Skip to main content

Fluorophenylpiprazinone

ADVERTISEMENT
Identification
Molecular formula
C20H23FN2O
CAS number
211915-06-9
IUPAC name
1-(4-fluorophenyl)-4-(4-phenylpiperazin-1-yl)butan-1-one
State
State

At room temperature, the compound is typically in a solid state. It is stable under standard conditions and should be handled with care, avoiding exposure to moisture or high temperatures. Proper storage in a cool, dry place is recommended to maintain its integrity and prevent degradation.

Melting point (Celsius)
89.00
Melting point (Kelvin)
362.15
Boiling point (Celsius)
459.50
Boiling point (Kelvin)
732.50
General information
Molecular weight
344.44g/mol
Molar mass
344.4390g/mol
Density
1.2100g/cm3
Appearence

The compound 1-(4-Fluorophenyl)-4-(4-phenylpiperazin-1-yl)butan-1-one typically appears as a crystalline solid. It may vary in color from white to off-white or slightly yellow, depending on its degree of purity and any impurities present. The solid form can appear as fine crystals or a crystalline powder.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-(4-phenylpiperazin-1-yl)butan-1-one

The solubility of 1-(4-fluorophenyl)-4-(4-phenylpiperazin-1-yl)butan-1-one can be influenced by various factors including temperature, pH, and the presence of solvents. This compound, characterized by its complex structure, may exhibit distinct solubility properties in different solvents.

  • Polar solvents: Compounds with nitrogen atoms, like this one, may have increased solubility in polar solvents such as water and alcohols due to potential hydrogen bonding.
  • Non-polar solvents: Conversely, the phenyl groups suggest better solubility in non-polar organic solvents like chloroform, benzene, or ether.
  • Temperature effects: As the temperature increases, solubility is often enhanced, making it crucial in practical applications like formulation and synthesis.

Experimental studies are vital to determine the exact solubility parameters, as the intricate balance between polar and non-polar characteristics can lead to unique interactions within various media.

Understanding the solubility of this compound can significantly aid in predicting its behavior in biological systems and its suitability for medicinal formulation.

Interesting facts

Interesting Facts about 1-(4-Fluorophenyl)-4-(4-phenylpiperazin-1-yl)butan-1-one

1-(4-Fluorophenyl)-4-(4-phenylpiperazin-1-yl)butan-1-one is a fascinating compound that represents the intersection of medicinal chemistry and pharmacology. Below are some intriguing highlights:

  • Pharmacological Potential: This compound belongs to a class of chemicals that have shown promise in various therapeutic areas, particularly in treating conditions like depression and anxiety. Its structure suggests that it may interact with several key neurotransmitter systems in the brain.
  • Structural Complexity: The compound's unique architecture, featuring a butanone moiety and a piperazine ring, contributes to its potential specificity for certain biological targets. Such structural motifs are often paramount in enhancing the pharmacokinetic properties of drug candidates.
  • Fluoro-substitution: The presence of a fluorine atom in the aromatic ring can significantly influence the compound's lipophilicity and metabolic stability, allowing it to traverse the blood-brain barrier more effectively and possibly increase its activity.
  • Pharmacophore Considerations: This compound can be considered as a potential pharmacophore, which refers to the part of the molecule responsible for its biological activity. Studying its interactions can offer insights into new drug development strategies.
  • Research Applications: The compound is often employed in various research scenarios, including studies investigating receptor binding, enzyme inhibition, and even in the development of new methodologies for synthesizing complex organic molecules.
  • Potential Side Effects: As with many compounds interacting with neurotransmitter systems, it is critical to evaluate the safety profile and side effects thoroughly. Understanding these aspects can aid in designing better therapeutic agents with fewer adverse effects.

In summary, 1-(4-Fluorophenyl)-4-(4-phenylpiperazin-1-yl)butan-1-one represents much more than just a chemical formula; it embodies the spirit of innovation in the pharmaceutical sciences. As research continues to unfold, the compound may reveal even more about the intricate workings of human biochemistry.

Synonyms
Butropipazone
Butropipazon
Galvanisone
Butyropipazone
2354-61-2
1-Butanone, 1-(4-fluorophenyl)-4-(4-phenyl-1-piperazinyl)-
R 1892
NSC 170975
BUTYROPHENONE, 4'-FLUORO-4-(4-PHENYL-1-PIPERAZINYL)-
4'-Fluoro-4-(1-(4-phenyl)piperazino)butyrophenone
BRN 0895232
gamma-(4-Phenylpiperazino)-4-fluorobutyrophenone
DTXSID50178122
5-23-02-00209 (Beilstein Handbook Reference)
.gamma.-(4-Phenylpiperazino)-4-fluorobutyrophenone
4'-Fluoro-4-[1-(4-phenyl)piperazino]butyrophenone
DTXCID80100613
1-Butanone, 1-(4-fluorophenyl)-4-(4-phenyl-1-piperazinyl)-(9CI)
qphrvumzluqzgu-uhfffaoysa-n
1-(4-fluorophenyl)-4-(4-phenylpiperazin-1-yl)butan-1-one
47UB2NB3UD
MLS003106750
NSC-170975
UNII-47UB2NB3UD
Oprea1_538932
SCHEMBL6234537
CHEMBL2362425
WLN: T6NTJ A1OR DF& DR
NSC170975
STK544074
AKOS005473486
FF94678
SMR001821639
Z137558384
1-(4-Fluorophenyl)-4-(4-phenyl-1-piperazinyl)-1-butanone
1-(4-Fluorophenyl)-4-(4-phenyl-1-piperazinyl)-1-butanone #
1-(4-Fluorophenyl)-4-(4-phenylpiperazin-1-Yl)butan-1-one hydrochloride