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4-Methoxy-3-methylacetophenone

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Identification
Molecular formula
C10H12O2
CAS number
5785-63-5
IUPAC name
1-(4-methoxy-3-methyl-phenyl)ethanone
State
State

At room temperature, 4-Methoxy-3-methylacetophenone is typically in a solid state. Its crystalline nature can vary from lumps to powder based on physical handling.

Melting point (Celsius)
37.00
Melting point (Kelvin)
310.00
Boiling point (Celsius)
259.00
Boiling point (Kelvin)
532.00
General information
Molecular weight
164.20g/mol
Molar mass
164.2040g/mol
Density
1.0340g/cm3
Appearence

4-Methoxy-3-methylacetophenone is a white to slightly yellow crystalline solid. It is often encountered as powder or crystalline lumps and can be characterized by its slightly sweet odor.

Comment on solubility

Solubility of 1-(4-methoxy-3-methyl-phenyl)ethanone (C10H12O2)

The solubility of 1-(4-methoxy-3-methyl-phenyl)ethanone is influenced by its molecular structure, which plays a crucial role in how it interacts with solvents. Understanding its solubility can be particularly relevant for applications in chemistry and pharmaceuticals.

Key Points about Solubility:

  • Polar vs. Nonpolar Solvents: The presence of the methoxy group (-OCH3) allows for some degree of polarity, which can enhance solubility in polar solvents like ethanol or methanol.
  • Hydrophobic Character: The sizable aromatic ring adds a hydrophobic character, making it less soluble in nonpolar solvents such as hexane or toluene.
  • Concentration Dependence: It's important to note that its solubility can vary significantly with concentration, temperature, and the presence of other solutes.
  • Interactions: Potential hydrogen bonding with polar solvents may increase solubility compared to completely nonpolar environments.

In summary, while 1-(4-methoxy-3-methyl-phenyl)ethanone demonstrates a tendency to dissolve in polar solvents due to its molecular structure, it is less favorable in nonpolar environments. Understanding these solubility properties is essential for effective utilization in various chemical contexts.

Interesting facts

Interesting Facts about 1-(4-methoxy-3-methyl-phenyl)ethanone

1-(4-methoxy-3-methyl-phenyl)ethanone, often referred to as a derivative of acetophenone, is a fascinating compound with a variety of applications in both science and industry. Here are some intriguing points to consider:

  • Fragrance and Flavor: This compound is frequently used in the formulation of fragrances and flavoring agents due to its sweet, floral aroma.
  • Synthetic Pathways: It can be synthesized through various methodologies, often involving the alkylation of phenolic compounds. This showcases the versatility of organic synthesis techniques.
  • Analytical Applications: 1-(4-methoxy-3-methyl-phenyl)ethanone can be utilized as an internal standard in mass spectrometry, aiding in the quantification of other compounds.
  • Research Interest: The compound has gained popularity in medicinal chemistry for its potential biological activities, including antitumor and anti-inflammatory properties.

In essence, the study of 1-(4-methoxy-3-methyl-phenyl)ethanone offers a glimpse into the diverse realms of organic chemistry, medicinal applications, and the significant role of compounds derived from natural substances. As a testament to the complexity of organic molecules, it underscores the blend of art and science that shapes modern chemistry.

As renowned chemist Linus Pauling once said, "Chemistry is the science of substances, their structure, composition, and transformations." This compound exemplifies that philosophy perfectly.

Synonyms
1-(4-methoxy-3-methylphenyl)ethanone
1-(4-methoxy-3-methylphenyl)ethan-1-one
831-609-7
10024-90-5
3'-Methyl-4'-methoxyacetophenone
Ethanone, 1-(4-methoxy-3-methylphenyl)-
4'-methoxy-3'-methylacetophenone
4-Methoxy-3-methylacetophenone
ACETOPHENONE, 4'-METHOXY-3'-METHYL-
1-(4-methoxy-3-methyl-phenyl)-ethanone
F2146-0685
BRN 2244910
AI3-10516
MFCD01673307
3-Iodo-4-methoxyacetophenone
4-08-00-00477 (Beilstein Handbook Reference)
SCHEMBL195793
3-Methyl-4-methoxyacetophenone
SCHEMBL2095221
SCHEMBL8804468
4 -Methoxy-3-methylacetophenone
DTXSID20143049
SRPCRBVBOIYYHS-UHFFFAOYSA-N
SMSSF-0533444
KAA02490
(4 methoxy-3-methylphenyl)-ethanone
1-(4-methoxy-3-tolyl)-1-ethanone
1-(3-methyl-4-methoxyphenyl)ethanone
AKOS000346365
1-(4-methoxy-3-methylphenyl)-ethanone
AS-19671
DA-16654
CS-0105545
EN300-118793
Z415732058