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Metoprolol

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Identification
Molecular formula
C15H25NO3
CAS number
37350-58-6
IUPAC name
1-(4-methoxybutylamino)-3-phenoxy-butan-2-ol
State
State

At room temperature, Metoprolol is in a solid state. It is typically administered in the form of tablets or injectable solutions when used in medical contexts.

Melting point (Celsius)
120.00
Melting point (Kelvin)
393.15
Boiling point (Celsius)
416.00
Boiling point (Kelvin)
689.15
General information
Molecular weight
267.37g/mol
Molar mass
267.3650g/mol
Density
1.0790g/cm3
Appearence

Metoprolol appears as a white to off-white crystalline powder. It is often supplied in tablet form for medicinal use, but the pure substance itself has this crystalline appearance.

Comment on solubility

Solubility of 1-(4-methoxybutylamino)-3-phenoxy-butan-2-ol

The solubility of 1-(4-methoxybutylamino)-3-phenoxy-butan-2-ol can be influenced by various factors, including its molecular structure and the surrounding environment. As a compound that contains both hydrophobic (phenoxy) and hydrophilic (butylamino) groups, its solubility can be quite complex and varies in different solvents:

  • In organic solvents: This compound is likely to be soluble in non-polar to moderately polar organic solvents such as ethanol, methanol, or dimethyl sulfoxide (DMSO) due to the presence of its hydrophobic aromatic groups.
  • In polar solvents: The hydrophilic characteristics provided by the amino groups may allow partial solubility in water, though it may be limited due to bulkiness from the side chains.

Depending on temperature and concentration, the solubility limits can vary significantly. Additionally, it should be noted that factors such as pH and the presence of other ions can also play a critical role in solubility behavior:

  1. pH Effect: The ionization of the amino group can be influenced by the pH of the solution, which may either enhance or reduce solubility in aqueous environments.
  2. Ionic Interactions: The presence of salts in the solvent can stabilize or destabilize the compound, affecting its solubility further.

In summary, while 1-(4-methoxybutylamino)-3-phenoxy-butan-2-ol demonstrates potential solubility in various organic solvents, its precise solubility characteristics will depend on a combination of structural, environmental, and chemical factors. Understanding these variables is crucial for practical applications involving this compound.

Interesting facts

Interesting Facts about 1-(4-methoxybutylamino)-3-phenoxy-butan-2-ol

1-(4-methoxybutylamino)-3-phenoxy-butan-2-ol is a fascinating compound that has garnered attention in the fields of medicinal and organic chemistry. Here are some compelling insights into this compound:

  • Pharmaceutical Relevance: This compound contains structural features that are common in various pharmaceutical agents, making it a potential candidate for drug development.
  • Functional Groups: The presence of a phenoxy group along with an amino group signifies that this compound may exhibit unique biological activities and could serve as a versatile intermediate in organic syntheses.
  • Structure Activity Relationship (SAR): Researchers are continually studying how modifications in the compound’s structure can influence its biological functionality. This kind of research is vital in the discovery of more effective pharmaceuticals.
  • Biological Activity: Some studies suggest that compounds with similar structures exhibit anti-inflammatory and analgesic properties, indicating that 1-(4-methoxybutylamino)-3-phenoxy-butan-2-ol might hold therapeutic potential.
  • Versatility in Synthesis: The synthetic routes to create this compound often involve numerous organic reactions, making it a subject of interest for chemistry students learning about synthetic methodologies.

In summary, 1-(4-methoxybutylamino)-3-phenoxy-butan-2-ol stands out due to its potential applications in medicine, its structural complexity, and the promising avenues it opens for future research. As a student of chemistry, exploring compounds like this one can enhance your understanding of the intersections between structure and function in organic molecules.

Synonyms
SAS 514
7614-42-8
2-BUTANOL, 1-(4-METHOXYBUTYL)AMINO-3-PHENOXY-
DTXSID20997488
1-[(4-methoxybutyl)amino]-3-phenoxybutan-2-ol