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4-Fluoro-alpha-PVP hydrochloride

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Identification
Molecular formula
C15H20ClFNO
CAS number
1373918-61-6
IUPAC name
1-(4-fluorophenyl)-4-piperidin-1-ium-1-yl-butan-1-one;chloride
State
State

At room temperature, this compound is typically a solid.

Melting point (Celsius)
156.00
Melting point (Kelvin)
429.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
285.78g/mol
Molar mass
285.1780g/mol
Density
1.2000g/cm3
Appearence

This compound is generally a white, crystalline powder. It may appear slightly off-white depending on purity and handling conditions.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-4-piperidin-1-ium-1-yl-butan-1-one;chloride

The solubility of 1-(4-fluorophenyl)-4-piperidin-1-ium-1-yl-butan-1-one;chloride in water and organic solvents is of significant interest due to its piperidine moiety and ionic nature. Generally, quaternary ammonium salts like this compound tend to exhibit high solubility in polar solvents such as water, owing to the ionic charge which enhances electrostatic interactions with the water molecules.

Key points regarding the solubility of this compound include:

  • Ionic Nature: The presence of the chloride ion makes this compound readily soluble in water due to strong ion-dipole interactions.
  • Solvent Polarity: Enhanced solubility is expected in polar solvents compared to nonpolar solvents. For instance, it may have low solubility in hydrocarbons.
  • Temperature Dependence: The solubility may increase with temperature; thus, higher temperatures may facilitate better dissolution.

To summarize, one can expect this compound to be soluble in water and other polar solvents, while showing limited solubility in nonpolar media. Its unique structure and ionic properties play a crucial role in its solubility characteristics, making it an intriguing compound for further study.

Interesting facts

Interesting Facts about 1-(4-fluorophenyl)-4-piperidin-1-ium-1-yl-butan-1-one;chloride

This compound is a member of the piperidine alkaloids family, notable for its unique structural features and potential applications in the pharmaceutical and agrochemical sectors. Its molecular architecture includes a piperidine ring, which is a six-membered ring containing one nitrogen atom. Here are some intriguing aspects of this compound:

  • Synthetic Pathways: The synthesis of this compound can be accomplished through various methods, often involving the manipulation of piperidine derivatives and functional groups. This opens avenues for tailored applications.
  • Pharmacological Potential: Compounds containing piperidine moieties are often investigated for their bioactive properties. They may exhibit activity as antidepressants, antipsychotics, or analgesics. Research into their therapeutic potential continues to expand our understanding of their mechanisms.
  • Fluoro-substitution Effects: The presence of the fluorine atom in this compound enhances its lipophilicity and metabolic stability. This modification can impact the pharmacokinetics and pharmacodynamics of the compound, making it a subject of interest in medicinal chemistry.
  • Research Applications: Chemical compounds similar to this one are often utilized as reference standards in analytical chemistry, aiding in the development of new drugs and understanding biochemical pathways.

Furthermore, the chloride component of this compound indicates its ionic nature, which can play a significant role in its solubility and reactivity. As emphasized by numerous studies, the interplay between different substituents in organic compounds can lead to fascinating variations in behavior and efficacy, illuminating the path for new discoveries in chemical research.

In summary, 1-(4-fluorophenyl)-4-piperidin-1-ium-1-yl-butan-1-one;chloride exemplifies the complexity and potential of synthetic organic compounds, making it an exciting subject for both research and applications in various fields.

Synonyms
1219-36-9
1-[3-(P-FLUOROBENZOYL)PROPYL]PIPERIDINIUM CHLORIDE
1-(4-fluorophenyl)-4-piperidin-1-ium-1-ylbutan-1-one;chloride
1-(3-(p-Fluorobenzoyl)propyl)piperidinium chloride
EINECS 214-942-7
4'-Fluoro-4-piperidinobutyrophenone hydrochloride
1-(3-(p-Fluorobenzoyl)propyl)piperidine hydrochloride
BUTYROPHENONE, 4'-FLUORO-4-PIPERIDINO-, HYDROCHLORIDE
NS00044146