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1-(4-isopropylsulfonylphenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline

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Identification
Molecular formula
C19H23NO4S
CAS number
186810-28-8
IUPAC name
1-(4-isopropylsulfonylphenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline
State
State

At room temperature, this compound is in a solid state. It is stable under standard conditions but should be stored in a dry place to prevent any potential decomposition or reaction with moisture.

Melting point (Celsius)
158.60
Melting point (Kelvin)
431.80
Boiling point (Celsius)
595.40
Boiling point (Kelvin)
868.60
General information
Molecular weight
345.43g/mol
Molar mass
345.4260g/mol
Density
1.3012g/cm3
Appearence

The compound is a crystalline solid. It appears as a white to slightly off-white powder and is typically characterized by its high purity and fine grain size. The crystalline structure contributes to its overall stability and ease of handling.

Comment on solubility

Solubility of 1-(4-isopropylsulfonylphenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline

The solubility of 1-(4-isopropylsulfonylphenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline can be influenced by various factors due to its complex structure. Here are some key points to consider:

  • Solvent Interaction: This compound may show varying solubility in different solvents such as:
    • Polar solvents (e.g., water, methanol) may offer limited solubility due to its relatively large and hydrophobic structure.
    • Non-polar solvents (e.g., chloroform, hexane) may enhance solubility owing to lower polarity.
  • Influence of Temperature: Increasing the temperature generally increases the solubility of solids; hence, higher temperatures might promote dissolution in suitable solvents.
  • pH Sensitivity: If the compound has ionizable groups, its solubility could be pH-dependent, whereby adjustments in pH may significantly enhance or inhibit solubility.
  • Structural Characteristics: The presence of sulfonyl groups generally enhances solubility due to their ability to stabilize ionic forms or facilitate hydrogen bonding.

In conclusion, understanding the solubility of this compound requires a comprehensive analysis of its molecular interactions and environmental conditions. Experimentation is often essential to accurately determine solubility profiles in various media.

Interesting facts

Interesting Facts about 1-(4-isopropylsulfonylphenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline

1-(4-isopropylsulfonylphenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline is a fascinating compound with intriguing potential applications in medicinal chemistry. As a derivative of isoquinoline, a well-known bicyclic structure, it showcases the versatility of heterocyclic compounds in drug development. Here are some key highlights:

  • Pharmacological Implications: This compound is being investigated for its potential role as a therapeutic agent, particularly in treating neurological disorders. Compounds with isoquinoline structures have been associated with various biological activities, including anti-inflammatory and neuroprotective effects.
  • Structural Complexity: The presence of the sulfonyl group and dimethoxy substitutions contributes to the overall molecular diversity. These modifications can significantly influence the compound's solubility, permeability, and interaction with biological targets, highlighting the importance of structure-activity relationships in drug design.
  • Applications in Research: Researchers are exploring its utility as a scaffold for the development of novel drugs. Such compounds might lead to breakthroughs in understanding and managing chronic conditions or enhancing cognitive functions.
  • Natural Product Inspiration: The core isoquinoline structure is prevalent in many natural products, some of which exhibit notable biological effects. This connection underlines the importance of synthetic analogs in pharmaceuticals.
  • Future Exploration: As drug discovery progresses, compounds like this one offer promising avenues for further investigation. Studies on its mechanism of action and interaction with specific receptors could pave the way for new therapeutic strategies.

In summary, 1-(4-isopropylsulfonylphenyl)-6,7-dimethoxy-3,4-dihydroisoquinoline is more than just a chemical compound; it represents a significant chapter in the quest for innovative medications that address complex health challenges. As is often said in the scientific community, "The right molecules can lead to the right therapies."

Synonyms
BRN 1505735
ISOQUINOLINE, 3,4-DIHYDRO-1-(p-(ISOPROPYLSULFONYL)PHENYL)-6,7-DIMETHOXY-
18453-36-6
DTXSID60171588
1-((p-Isopropylsulfonyl)phenyl)-6,7-dimethoxy-3,4-dihydro-isoquinoline
3,4-Dihydro-1-(p-(isopropylsulfonyl)phenyl)-6,7-dimethoxy-isoquinoline
5-21-05-00646 (Beilstein Handbook Reference)
DTXCID0094079