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4-Aminoacetophenone oxime

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Identification
Molecular formula
C8H9N1O2
CAS number
2718-89-9
IUPAC name
1-[4-(hydroxyamino)phenyl]ethanone
State
State

At room temperature, 4-Aminoacetophenone oxime is typically found in a solid state.

Melting point (Celsius)
152.50
Melting point (Kelvin)
425.65
Boiling point (Celsius)
389.50
Boiling point (Kelvin)
662.65
General information
Molecular weight
151.17g/mol
Molar mass
151.1730g/mol
Density
1.2466g/cm3
Appearence

4-Aminoacetophenone oxime typically appears as a white to light yellow crystalline solid. It is relatively stable under normal conditions but may discolor upon prolonged exposure to light and air.

Comment on solubility

Solubility of 1-[4-(hydroxyamino)phenyl]ethanone

The solubility of 1-[4-(hydroxyamino)phenyl]ethanone can be influenced by several factors including temperature, pH, and the presence of other solutes. This compound, which features a hydroxyamino functional group, exhibits unique solubility characteristics:

  • Polar Nature: Due to the presence of the hydroxyamino group, the compound tends to be more polar, enhancing its solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds with water molecules significantly increases its solubility, allowing it to dissolve readily.
  • pH Dependency: The solubility may vary with pH, primarily due to the ionization of the amino group at different pH levels, affecting its interaction with the solvent.
  • Temperature Influence: An increase in temperature generally leads to increased solubility for many organic compounds, including this one, as higher temperatures facilitate molecular motion and interactions with the solvent.

In summary, the solubility of 1-[4-(hydroxyamino)phenyl]ethanone in aqueous solutions is supported by its polar character and the capacity for hydrogen bonding, making it an intriguing compound for further exploration in solubility studies.

Interesting facts

Interesting Facts about 1-[4-(hydroxyamino)phenyl]ethanone

1-[4-(hydroxyamino)phenyl]ethanone, often regarded for its intriguing chemical structure, presents a wealth of information for both seasoned chemists and students alike. This compound is noteworthy due to its potential applications and biological relevance.

  • Biological Role: This compound contains a hydroxyamino functional group which is known for its involvement in various biological processes. It is believed to act as a precursor in the synthesis of more complex organic molecules.
  • Medicinal Chemistry: Compounds with similar structures have been studied for their antitumor and antibacterial properties. This makes research around 1-[4-(hydroxyamino)phenyl]ethanone quite relevant in the field of drug development.
  • Chemical Reactivity: The presence of both the hydroxy and amino groups within the structure contributes to its reactivity. Understanding these properties can aid in predicting how it might interact with other chemical species.
  • Hydrogen Bonding: The hydroxy group is capable of forming strong hydrogen bonds, which can play a critical role in the solvation and stability of the compound in various environments.
  • Research Potential: As a part of ongoing chemical research, this compound may inspire new derivatives that can have enhanced biological activities or lower toxicity profiles.

In summary, 1-[4-(hydroxyamino)phenyl]ethanone exemplifies how seemingly simple compounds can hold a treasure trove of information for scientific investigation. Its unique properties offer pathways for both academic research and practical applications in the medical field.

Synonyms
4-Hydroxylaminoacetophenone
1-(4-(Hydroxyamino)phenyl)ethanone
CCRIS 5067
1-[4-(hydroxyamino)phenyl]ethanone
4'-(Hydroxylamino)acetophenone
N-(p-Acetylphenyl)hydroxylamine
BRN 2206858
Ethanone, 1-(4-(hydroxyamino)phenyl)-
ACETOPHENONE, 4'-(HYDROXYAMINO)-
DTXSID20146994
4-15-00-00037 (Beilstein Handbook Reference)
Ethanone, 1-[4-(hydroxyamino)phenyl]-
DTXCID3069485
Ethanone, 1-(4-(hydroxyamino)phenyl)-(9CI)
10517-47-2
Ethanone, 1-[4-(hydroxyamino)phenyl]-
SCHEMBL6771376
SCHEMBL11406233