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Pipofezine

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Identification
Molecular formula
C27H39FN2O2
CAS number
138962-77-3
IUPAC name
1-(4-fluorophenyl)-9-[4-(2-methoxyphenyl)piperazin-1-yl]nonan-1-one
State
State
Pipofezine is typically found as a solid at room temperature.
Melting point (Celsius)
127.00
Melting point (Kelvin)
400.15
Boiling point (Celsius)
543.70
Boiling point (Kelvin)
816.85
General information
Molecular weight
440.61g/mol
Molar mass
440.5790g/mol
Density
1.1422g/cm3
Appearence

Pipofezine typically appears as a crystalline powder.

Comment on solubility

Solubility of 1-(4-fluorophenyl)-9-[4-(2-methoxyphenyl)piperazin-1-yl]nonan-1-one

The solubility of 1-(4-fluorophenyl)-9-[4-(2-methoxyphenyl)piperazin-1-yl]nonan-1-one is a crucial factor in determining its bioavailability and overall efficacy in various applications. This compound, characterized by its complex structure, exhibits varying solubility properties influenced by several factors:

  • Polarity: The presence of polar and nonpolar functional groups affects the compound's interaction with solvents. For instance, the fluorophenyl and methoxyphenyl groups may enhance solubility in organic solvents.
  • Temperature: As with many chemical compounds, solubility can increase with temperature, altering the way this compound behaves in solution.
  • pH Levels: The solubility might also vary significantly with different pH levels due to protonation or deprotonation of active sites within the molecule.

Experiments and studies frequently show that:

  • Increasing temperature can lead to greater solubilization of the compound in organic solvents.
  • Altering the pH may enhance or reduce solubility, a critical consideration in drug formulation.

In summary, the solubility of 1-(4-fluorophenyl)-9-[4-(2-methoxyphenyl)piperazin-1-yl]nonan-1-one is impacted by its molecular structure, temperature, and pH, necessitating tailored approaches in its utilization. Understanding these solubility characteristics is essential for optimizing its application in pharmaceuticals and other fields.

Interesting facts

Interesting Facts about 1-(4-fluorophenyl)-9-[4-(2-methoxyphenyl)piperazin-1-yl]nonan-1-one

This compound, known for its intricate structure, is often categorized within the realm of pharmaceuticals and organic synthesis. Here are some engaging insights regarding this fascinating molecule:

  • Pharmacological Properties: The compound is of significant interest in medicinal chemistry due to its potential interactions with neurotransmitter systems. Compounds of this nature can often act as ligands for various receptors in the brain, which plays a crucial role in developing treatments for psychiatric disorders.
  • Structural Complexity: The presence of a piperazine ring and multiple aromatic groups indicates a compound designed for specific interactions. This highlights the intricate nature of drug design, where every atom is strategically placed to enhance efficacy and reduce side effects.
  • Fluorine Impact: The incorporation of a fluorine atom is particularly noteworthy. Fluorine can significantly modify a compound's lipophilicity and metabolic stability, which can ultimately affect its pharmacokinetics and pharmacodynamics.
  • Potential Applications: Research has shown that compounds similar to this one may aid in treating conditions like anxiety and depression. Their ability to modulate serotonin and dopamine levels could lead to breakthroughs in mental health treatments.
  • Research Interest: Ongoing studies in the field of medicinal chemistry are delving into the potential of fluorinated compounds, as they may exhibit unique therapeutic benefits that are not present in their non-fluorinated analogs.

In conclusion, the compound 1-(4-fluorophenyl)-9-[4-(2-methoxyphenyl)piperazin-1-yl]nonan-1-one showcases the marvel of chemical synthesis and its applications in drug discovery. As researchers continue to explore its properties, this compound could serve as a key player in developing new therapeutic agents.

Synonyms
BRN 0720034
NONANOPHENONE, 4'-FLUORO-9-(4-(o-METHOXYPHENYL)-1-PIPERAZINYL)-
17160-21-3
4'-Fluoro-9-(4-(o-methoxyphenyl)-1-piperazinyl)nonanophenone
DTXSID10169137
DTXCID7091628