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3,5-Diiodo-4-hydroxyacetophenone

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Identification
Molecular formula
C8H6I2O2
CAS number
13329-34-5
IUPAC name
1-(4-hydroxy-3,5-diiodo-phenyl)ethanone
State
State

At room temperature, 3,5-Diiodo-4-hydroxyacetophenone is a solid. It remains stable under normal conditions and does not decompose easily when stored properly.

Melting point (Celsius)
164.00
Melting point (Kelvin)
437.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
388.94g/mol
Molar mass
388.9370g/mol
Density
3.0700g/cm3
Appearence

3,5-Diiodo-4-hydroxyacetophenone appears as a pale yellow to beige crystalline solid. The compound forms fine, crystalline particles and may exhibit a slight iodine odor due to its diiodo content.

Comment on solubility

Solubility of 1-(4-hydroxy-3,5-diiodo-phenyl)ethanone

The solubility of 1-(4-hydroxy-3,5-diiodo-phenyl)ethanone in various solvents is an interesting aspect to explore. Due to its complex structure, particularly the presence of two iodine atoms and a hydroxy group, its solubility characteristics exhibit some intriguing features:

  • Polar Solvents: The hydroxyl group suggests a level of polarity, which can enhance solubility in polar solvents like water and alcohols.
  • Non-Polar Solvents: However, the presence of heavy iodine atoms may inhibit solubility in strictly non-polar solvents such as hexane or benzene. They may not sufficiently disrupt the intermolecular forces.
  • Temperature Effect: As with many organic compounds, an increase in temperature could also promote solubility by increasing molecular motion.
  • Concentration Considerations: At certain concentrations, solubility may reach a saturation point, beyond which precipitation can occur.

In conclusion, while 1-(4-hydroxy-3,5-diiodo-phenyl)ethanone displays variability in solubility based on solvent type and conditions, it is primarily expected to have enhanced solubility in polar environments due to its functional groups. Thus, understanding these interactions is essential for practical applications in chemical processes.

Interesting facts

Interesting Facts about 1-(4-hydroxy-3,5-diiodo-phenyl)ethanone

This compound belongs to the family of halogenated phenols, which are known for their diverse applications in various fields such as pharmaceuticals, agrochemicals, and materials science. The intriguing aspect of 1-(4-hydroxy-3,5-diiodo-phenyl)ethanone lies in its unique chemical structure and the influence of its halogen atoms:

  • Halogen Influence: The presence of iodine atoms in the molecular structure significantly increases the compound's reactivity and molecular stability. This can lead to various interesting chemical behaviors, especially in reactions involving electrophiles.
  • Biological Activity: Compounds with hydroxyl and halogen substituents often exhibit considerable biological activity. This particular compound has potential as a candidate for research in medicinal chemistry, where it may demonstrate antibacterial or anticancer properties.
  • Synthesis Interest: The synthesis of halogenated intermediates can be a challenge, making this compound a valuable target for organic synthesis methodologies, such as electrophilic aromatic substitution.
  • Environmental Considerations: Like many halogenated compounds, 1-(4-hydroxy-3,5-diiodo-phenyl)ethanone can be subject to environmental scrutiny due to the persistence and potential toxicity of its halogenated derivatives.

In a world increasingly focused on sustainable chemistry, the study of such halogenated compounds is crucial. As noted by researchers, “Understanding the properties and potential applications of halogenated compounds opens the door to innovations in materials and pharmaceuticals.” This compound exemplifies a broader category of biologically and chemically important molecules that continue to inspire scientific inquiry.


Ultimately, 1-(4-hydroxy-3,5-diiodo-phenyl)ethanone serves as both a fascinating subject of study and a reminder of the importance of responsible chemical research.

Synonyms
1-(4-hydroxy-3,5-diiodophenyl)ethanone
7191-55-1
1-(4-hydroxy-3,5-diiodophenyl)ethan-1-one
SCHEMBL13624841
4-hydroxy-3,5-di-iodoacetophenone
STL170287
AKOS001577694
1-(4-Hydroxy-3,5-diiodo-phenyl)-ethanone
AK-968/40133901
SR-01000106326
1-(4-HYDROXY-3,5-DIIODOPHENYL)-1-ETHANONE
SR-01000106326-1