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Ibuprofen

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Identification
Molecular formula
C13H18O2
CAS number
15687-27-1
IUPAC name
1-(4-hydroxyphenyl)-4-isopropyl-2-phenyl-pyrazolidine-3,5-dione
State
State

At room temperature, ibuprofen is typically a solid in the form of a white crystalline powder.

Melting point (Celsius)
76.00
Melting point (Kelvin)
349.15
Boiling point (Celsius)
157.00
Boiling point (Kelvin)
430.15
General information
Molecular weight
206.28g/mol
Molar mass
206.2820g/mol
Density
1.1740g/cm3
Appearence

Ibuprofen typically appears as a white crystalline powder or crystal. It is often distributed in tablet or capsule form for medicinal use. The powder has a slightly acidic odor.

Comment on solubility

Solubility Analysis of 1-(4-hydroxyphenyl)-4-isopropyl-2-phenyl-pyrazolidine-3,5-dione

The solubility of 1-(4-hydroxyphenyl)-4-isopropyl-2-phenyl-pyrazolidine-3,5-dione in various solvents can exhibit distinct characteristics based on its structural components. Understanding the solubility is vital for applications in pharmaceuticals and chemical synthesis. Here are some key points regarding its solubility:

  • Solvent Compatibility: This compound is likely to dissolve readily in polar solvents due to its hydroxyl group, enhancing hydrogen bonding interactions.
  • Apolar Solvents: Solubility in non-polar solvents may be limited since the presence of the polar hydroxyl group can hinder consistent interaction with such media.
  • Temperature Effects: An increase in temperature might enhance solubility in various solvents, which is a common phenomenon observed for many organic compounds.
  • pH Influence: The solubility could also change with pH, especially since it contains a hydroxyl group that can ionize under certain conditions.

In summary, while 1-(4-hydroxyphenyl)-4-isopropyl-2-phenyl-pyrazolidine-3,5-dione may show considerable solubility in polar solvents, its behavior in non-polar environments tends to be less favorable. The compound's solubility properties underscore the significance of solvent choice in practical applications, where solubility can directly impact its efficacy and performance.

Interesting facts

Interesting Facts about 1-(4-hydroxyphenyl)-4-isopropyl-2-phenyl-pyrazolidine-3,5-dione

This fascinating compound belongs to the class of pyrazolidines, which are known for their diverse biological activities. It features an intriguing multi-ring structure that contributes to its properties. Here are some engaging facts to consider:

  • Pharmacological Relevance: Compounds in the pyrazolidine family have been explored for their anti-inflammatory and analgesic properties, making them of significant interest in medical research.
  • Hydroxyl Groups: The presence of a hydroxyl group on the benzene ring enhances the compound's reactivity and solubility, which can affect bioavailability.
  • Isopropyl Substituent: The isopropyl group plays a crucial role in modulating the compound's lipophilicity, influencing how it behaves in biological systems.
  • Phenyl Rings: The inclusion of phenyl groups in the structure can lead to varied interactions with biological targets, promoting further exploration for therapeutic agents.
  • Research Insights: Studies on pyrazolidine derivatives have paved the way for developing new medications, showcasing their potential in treating conditions like arthritis and chronic pain.

In conclusion, 1-(4-hydroxyphenyl)-4-isopropyl-2-phenyl-pyrazolidine-3,5-dione exemplifies a structurally rich compound that invites further investigation. As researchers continue to explore its capabilities, we may uncover even more exciting applications in the realm of pharmaceuticals!

Synonyms
1-(p-Hydroxyphenyl)-4-isopropyl-2-phenyl-3,5-pyrazolidinedione
14845-08-0
G 35716
3,5-Pyrazolidinedione, 1-(p-hydroxyphenyl)-4-isopropyl-2-phenyl-
1-Phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-isopropylpyrazolidin [German]
DTXSID50933415
1-Phenyl-2-(p-hydroxyphenyl)-3,5-dioxo-4-isopropylpyrazolidin
1-(4-Hydroxyphenyl)-2-phenyl-4-(propan-2-yl)pyrazolidine-3,5-dione