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Varenicline Tartrate

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Identification
Molecular formula
C18H20FION
CAS number
162638-49-8
IUPAC name
1-(4-fluorophenyl)-4-(8-methyl-8-azoniaspiro[4.5]decan-8-yl)butan-1-one;iodide
State
State

At room temperature, the compound is in a solid state, appearing as a powder.

Melting point (Celsius)
220.00
Melting point (Kelvin)
493.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
475.41g/mol
Molar mass
475.4060g/mol
Density
1.4050g/cm3
Appearence

The compound typically appears as a white to off-white powder.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-(8-methyl-8-azoniaspiro[4.5]decan-8-yl)butan-1-one; iodide

The solubility of 1-(4-fluorophenyl)-4-(8-methyl-8-azoniaspiro[4.5]decan-8-yl)butan-1-one; iodide is influenced by several factors due to its complex structure. This compound contains a quaternary ammonium ion, which typically increases solubility in polar solvents, such as:

  • Water: The ionizable nature of the compound may enhance its solubility in aqueous solutions.
  • Alcohols: The presence of hydroxyl groups can form hydrogen bonds with the ionic part of the compound, aiding solubility.
  • Aromatic solvents: Although less favorable, some degree of solubility might still occur due to the presence of the fluoro-substituted aromatic ring.

However, it is essential to note that the solubility can vary significantly depending on temperature and the specific solvent system employed. For instance:

  • Higher temperatures often increase solubility by providing more kinetic energy to the molecules.
  • Different solvents can interact variably with the compound, so empirical testing is often necessary.

In conclusion, while this compound is expected to exhibit reasonable solubility in polar solvents due to its cationic characteristics, specific solubility testing is crucial to understand its behavior in various matrices, ensuring comprehensive knowledge for practical applications.

Interesting facts

Interesting Facts about 1-(4-fluorophenyl)-4-(8-methyl-8-azoniaspiro[4.5]decan-8-yl)butan-1-one; iodide

This intriguing compound showcases the fascinating intersection of organic chemistry and medicinal research. Recognized for its unique structure and functional groups, it embodies several significant properties and potential applications:

  • Pharmacological Potential: Compounds like this one, featuring fluorinated aromatic rings and azonia frameworks, are frequently explored in the pharmaceutical industry for their biological activity. The fluorine atom enhances metabolic stability, making it a key player in drug design.
  • Structural Diversity: The spirocyclic structure contributes to the compound's rigidity and selectivity. This aspect is vital in the development of drugs that require precise interactions with biological targets.
  • Charge Characteristics: The presence of the iodide ion signifies a charged species, which can influence how the compound interacts with cellular membranes and biological systems. Ionic compounds often show varying solubility and permeability, impacting their pharmacokinetics.
  • Research Applications: This compound is of particular interest in materials science and organic synthesis. Its unique characteristics allow it to function as an intermediate for synthesizing other complex molecules.

"In chemistry, the structures we create can lead to wonders that go beyond conventional limits." This thought resonates with the ongoing research surrounding compounds like 1-(4-fluorophenyl)-4-(8-methyl-8-azoniaspiro[4.5]decan-8-yl)butan-1-one; iodide, as scientists delve into its potential applications in drug discovery and beyond.

Exploring compounds that have unique structural features and properties not only enriches our understanding of chemical behavior but also sparks innovation across various scientific fields.

Synonyms
1096-06-6
8-(3-(p-Fluorobenzoyl)propyl)-8-methyl-8-azoniaspiro(4.5)decane iodide
8-AZONIASPIRO(4.5)DECANE, 8-(3-(p-FLUOROBENZOYL)PROPYL)-8-METHYL-, IODIDE
DTXSID50911253
8-[4-(4-Fluorophenyl)-4-oxobutyl]-8-methyl-8-azaspiro[4.5]decan-8-ium iodide