy-piperidin-1-yl)-butan-1-one