Skip to main content

Arbutin

ADVERTISEMENT
Identification
Molecular formula
C12H16O7
CAS number
497-76-7
IUPAC name
1-(4-hydroxy-3-methoxy-phenyl)ethane-1,2-diol
State
State
At room temperature, arbutin is a solid. It is typically utilized in powdered form, especially in pharmaceutical and cosmetic industries.
Melting point (Celsius)
199.00
Melting point (Kelvin)
472.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
272.25g/mol
Molar mass
272.2510g/mol
Density
1.5500g/cm3
Appearence
Arbutin, a glycosylated hydroquinone, appears as a white crystalline powder. It is often used in cosmetic formulations for skin lightening and treating hyperpigmentation. The compound’s appearance is crucial for its identification and use in various applications.
Comment on solubility

Solubility of 1-(4-hydroxy-3-methoxy-phenyl)ethane-1,2-diol

1-(4-hydroxy-3-methoxy-phenyl)ethane-1,2-diol, often referred to as a phenolic compound due to its structure, exhibits some intriguing solubility characteristics.

  • Polar Nature: The presence of hydroxyl groups (-OH) in its structure contributes to its polar nature, enhancing its solubility in polar solvents.
  • Solubility in Water: This compound is generally soluble in water, which can be attributed to hydrogen bonding capabilities with water molecules.
  • Solvent Variability: It is also soluble in various organic solvents such as ethanol and methanol, but less soluble in non-polar solvents like hexane.
  • Concentration Factors: The exact degree of solubility may vary significantly with changes in temperature and concentration.
  • Practical Applications: Understanding the solubility is crucial for its application in pharmaceuticals and cosmetics, where its solubility profile can affect bioavailability and formulation stability.

In summary, the solubility of 1-(4-hydroxy-3-methoxy-phenyl)ethane-1,2-diol is a vital aspect to consider, given its implications in both laboratory settings and practical applications. As the saying goes, *“Like dissolves like,”* emphasizing the importance of solvent choice in exploring the solubility of this compound.

Interesting facts

Interesting Facts about 1-(4-hydroxy-3-methoxy-phenyl)ethane-1,2-diol

1-(4-hydroxy-3-methoxy-phenyl)ethane-1,2-diol, commonly known as Tyrosol, is an intriguing compound found in numerous plants and natural sources. Here are some noteworthy aspects:

  • Nutritional Benefits: Tyrosol is known for its antioxidant properties, contributing to its potential health benefits, such as improving cardiovascular health and reducing inflammation.
  • Natural Sources: This compound is abundantly found in olives, olive oil, and various fruits. Its presence in these foods is one of the reasons they are often touted for their health benefits.
  • Metabolic Pathways: Tyrosol plays a role in the synthesis of various neurotransmitters, particularly dopamine. It is formed from the amino acid tyrosine, highlighting the interconnectedness of amino acids and phenolic compounds in metabolic pathways.
  • Research Spotlight: Studies have indicated that Tyrosol may possess neuroprotective effects. Research is ongoing to explore its potential therapeutic applications in neurodegenerative diseases.
  • Flavor and Aroma: Tyrosol contributes to the flavor profile of certain wines and can impart a subtle sweetness and aromatic complexity, making it an interesting compound for the food and beverage industry.

In summary, 1-(4-hydroxy-3-methoxy-phenyl)ethane-1,2-diol is more than just a chemical compound; it serves as a bridge between nutrition, health, and sensory experiences. Its unique properties and beneficial effects continue to be subjects of research and exploration.

Synonyms
Vanylglycol
534-82-7
3-Methoxy-4-hydroxyphenylglycol
METHOXYHYDROXYPHENYLGLYCOL
Vanilethanediol
4-Hydroxy-3-methoxyphenyl glycol
4-Hydroxy-3-methoxyphenylglycol
98LK01183Z
3-METHOXY-4-HYDROXYPHENYLGLYCOL [MI]
4 Hydroxy 3 methoxyphenylethylene Glycol
methoxy-hydroxyphenyl glycol
4 Hydroxy 3 methoxyphenylglycol
4 Hydroxy 3 methoxyphenylethyleneglycol
4-Hydroxy-3-methoxyphenylethyleneglycol
4-Hydroxy-3-methoxyphenylethylene Glycol
3-methoxy-4-hydroxyphenylglycol, (+-)-
fbwpwwwzwkpjfl-uhfffaoysa-n
mhpg piperazine
MHPG
MOPEG
1-(4-hydroxy-3-methoxyphenyl)ethane-1,2-diol
4-HYDROXY-3-METHOXY-D3-PHENYLETHYLENE GLYCOL
HMPG
Hydroxymethoxyphenylglycol
rac 4-Hydroxy-3-methoxyphenylethylene Glycol
1-(4-Hydroxy-3-methoxyphenyl)-1,2-ethanediol
CHEBI:1576
3-Methoxy-4-hydroxyphenyl glycol
1,2-Ethanediol, 1-(4-hydroxy-3-methoxyphenyl)-
3-Methoxy-4-hydroxyphenylethyleneglycol
3-METHOXY-4-HYDROXYPHENYLGLYCOL, (+/-)-
(4-Hydroxy-3-methoxyphenyl)ethylene glycol
UNII-98LK01183Z
SCHEMBL43536
CHEMBL1322392
DTXSID20862142
4-Hydroxy-3-methoxy-b-phenylglycol
4-Hydroxy-3-methoxy-beta-phenylglycol
FH27459
SDCCGSBI-0633731.P001
3-methoxy-4-hydroxyphenylethylene glycol
NCGC00015498-02
NCGC00015498-03
NCGC00015498-05
NCGC00162188-01
HY-113323
CS-0059602
NS00074330
rac-4-Hydroxy-3-methoxyphenylethylene glycol
C05594
G77018
EN300-1830443
1-(4-Hydroxy-3-methoxyphenyl)-1,2-ethanediol #
Q223097
SR-01000075158
SR-01000075158-1