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4'-Fluoropropiophenone Methiodide

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Identification
Molecular formula
C14H19ClFNO
CAS number
101-81-5
IUPAC name
1-(4-fluorophenyl)-4-(4-methylpiperidin-1-ium-1-yl)butan-1-one;chloride
State
State

This compound is generally found as a solid at room temperature.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.00
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.00
General information
Molecular weight
259.77g/mol
Molar mass
259.7650g/mol
Density
1.2500g/cm3
Appearence

The compound typically appears as a crystalline solid with varying shades of white to off-white.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-ium-1-yl)butan-1-one; chloride

The solubility of the compound 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-ium-1-yl)butan-1-one; chloride is an intriguing aspect of its chemical behavior, primarily influenced by its ionic nature. In general, the chloride salt form tends to exhibit enhanced solubility in polar solvents. Here are some key points to consider:

  • Water Solubility: The presence of the chloride ion generally suggests that this compound is likely to be water-soluble due to its ionic character. The positive charge on the piperidinium moiety can interact favorably with water molecules.
  • Solvent Polarity: This compound may exhibit varying solubility depending on the polarity of the solvent. Polar solvents (e.g., water, ethanol) will be more effective for solubility than nonpolar solvents (e.g., hexane, toluene).
  • Temperature Dependence: Like many other ionic compounds, solubility can often be enhanced at elevated temperatures. It is essential to consider temperature as a variable when assessing solubility.
  • Complex Formation: Its specific functional groups may allow for complex formation with different solubilizing agents, potentially affecting overall solubility.

As a general guideline, one can state emphatically, "like dissolves like." Therefore, exploring a range of solvents will provide a clearer picture of its solubility characteristics. In summary, this compound is expected to be soluble in polar media while exhibiting limited solubility in nonpolar environments due to its ionic nature and structural attributes.

Interesting facts

Interesting Facts about 1-(4-Fluorophenyl)-4-(4-methylpiperidin-1-ium-1-yl)butan-1-one; chloride

This intriguing compound, often referred to in studies related to medicinal chemistry, showcases a unique structural configuration that opens the door to various scientific explorations. Below are some key points about this compound:

  • Pharmacological Relevance: The presence of the piperidine moiety offers potential in pharmaceutical research, particularly in the development of novel therapeutic agents. Compounds like this one can act as lead structures in drug design.
  • Fluorine Chemistry: The 4-fluorophenyl group is known to enhance the lipophilicity of organic molecules, potentially increasing their bioavailability. This characteristic makes such compounds more favorable in medicinal applications.
  • Ionization Properties: The piperidin-1-ium substitution highlights the significance of ionic forms in biological systems. The ionic character can affect solubility, membrane permeability, and, ultimately, the pharmacological profile of the compound.
  • Analytical Techniques: Techniques such as NMR spectroscopy and mass spectrometry are often employed to study the properties and behavior of compounds like this one, allowing chemists to unveil their structural and electronic attributes.
  • Potential Applications: Beyond pharmaceuticals, this compound may find applications in materials science, specifically in developing functional materials through polymerization reactions involving its active groups.

In the realm of chemistry, compounds like 1-(4-fluorophenyl)-4-(4-methylpiperidin-1-ium-1-yl)butan-1-one; chloride serve as valuable platforms for research and innovation, driving forward our understanding of complex molecular interactions.

Synonyms
Buronil
Eunerpan
1-(4-fluorophenyl)-4-(4-methylpiperidin-1-ium-1-yl)butan-1-one;chloride
1-(3-(p-Fluorobenzoyl)propyl)-4-methylpiperazinium chloride
88G640374K
1-[3-(p-fluorobenzoyl)propyl]-4-methylpiperazinium chloride
SCHEMBL1649537