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4-Fluoroamphetamine

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Identification
Molecular formula
C9H12FN
CAS number
459-02-9
IUPAC name
1-(4-fluorophenyl)propan-2-amine
State
State

4-Fluoroamphetamine is typically a solid at room temperature, commonly found in the form of crystalline powder. It is relatively stable in air under normal conditions but should be stored in a cool, dry place, protected from light to preserve its integrity.

Melting point (Celsius)
126.00
Melting point (Kelvin)
399.00
Boiling point (Celsius)
174.00
Boiling point (Kelvin)
447.00
General information
Molecular weight
153.20g/mol
Molar mass
153.2070g/mol
Density
0.9000g/cm3
Appearence

4-Fluoroamphetamine is typically encountered as a crystalline solid or powder. Its color can range from white to off-white or slightly pinkish, depending on the method of preparation and the presence of impurities. The compound is usually odorless.

Comment on solubility

Solubility of 1-(4-fluorophenyl)propan-2-amine

The solubility of 1-(4-fluorophenyl)propan-2-amine, a compound notable for its unique structure, can be influenced by several factors.

Key Solubility Considerations:

  • Polarity: The presence of both the aromatic fluorophenyl group and the aliphatic amine influences its overall polarity, impacting solubility in various solvents.
  • Hydrogen Bonding: The amine functional group can participate in hydrogen bonds, enhancing solubility in polar solvents such as water.
  • Temperature Effects: Increased temperature typically leads to higher solubility due to enhanced molecular motion.

In general, 1-(4-fluorophenyl)propan-2-amine is expected to exhibit moderate solubility in water and higher solubility in organic solvents like ethanol or methanol, making it versatile for various applications.

It's essential to remember that the solubility can also be affected by environmental factors such as pH and ionic strength. Therefore, understanding these factors is crucial for predicting the behavior of 1-(4-fluorophenyl)propan-2-amine in different solutions.

Interesting facts

Interesting Facts about 1-(4-fluorophenyl)propan-2-amine

1-(4-fluorophenyl)propan-2-amine, commonly known as fluoroamphetamine, is a fascinating compound that has garnered attention in both scientific and public spheres. Here are some key points to consider:

  • Classification: This compound belongs to the family of amphetamines, a class known for their stimulant effects.
  • Structure: The presence of a fluorine atom in the para position of the phenyl ring is noteworthy. This substitution can significantly modify its pharmacological properties compared to its parent compound, amphetamine.
  • Applications: Fluoroamphetamines have been explored for their potential therapeutic uses, especially in treating attention disorders and mood-related conditions. Their unique structural modifications may enhance activity within the nervous system.
  • Research Insights: Studies indicate that compounds like fluoroamphetamines can act as potent catecholamine reuptake inhibitors, influencing neurotransmitter levels such as dopamine and norepinephrine in the brain.
  • Public Awareness: The compound has also been highlighted in discussions regarding novel psychoactive substances. Its legality can vary between countries, making it a topic of interest in drug policy and public health debates.

In summary, 1-(4-fluorophenyl)propan-2-amine is an intriguing compound that exemplifies the complexity and dual nature of amphetamines—ranging from potential medical benefits to concerns over misuse. As research advances, understanding the full scope of its effects and applications will remain a vibrant area of study.

Synonyms
4-Fluoroamphetamine
459-02-9
p-Fluoroamphetamine
1-(4-Fluorophenyl)propane-2-amine
1-(4-fluorophenyl)propan-2-amine
(+-)-p-Fluoroamphetamine
4-FA
fluoroamphetamine
2-(4-Fluoro-phenyl)-1-methyl-ethylamine
p-Fluoro-alpha-methylphenethylamine
4-Fluoro-alpha-methylphenethylamine
UNII-S5744XYR1Z
S5744XYR1Z
p-Fluoro-.alpha.-methylphenethylamine
4-FMP
Benzeneethanamine, p-fluoro-alpha-methyl-
Phenethylamine, p-fluoro-.alpha.-methyl-
PHENETHYLAMINE, p-FLUORO-alpha-METHYL-
Benzeneethanamine, 4-fluoro-.alpha.-methyl-
PAL-303
(+/-)-P-FLUOROAMPHETAMINE
4-Fluoro-.alpha.-methylphenethylamine
J50.057G
1-(4-FLUOROPHENYL)-2-PROPANEAMINE
(RS)-1-(4-FLUOROPHENYL)PROPAN-2-AMINE
788123-23-9
72522-20-4
para-fluoroamphetamine
Benzeneethanamine, 4-fluoro-alpha-methyl-
1-(4-FLUOROPHENYL)-2-PROPYLAMINE
NCIOpen2_001428
SCHEMBL712487
CHEMBL2009392
DTXSID90894758
MFCD20449118
1-(4-Fluorophenyl)-2-propanamine #
AKOS000148841
AKOS022196416
AB76425
AB76433
(R)-1-(4-Fluorophenyl)-2-propanamine
(S)-1-(4-Fluorophenyl)-2-propanamine
AC-26261
NCI60_042091
PD048378
SY383256
SY383257
DB-070693
NS00006567
C22767
Q229962
(+/-)-2-(4-fluoro-phenyl)-1-methyl-ethyl-amine
(1R)-2-(4-FLUOROPHENYL)-1-METHYLETHYLAMINE
(1S)-2-(4-FLUOROPHENYL)-1-METHYLETHYLAMINE