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Lidocaine hydrochloride

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Identification
Molecular formula
C14H23ClN2O2
CAS number
6108-05-0
IUPAC name
1-[4-methoxy-2-(2-piperidin-1-ium-1-ylethoxy)phenyl]butan-1-one;chloride
State
State

At room temperature, lidocaine hydrochloride is in a solid state. It is typically used in a powdered form in pharmaceutical applications, where it's utilized as a local anesthetic.

Melting point (Celsius)
80.00
Melting point (Kelvin)
353.15
Boiling point (Celsius)
390.00
Boiling point (Kelvin)
663.15
General information
Molecular weight
288.82g/mol
Molar mass
288.8200g/mol
Density
1.1060g/cm3
Appearence

Lidocaine hydrochloride appears as a white to off-white crystalline powder. Its appearance is quite typical for many solid organic compounds used in pharmaceutical applications.

Comment on solubility

Solubility of 1-[4-methoxy-2-(2-piperidin-1-ium-1-ylethoxy)phenyl]butan-1-one;chloride

The solubility of this compound is influenced by several structural characteristics. Notably, the presence of the piperidine ring contributes to its solubility profile in various solvents.

  • Aromatic character: The substitution on the aromatic ring can enhance compatibility with organic solvents.
  • Ionic characteristics: The chloride component can lead to increased solubility in polar solvents such as water due to ion-dipole interactions.
  • Functional groups: The methoxy group provides some hydrophilicity, which may facilitate dissolution in water-based solutions.

In summary, this compound is likely to exhibit moderate to high solubility in polar solvents like water due to the ionic nature of the chloride and the addition of hydrophilic groups, while potentially showing better solubility in organic solvents due to its aromatic structure. As such, you'll find that “the solubility varies significantly depending on the solvent environment.”

Interesting facts

Interesting Facts about 1-[4-methoxy-2-(2-piperidin-1-ium-1-ylethoxy)phenyl]butan-1-one;chloride

1-[4-methoxy-2-(2-piperidin-1-ium-1-ylethoxy)phenyl]butan-1-one;chloride is a fascinating compound that has drawn the attention of researchers in various fields. Here are some intriguing facts:

  • Pharmacological Interest: This compound is notable for its potential use in pharmaceuticals. The presence of the piperidine moiety is linked to a variety of biological activities, making it a subject of interest in medicinal chemistry.
  • Structure Diversity: The compound features a unique structure that combines aromatic and aliphatic components, providing a versatile scaffold for further chemical modifications and derivative syntheses.
  • Possible Applications: Due to its structural attributes, it could be explored for applications in drug development, particularly those involving neurological or psychotropic effects.
  • Ionization Properties: The piperidin-1-ium group in the compound suggests interesting ionization properties, which can influence its interactions with biological targets, potentially affecting its pharmacodynamics.
  • Research Trends: As an emerging compound in the field of organic chemistry, ongoing research may reveal novel applications in areas such as neuroscience, biochemistry, and synthetic chemistry.

Exploring compounds like 1-[4-methoxy-2-(2-piperidin-1-ium-1-ylethoxy)phenyl]butan-1-one;chloride not only enhances our understanding of chemical interactions but also opens new avenues for innovations in various scientific domains.

Synonyms
Butyrophenone, 4'-methoxy-6'-(2-piperidinoethoxy)-, hydrochloride
4'-Methoxy-2'-(2-piperidinoethoxy)butyrophenone hydrochloride
BUTYROPHENONE, 4'-METHOXY-2'-(2-PIPERIDINOETHOXY)-, HYDROCHLORIDE
20800-19-5
RefChem:331438