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NBI-02

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Identification
Molecular formula
C12H11IN6O
CAS number
481836-83-9
IUPAC name
1-(4-iodophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine
State
State

At room temperature, this compound is in a solid state, often presented as a crystalline powder. It is stable under normal conditions but should be handled with care to avoid moisture exposure which can lead to degradation.

Melting point (Celsius)
219.00
Melting point (Kelvin)
492.15
Boiling point (Celsius)
531.80
Boiling point (Kelvin)
804.95
General information
Molecular weight
350.16g/mol
Molar mass
350.1710g/mol
Density
1.6790g/cm3
Appearence

The compound appears as a crystalline solid. It typically manifests in light yellow to off-white colored crystals. It may come in powder form depending on the synthesis and processing methods used.

Comment on solubility

Solubility of 1-(4-iodophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine

The solubility of 1-(4-iodophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine is influenced by various factors, primarily due to its complex molecular structure. Here are some key points regarding its solubility:

  • Polarity: The presence of a guanidine functional group generally suggests a degree of polarity which could enhance solubility in polar solvents like water.
  • Aromatic Behavior: The aromatic 4-iodophenyl group may render the compound less soluble in polar solvents due to its hydrophobic nature.
  • Hydrogen Bonding: The ability to form hydrogen bonds from guanidine could lead to increased interaction with solvents, potentially improving solubility in organic solvents.
  • Solvent Interaction: Solubility may vary significantly in different solvents. It is critical to test solubility in various organic solvents and water to determine the most suitable application approaches.

In summary, while the compound has traits that may contribute to solubility in certain environments, understanding the balance between hydrophilic and hydrophobic elements is crucial. As the saying goes, "Like dissolves like," emphasizing the importance of solvent choice for this unique compound.

Interesting facts

Interesting Facts about 1-(4-Iodophenyl)-2-(6-methyl-4-oxo-1H-pyrimidin-2-yl)guanidine

This compound is a fascinating member of the guanidine family, characterized by its complex structure and potential for varied biological activity. Here are some notable details to consider:

  • Structure and Substituents: The presence of a 4-iodophenyl group contributes to the compound's unique chemical reactivity. This halogen substitution allows for a range of interactions in biological systems, potentially enhancing its medicinal properties.
  • Pyrimidine Moiety: The 6-methyl-4-oxo-1H-pyrimidin-2-yl part of the structure suggests interesting pharmacological profiles, as pyrimidines are often found in pharmaceuticals, including antimetabolites and antiviral agents.
  • Research Potential: Compounds like this one are actively studied for their role in drug development. The guanidine functional group is known for its ability to mimic functionalities in nucleobases, thus having implications in biological applications.
  • Biological Applications: Researchers are exploring derivatives of such compounds for use in treatments against various diseases, including cancer and viral infections.
  • Synthesis and Modification: The intricate structure allows for various synthetic pathways, making it an interesting target for chemists aiming to create analogs with enhanced efficacy or reduced side effects.

As quoted in many literature reviews, “the design of novel compounds with specific biological activities is at the heart of medicinal chemistry.” This compound stands as an elegant example of how structural intricacies can lead to significant advancements in therapeutic strategies.