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N-Acetyl-4-methoxypyrrolidinone

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Identification
Molecular formula
C12H13NO3
CAS number
21806-61-1
IUPAC name
1-(4-methoxybenzoyl)pyrrolidin-2-one
State
State
The compound is usually found in a solid state at room temperature. It is stable under standard conditions and retains its structure without decomposing.
Melting point (Celsius)
119.80
Melting point (Kelvin)
392.90
Boiling point (Celsius)
363.60
Boiling point (Kelvin)
636.80
General information
Molecular weight
191.24g/mol
Molar mass
191.2110g/mol
Density
1.1810g/cm3
Appearence

N-Acetyl-4-methoxypyrrolidinone typically appears as a white crystalline solid under standard conditions. It may be available in powdered form and is known for its characteristic chemical structure that includes a methoxybenzoyl group attached to a pyrrolidinone ring.

Comment on solubility

Solubility of 1-(4-methoxybenzoyl)pyrrolidin-2-one

The compound 1-(4-methoxybenzoyl)pyrrolidin-2-one (C12H13NO3) exhibits interesting solubility characteristics that can influence its applications. Understanding its solubility is crucial for its potential use in various chemical and pharmaceutical processes.

General Solubility Trends

In general, solubility is affected by several factors, including:

  • Polarity: The greater the polarity of a compound, the more likely it is to dissolve in polar solvents such as water.
  • Functional Groups: The presence of groups such as hydroxyl (-OH) or carbonyl (>C=O) can enhance solubility in polar solvents.
  • Molecular Weight: Higher molecular weights can lead to decreased solubility due to increased intermolecular forces.

For 1-(4-methoxybenzoyl)pyrrolidin-2-one:

  • It possesses a methoxy group, which generally increases solubility in organic solvents.
  • The presence of a pyrrolidinone ring and carbonyl functionalities might afford moderate solubility in both polar and nonpolar solvents.
  • However, its overall solubility in water is likely limited due to its larger hydrophobic carbon backbone.

Solubility in Common Solvents

Based on its structure, 1-(4-methoxybenzoyl)pyrrolidin-2-one is expected to:

  • Dissolve well in: Organic solvents such as ethanol, methanol, or acetone.
  • Have limited solubility in: Aqueous solutions, possibly requiring co-solvents or conditions such as heating to enhance dissolution.

In summary, while 1-(4-methoxybenzoyl)pyrrolidin-2-one shows promise for solubility in various solvents, its utilization for specific applications may require further investigation of conditions to optimize its solubility properties. Understanding these characteristics can help in tailoring its functionalities in chemical formulations.

Interesting facts

Exploring 1-(4-Methoxybenzoyl)pyrrolidin-2-one

1-(4-Methoxybenzoyl)pyrrolidin-2-one is a fascinating compound that belongs to the class of pyrrolidinones, which are notable for their versatile applications in pharmaceuticals and organic synthesis. This molecular structure consists of a pyrrolidine ring substituted with a 4-methoxybenzoyl group, making it intriguing in the world of chemistry.

Key Features and Applications

  • Pharmaceutical Potential: Compounds like 1-(4-methoxybenzoyl)pyrrolidin-2-one often exhibit bioactive properties that can be explored for drug development.
  • Research Significance: The presence of the methoxy group can influence the compound's pharmacokinetics, making it a point of interest for medicinal chemists.
  • Synthetic Utility: The structure provides a reactive site for further functionalization, allowing chemists to create a variety of derivatives for diverse applications.

This compound’s unique structure often leads to discussions about its reactivity and potential therapeutic applications. As students and scientists delve deeper into the realms of organic chemistry, compounds like this serve as vital stepping stones towards the development of novel materials and medications.

Did You Know?

  • The incorporation of methoxy groups in organic molecules can enhance solubility and bioavailability, which is crucial in drug formulation.
  • Pyrrolidinone derivatives are often explored for their potential in treating neurological disorders due to their ability to cross the blood-brain barrier.
  • 1-(4-Methoxybenzoyl)pyrrolidin-2-one provides a rich canvas for synthetic chemists to innovate and create compounds with optimized properties.

In summary, 1-(4-methoxybenzoyl)pyrrolidin-2-one is more than just a chemical entity—it embodies the intersection of creativity and scientific inquiry in the world of chemistry.

