Spirolactam | Solubility of Things

Identification

Molecular formula

C₂₂H₂₈FN₂O

CAS number

1270003-06-1

IUPAC name

1-(4-fluorophenyl)-4-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)butan-1-one

State

At room temperature, it exists as a solid. This compound is known for its stability in various conditions, making it an ideal candidate for chemical synthesis and pharmacological studies.

Melting point (Celsius)

172.00

Melting point (Kelvin)

445.15

Boiling point (Celsius)

337.00

Boiling point (Kelvin)

610.15

General information

Molecular weight

362.48g/mol

Molar mass

362.4980g/mol

Density

1.1790g/cm³

Appearence

This compound is typically a solid crystalline substance. The appearance can range from off-white to light brown powder depending on the purity and specific synthetic methods used.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)butan-1-one

The solubility of 1-(4-fluorophenyl)-4-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)butan-1-one is a topic of interest due to its unique structural features. Understanding the solubility properties of this compound is crucial because they can dictate its applicability in various chemical processes. Here are some key points regarding the solubility:

Polar vs. Non-Polar Nature: This compound contains both polar and non-polar functional groups, which may lead to amphiphilic characteristics. The presence of the fluorophenyl group tends to enhance polarity, potentially affecting solubility in polar solvents.
Solvent Compatibility: The solubility is likely influenced by the choice of solvent. It may dissolve readily in:

Polar solvents (e.g., water, methanol) due to hydrogen bonding with polar functional groups.
Non-polar solvents (e.g., hexane, toluene) because of the hydrophobic interactions with non-polar regions.

Temperature Effects: Temperature variations can significantly impact solubility. Generally, increased temperature may enhance solubility, especially for solid compounds.
Concentration Limits: At high concentrations, solubility may be limited due to potential aggregative phenomena or solute-solute interactions.

As such, the solubility of this compound is not just a single characteristic but depends on a multitude of factors including the solvent type, temperature, and concentration levels. Understanding these nuances can greatly aid in the effective application and utilization of this intriguing compound in chemical research and industry.

Interesting facts

Interesting Facts about 1-(4-fluorophenyl)-4-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)butan-1-one

This compound, a member of the class of spirocyclic compounds, has garnered attention due to its unique structural characteristics and potential biological activities. Here are some intriguing points regarding it:

Spirocyclic Structure: The presence of the spirocyclic moiety in this compound introduces a level of strain and configurational rigidity that can have significant implications in medicinal chemistry.
Fluorine Atoms: The incorporation of a fluorophenyl group is interesting because fluorine is known to enhance the lipophilicity and metabolic stability of organic compounds.
Potential Applications: Compounds like this have been investigated for their roles in drug design, particularly as potential therapeutics targeting various biological pathways.
Biological Activity: Research indicates that similar compounds may exhibit neuroactive properties, making them candidates for the treatment of neurological disorders.

As one delves deeper into the realm of organic and medicinal chemistry, compounds such as 1-(4-fluorophenyl)-4-(9-methyl-3,9-diazaspiro[5.5]undecan-3-yl)butan-1-one open up avenues for innovative drug discovery. The intricate interplay of its functional groups and structural elements may yield valuable insights into new therapeutic strategies.

In summary, this compound not only showcases the beauty of chemical diversity but also holds potential for groundbreaking developments in pharmaceuticals.