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Fentanyl

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Identification
Molecular formula
C22H28FN3O3
CAS number
437-38-7
IUPAC name
1-(4-fluorophenyl)-4-(4-morpholino-4-propanoyl-1-piperidyl)butan-1-one
State
State

At room temperature, fentanyl is typically a solid, appearing as a white to off-white powder.

Melting point (Celsius)
87.50
Melting point (Kelvin)
360.65
Boiling point (Celsius)
251.50
Boiling point (Kelvin)
524.65
General information
Molecular weight
336.47g/mol
Molar mass
336.4680g/mol
Density
1.3350g/cm3
Appearence

Fentanyl typically appears as a white to off-white powder. It can also be found in a liquid form when prepared as an injectable solution or transdermal patch. As a powder, it is odorless and crystalline.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-(4-morpholino-4-propanoyl-1-piperidyl)butan-1-one

The solubility of the compound 1-(4-fluorophenyl)-4-(4-morpholino-4-propanoyl-1-piperidyl)butan-1-one can be influenced by various factors such as its molecular structure and polarity. Here are some key points regarding its solubility:

  • Polarity: This compound has both polar and non-polar regions, which can affect its solubility in different solvents.
  • Solvent Type: It may demonstrate varied solubility in:
    • Polar solvents: Such as water and alcohols, likely exhibiting some degree of solubility.
    • Non-polar solvents: Such as hydrocarbons, which might result in enhanced solubility due to similar interactions.
  • Temperature: Increasing temperature typically increases solubility for many organic compounds, which may also apply here.
  • pH Dependence: Solubility might change with the pH of the solution, especially if functional groups in the compound can ionize.

In conclusion, while the specific solubility of 1-(4-fluorophenyl)-4-(4-morpholino-4-propanoyl-1-piperidyl)butan-1-one requires experimental determination, its molecular structure suggests a potential for solubility in both polar and non-polar solvents under varying conditions. Understanding these solubility dynamics is crucial for applications in pharmaceuticals and chemical synthesis.

Interesting facts

Interesting Facts About 1-(4-fluorophenyl)-4-(4-morpholino-4-propanoyl-1-piperidyl)butan-1-one

1-(4-fluorophenyl)-4-(4-morpholino-4-propanoyl-1-piperidyl)butan-1-one is a fascinating compound that belongs to a class of synthetic molecules often explored in pharmaceutical research. Here are some notable aspects:

  • Structural Complexity: This compound exhibits a multi-functional structure that combines several pharmacophoric elements. This structural diversity is critical for biological activity and interactions with various biological targets.
  • Role in Drug Discovery: Compounds like this one are often synthesized and analyzed for their potential in drug development. Their unique functional groups, particularly the 4-fluorophenyl and morpholino segments, can enhance receptor binding and selectivity.
  • Potential Applications: While specific therapeutic uses may be under exploration, the presence of the piperidyl and morpholino groups suggests possible activity in treating neurological disorders or conditions related to pain management.
  • Synthetic Pathways: The synthesis of this compound often involves advanced chemical reactions such as amide coupling and fluorination, making it a topic of interest for organic chemists aiming to design efficient synthetic routes.
  • Research Implications: As scientists continue to investigate the structure-activity relationship (SAR) of such compounds, understanding how modifications impact biological efficacy is crucial for the development of new therapeutic agents.

In summary, 1-(4-fluorophenyl)-4-(4-morpholino-4-propanoyl-1-piperidyl)butan-1-one underscores the importance of molecular design in the quest for new medications and serves as a reminder of the vast potential locked within complex organics.

Synonyms
NSC665323
CHEMBL2009473
NCI60_022533
1-(4-fluorophenyl)-4-(4-morpholino-4-propanoyl-1-piperidyl)butan-1-one
1-(4-Fluorophenyl)-4-(4-(4-morpholinyl)-4-propionyl-1-piperidinyl)-1-butanone hydrochloride