Synonyms
aniracetam
72432-10-1
Draganon
Sarpul
1-(4-methoxybenzoyl)pyrrolidin-2-one
1-(4-Methoxybenzoyl)-2-pyrrolidinone
Ampamet
Ro 13-5057
1-p-Anisoyl-2-pyrrolidinone
Aniracetamun
Memodrin
1-anisoyl-2-pyrrolidinone
Aniracetamun [INN-Latin]
Ro-13-5057
1-p-anisoylpyrrolidin-2-one
Aniracetam [USAN:INN:JAN]
1-[(4-methoxyphenyl)carbonyl]pyrrolidin-2-one
MFCD00153767
NSC-758223
Ro 135057
BRN 4807205
2-Pyrrolidinone, 1-(4-methoxybenzoyl)-
DTXSID5045128
CHEBI:47943
5L16LKN964
ANIRACETAM [MI]
ANIRACETAM [INN]
ANIRACETAM [JAN]
1-(p-Methoxybenzoyl)-2-pyrrolidinon [German]
1-(p-Methoxybenzoyl)-2-pyrrolidinon
ANIRACETAM [USAN]
Ro-135057
ANIRACETAM [MART.]
ANIRACETAM [WHO-DD]
MLS000079240
DTXCID3025128
NSC 758223
aniracetam;p-methoxybenzoyl-2-pirrolidone
NCGC00015116-10
SMR000038438
Aniracetamun (INN-Latin)
ANIRACETAM (MART.)
CAS-72432-10-1
1-((4-methoxyphenyl)carbonyl)pyrrolidin-2-one
SR-01000003147
1-(4-Methoxybenzoyl)-2-pyrrolidinone;Ampamet;Draganon
aniracetamum
Reset
UNII-5L16LKN964
Aniracetam ,(S)
Aniracetam (Standard)
Spectrum_001342
Tocris-0867
Aniracetam, >=98%
Opera_ID_294
Spectrum3_001553
Spectrum4_000761
Spectrum5_001609
Lopac-A-9950
Biomol-NT_000222
Lopac0_000115
SCHEMBL70998
BSPBio_003026
KBioGR_001142
KBioSS_001822
MLS000028591
MLS001201800
Aniracetam (JAN/USAN/INN)
CHEMBL36994
DivK1c_000403
SPECTRUM1503078
Aniracetam - Bio-X trade mark
BPBio1_001316
GTPL4133
HMS501E05
KBio1_000403
KBio2_001822
KBio2_004390
KBio2_006958
KBio3_002526
N06BX11
NINDS_000403
BCPP000399
HMS2089O17
HMS2094K07
HMS2234E11
HMS3260G12
HMS3266L08
HMS3411P17
HMS3657G11
HMS3675P17
HMS3713N20
HMS3884C09
Pharmakon1600-01503078
BCP02091
Tox21_110086
Tox21_500115
1-(4-Methoxybenzoyl)-2-pyrrolidone
HB0116
HY-10932R
NSC758223
s1281
1-(p-methoxybenzoyl)-2-pyrrolidinone
AKOS005066313
Tox21_110086_1
AB04115
BCP9000303
CCG-204210
CS-1793
DB04599
FA17937
KS-5313
LP00115
SDCCGSBI-0050103.P005
IDI1_000403
NCGC00015116-01
NCGC00015116-02
NCGC00015116-03
NCGC00015116-04
NCGC00015116-05
NCGC00015116-06
NCGC00015116-07
NCGC00015116-08
NCGC00015116-09
NCGC00015116-11
NCGC00015116-12
NCGC00015116-13
NCGC00015116-24
NCGC00021402-02
NCGC00021402-05
NCGC00021402-06
NCGC00021402-07
NCGC00021402-08
NCGC00260800-01
Ro-13-3057
1-(4-Methoxy-benzoyl)-pyrrolidin-2-one
1-(4-Methoxybenzoyl)-2-pyrrolidinone #
AC-15651
BA164183
HY-10932
SY052612
SBI-0050103.P004
A2394
EU-0100115
NS00017748
SW199095-2
A 9950
D01883
H10883
AB00053303-14
AB00053303_15
AB00053303_16
ANIRACETAM; 1-P-ANISOYL-2-PYRROLIDINONE
A837527
Q417630
SR-01000003147-2
SR-01000003147-4
SR-01000003147-6
SR-01000003147-8
BRD-K88611939-001-02-6
BRD-K88611939-001-13-3
BRD-K88611939-001-22-4
BRD-K88611939-001-23-2
615-758-3