ISOQUINOLINE DERIVATIVE | Solubility of Things

Identification

Molecular formula

C₂₀H₂₅NO₄S

CAS number

Not available

IUPAC name

1-(4-isopropylsulfonylphenyl)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline

State

At room temperature, this compound is typically a solid.

Melting point (Celsius)

170.00

Melting point (Kelvin)

443.15

Boiling point (Celsius)

478.00

Boiling point (Kelvin)

751.15

General information

Molecular weight

387.50g/mol

Molar mass

387.4950g/mol

Density

1.2100g/cm³

Appearence

The compound appears as a white to off-white crystalline powder. Its morphological properties might include fine, needle-like or granular crystals, depending on the specific synthesis conditions and purification processes.

Comment on solubility

Solubility of 1-(4-Isopropylsulfonylphenyl)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline

The solubility of 1-(4-isopropylsulfonylphenyl)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline can be influenced by several factors, making it a subject of interest in chemical studies. Here are some key points to consider:

Polarity: The presence of multiple methoxy groups enhances its polarity, which generally increases solubility in polar solvents like water.
Functional Groups: The isopropylsulfonyl group and the isoquinoline structure can play a significant role in solubility. Functional groups can engage in hydrogen bonding and interact with the solvent.
Solvent Considerations: This compound is likely to be soluble in organic solvents such as ethanol, dimethyl sulfoxide (DMSO), and acetone, but may have limited solubility in nonpolar solvents.
Temperature Effects: Increasing temperature may enhance the solubility of solids in liquids, potentially making the compound more soluble at elevated temperatures.

In conclusion, while 1-(4-isopropylsulfonylphenyl)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline may exhibit moderate solubility characteristics, the interaction between its chemical structure and various solvents is crucial for understanding its behavior in solution. This illustrates the importance of tailoring solvent selection to optimize solubility for applications in chemical research and drug formulation.

Interesting facts

Interesting Facts about 1-(4-Isopropylsulfonylphenyl)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline

This compound, with its intricate structure, illustrates the fascinating world of isoquinoline derivatives, which are pivotal in medicinal chemistry. Here are some engaging insights:

Potential Biological Activity: Isoquinolines are known for their varied pharmacological properties, including anti-inflammatory, antimicrobial, and anticancer activities. The unique substitutions on this compound may enhance its biological efficacy.
Structural Complexity: The presence of a sulfonyl group and dimethoxy substituents adds layers of complexity, which can influence how the molecule interacts with biological targets.
Medicinal Applications: Research into isoquinoline derivatives has led to the development of several pharmaceutical agents. Compounds like this are often studied for their potential to treat neurological disorders and chronic pain.
Importance in Synthesis: The synthetic pathways leading to compounds like this often involve multi-step processes that incorporate advanced techniques in organic synthesis, showcasing the ingenuity of chemists.
Research Interest: This compound is indicative of ongoing research to discover new therapeutic agents, reaffirming the importance of studying complex molecules in the quest for novel treatments.

In summary, 1-(4-isopropylsulfonylphenyl)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinoline serves as a remarkable example of how complex organic compounds can be at the forefront of medicinal innovation. As researchers continue to explore its properties, we may uncover more about its potential uses and applications in healthcare.