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PFBT (1-(4-Fluorophenyl)-4-(4-morpholin-4-ium-4-yl-4-propanoyl-piperidin-1-ium-1-yl)butan-1-one dichloride)

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Identification
Molecular formula
C24H36Cl2FN2O3
CAS number
1234567-89-0
IUPAC name
1-(4-fluorophenyl)-4-(4-morpholin-4-ium-4-yl-4-propanoyl-piperidin-1-ium-1-yl)butan-1-one;dichloride
State
State

At room temperature, 1-(4-fluorophenyl)-4-(4-morpholin-4-ium-4-yl-4-propanoyl-piperidin-1-ium-1-yl)butan-1-one dichloride is typically found as a crystalline solid.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.15
General information
Molecular weight
443.36g/mol
Molar mass
443.3620g/mol
Density
1.2156g/cm3
Appearence

1-(4-Fluorophenyl)-4-(4-morpholin-4-ium-4-yl-4-propanoyl-piperidin-1-ium-1-yl)butan-1-one dichloride typically appears as a crystalline solid. The compound may exhibit slightly off-white to white coloration. Its exact hue can be subject to purity and processing conditions.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-(4-morpholin-4-ium-4-yl-4-propanoyl-piperidin-1-ium-1-yl)butan-1-one; dichloride

The solubility of the compound 1-(4-fluorophenyl)-4-(4-morpholin-4-ium-4-yl-4-propanoyl-piperidin-1-ium-1-yl)butan-1-one; dichloride presents intriguing characteristics. Here are some key considerations:

  • Solvent Polarity: Ionic compounds, such as dichlorides, are often more soluble in polar solvents. This means that water, due to its high polarity, may enhance the solubility of this compound significantly.
  • Hydrogen Bonding: The presence of nitrogen and oxygen functional groups suggests potential for hydrogen bonding. This can increase solubility in polar solvents, facilitating the interaction between the solute and solvent molecules.
  • Temperature Effects: Solubility may increase with temperature. This property can be exploited in experimental conditions where higher temperatures might lead to enhanced solubilization.
  • Concentration of Ionization: As a quaternary ammonium compound, its solubility can also be influenced by the concentration of ions in the solution, with higher ionic strength often improving the solubility.

In conclusion, while the solubility of 1-(4-fluorophenyl)-4-(4-morpholin-4-ium-4-yl-4-propanoyl-piperidin-1-ium-1-yl)butan-1-one; dichloride in various solvents warrants thorough testing, one can posulate that its ionic nature and functional groups promote solubility in a range of polar solvents. As always, experimental verification should be undertaken to determine the exact solubility profiles in specific conditions.

Interesting facts

Exploring 1-(4-fluorophenyl)-4-(4-morpholin-4-ium-4-yl-4-propanoyl-piperidin-1-ium-1-yl)butan-1-one;dichloride

This intriguing compound is a fascinating example of complex organic chemistry, particularly because of the structural intricacies involved in its formation. It combines multiple functional groups and demonstrates unique reactivity patterns, making it a subject of interest in medicinal chemistry.

Key Highlights:

  • Pharmacological Potential: The presence of both the morpholine and piperidine moieties suggests that this compound may exhibit various biological activities, which could be explored in drug development.
  • Role of Fluorine: The incorporation of a fluorine atom in the phenyl ring often enhances the lipophilicity and metabolic stability of compounds, which is crucial for therapeutic efficacy.
  • Synthetic Challenges: The synthesis of such a multi-substituted molecule can be quite challenging due to the structural complexity, requiring advanced techniques in organic synthesis.
  • Ionic Nature: As this compound is a dichloride, it likely possesses ionic characteristics that can influence its solubility and reactivity in various solvents.

According to one renowned chemist, "The beauty of chemistry lies in its complexity and simplicity at once." This compound cogently reflects that philosophy as it blends intricate design with the potential for meaningful application.

Further study and characterization could unveil more about its mechanism of action, optimal applications in medicinal chemistry, and potential benefits in treating various conditions. As with many compounds that lie at the intersection of organic and medicinal chemistry, the journey of discovery is often just beginning!

Synonyms
Butyrophenone, 4'-fluoro-4-(4-morpholino-4-propionylpiperidino)-, dihydrochloride
1-(3-(p-Fluorobenzoyl)propyl)-4-(4-morpholino)-4-propionylpiperidine dihydrochloride
1880-04-2