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Phenylbutazone

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Identification
Molecular formula
C19H20N2O2
CAS number
50-33-9
IUPAC name
1-(4-hydroxyphenyl)-4-pentyl-2-phenyl-pyrazolidine-3,5-dione
State
State

At room temperature, Phenylbutazone is in a solid crystalline state. It is typically stable under normal conditions.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
310.00
Boiling point (Kelvin)
583.15
General information
Molecular weight
308.37g/mol
Molar mass
308.3680g/mol
Density
1.2200g/cm3
Appearence

Phenylbutazone appears as a white to off-white crystalline powder. It is often found in solid form with no pronounced odor. The crystalline nature allows it to form fine particles easily.

Comment on solubility

Solubility of 1-(4-hydroxyphenyl)-4-pentyl-2-phenyl-pyrazolidine-3,5-dione

The solubility of the compound 1-(4-hydroxyphenyl)-4-pentyl-2-phenyl-pyrazolidine-3,5-dione in various solvents can be quite complex due to its intricate molecular structure. Understanding the solubility characteristics of such a compound involves considering several factors:

  • Polarity: The presence of the hydroxyl group (-OH) contributes to the compound's ability to interact with polar solvents such as water. Generally, compounds with functional groups that can participate in hydrogen bonding tend to exhibit greater solubility in polar solvents.
  • Hydrophobic Chain: The pentyl chain provides a hydrophobic character which may limit its solubility in water but enhances solubility in non-polar organic solvents like hexane or toluene.
  • Functional Groups: Aside from the hydroxyl group, the additional phenyl rings can influence solubility due to π-π stacking interactions, making the compound more soluble in aromatic solvents.
  • Temperature Dependency: Like many organic compounds, solubility can increase with temperature, allowing for greater interaction between solvent and solute.

In summary, 1-(4-hydroxyphenyl)-4-pentyl-2-phenyl-pyrazolidine-3,5-dione likely exhibits varying solubility depending on the solvent choice due to its balance of hydrophilic and hydrophobic features. Nonetheless, to determine its exact solubility profile, empirical testing in different solvents under controlled conditions is recommended.

Interesting facts

Interesting Facts about 1-(4-Hydroxyphenyl)-4-pentyl-2-phenyl-pyrazolidine-3,5-dione

1-(4-Hydroxyphenyl)-4-pentyl-2-phenyl-pyrazolidine-3,5-dione is a fascinating compound that belongs to the pyrazolidine class of molecules. Here are some intriguing points regarding this compound:

  • Pharmacological Relevance: This compound exhibits potential biological activity. Compounds with similar structures are often explored for their anti-inflammatory and analgesic properties.
  • Structural Complexity: The unique architecture of this molecule incorporates a pyrazolidine ring system along with various substituents, contributing to its diverse chemical behavior and potential reactivity.
  • Hydroxyl Group Impacts: The presence of the hydroxyl group (-OH) at the para position of the phenyl ring can influence the compound's solubility and interaction with biological targets, which is critical for its potential therapeutic applications.
  • Versatile Synthetic Routes: The synthesis of compounds in the pyrazolidine family is of great interest in organic chemistry. The starting materials and reaction pathways can vary significantly, allowing chemists to explore innovative synthesis techniques.
  • Research Applications: This compound may also serve as a precursor or building block in the development of new drug candidates, providing a valuable material for medicinal chemistry research.

As research progresses, the understanding of the unique properties and mechanisms of compounds like 1-(4-hydroxyphenyl)-4-pentyl-2-phenyl-pyrazolidine-3,5-dione may lead to exciting discoveries in the field of pharmaceuticals!

Synonyms
Y57CU3W6O9
4-AMYL-2-(P-HYDROXYPHENYL)-1-PHENYL-3,5-PYRAZOLIDINEDIONE
22204-76-8
3,5-Pyrazolidinedione, 1-(4-hydroxyphenyl)-4-pentyl-2-phenyl-
UNII-Y57CU3W6O9
DTXSID70274913
1-(4-hydroxyphenyl)-4-pentyl-2-phenylpyrazolidine-3,5-dione