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Vanillin acetate

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Identification
Molecular formula
C9H10O3
CAS number
121-33-5
IUPAC name
1-(4-hydroxy-3-methoxy-phenyl)propan-1-one
State
State

At room temperature, 1-(4-hydroxy-3-methoxy-phenyl)propan-1-one is in a solid state, presenting as a crystalline powder.

Melting point (Celsius)
81.00
Melting point (Kelvin)
354.15
Boiling point (Celsius)
372.00
Boiling point (Kelvin)
645.15
General information
Molecular weight
152.15g/mol
Molar mass
152.1490g/mol
Density
1.0880g/cm3
Appearence

1-(4-Hydroxy-3-methoxy-phenyl)propan-1-one appears as a brown crystalline powder. It has a distinct and pleasant vanilla aroma, which is characteristic of compounds related to vanillin.

Comment on solubility

Solubility of 1-(4-hydroxy-3-methoxy-phenyl)propan-1-one

The solubility of 1-(4-hydroxy-3-methoxy-phenyl)propan-1-one, also known as 4-hydroxy-3-methoxyacetophenone, is influenced by several factors due to its specific functional groups. Its structure comprises both hydrophilic and hydrophobic segments, which dictates its solubility behavior in various solvents.

Factors Influencing Solubility:

  • Polarity: The presence of hydroxy (-OH) and methoxy (-OCH3) groups enhances its solubility in polar solvents like water.
  • Solvent Type: It displays better solubility in organic solvents such as ethanol, methanol, and acetone, where its aromatic nature can participate in hydrogen bonding.
  • Temperature: As with many organic compounds, increasing the temperature can improve dissolution rates, making it more soluble.

In practical scenarios, it is noted that:

  • At room temperature, the solubility in water is moderate.
  • Enhanced solubility can be achieved by utilizing co-solvents in formulations.

Overall, the solubility characteristics of 1-(4-hydroxy-3-methoxy-phenyl)propan-1-one are vital for its application in various fields, including pharmaceuticals, where solubility plays a crucial role in bioavailability.

Interesting facts

Explore the Fascinating World of 1-(4-hydroxy-3-methoxy-phenyl)propan-1-one

1-(4-hydroxy-3-methoxy-phenyl)propan-1-one, often referred to as a derivative of an important natural compound, showcases the intricate relationship between structure and function in organic chemistry. Here are some fascinating insights about this compound:

  • Natural Origins: This compound is explicitly related to the renowned flavonoid family, which is known for their diverse roles in plants and their beneficial effects on human health.
  • Biological Activities: Compounds like this one are frequently studied for their antioxidant, anti-inflammatory, and antimicrobial properties. Research suggests they can assist in reducing oxidative stress in cells.
  • Chemical Versatility: 1-(4-hydroxy-3-methoxy-phenyl)propan-1-one can act as a precursor in synthesizing more complex organic compounds, making it valuable in organic synthesis.
  • Potential Therapeutic Applications: There is ongoing research exploring the use of this compound in developing therapeutic agents for various diseases, including cancer and cardiovascular ailments.
  • Preparation Techniques: This compound can be synthesized through various chemical reactions, including condensation and oxidation processes, making it a popular topic in organic chemistry labs.

The exploration of 1-(4-hydroxy-3-methoxy-phenyl)propan-1-one offers significant insights into medicinal chemistry, the development of natural products, and the fascinating interplay of molecular structure with biological activity. As research continues within this field, the potential applications of such compounds could pave the way for innovative treatments and solutions.

In conclusion: The journey of understanding compounds like 1-(4-hydroxy-3-methoxy-phenyl)propan-1-one is not just a pursuit of scientific curiosity; it is a step towards unlocking the mysteries of nature.

Synonyms
1835-14-9
Propiovanillone
4-Hydroxy-3-methoxypropiophenone
Propioguaiacol
NSC 16691
1-(4-hydroxy-3-methoxyphenyl)propan-1-one
3-Methoxy-4-hydroxypropiophenone
Propioguaiacone
1-Propanone, 1-(4-hydroxy-3-methoxyphenyl)-
1-(4-hydroxy-3-methoxyphenyl)-1-propanone
B6B3PL2HRF
NSC-16691
SMR000386916
1-propiovanillone
1-(4-Hydroxy-3-methoxy-phenyl)-propan-1-one
MFCD00482070
Propiophenone, 4'-hydroxy-3'-methoxy
UNII-B6B3PL2HRF
1-(4-hydroxy-3-methoxy-phenyl)propan-1-one
MLS000776976
MLS001049078
CHEMBL452723
SCHEMBL1396833
DTXSID2075057
FBGXENQFSMMBNY-UHFFFAOYSA-
HMS2268J24
NSC16691
BBL028691
STL371294
AKOS006242091
CS-W021234
DS-2727
FH67519
FS-3737
NCGC00246236-01
NCGC00246236-02
AC-15466
DB-044494
1-(3-Methoxy-4-hydroxyphenyl)-1-propanone
1-Propanone, 1-(4-hydroxy-3-methoxyphenyl)
1-[4-hydroxy-3-(methyloxy)phenyl]-1-propanone
A812789
1-(4-hydroxy-3-methoxy-phenyl)propan-1-one;1-(4-Hydroxy-3-methoxyphenyl)propan-1-one
InChI=1/C10H12O3/c1-3-8(11)7-4-5-9(12)10(6-7)13-2/h4-6,12H,3H2,1-2H3