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4-Methoxyacetophenone

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Identification
Molecular formula
C9H10O2
CAS number
100-06-1
IUPAC name
1-(4-methoxyphenyl)ethanone
State
State

At room temperature, 4-Methoxyacetophenone is typically a solid, existing as crystalline structures. It is stable under standard conditions.

Melting point (Celsius)
37.00
Melting point (Kelvin)
310.15
Boiling point (Celsius)
263.00
Boiling point (Kelvin)
536.15
General information
Molecular weight
150.17g/mol
Molar mass
150.1740g/mol
Density
1.0560g/cm3
Appearence

4-Methoxyacetophenone is a crystalline compound that typically appears as colorless or white crystals, often with a pleasant characteristic odor. It may also appear as a slightly yellowish solid depending on conditions.

Comment on solubility

Solubility of 1-(4-methoxyphenyl)ethanone

1-(4-methoxyphenyl)ethanone, also known as p-methoxyacetophenone, exhibits interesting solubility characteristics that are important for various applications in organic synthesis and medicinal chemistry.

Solubility Characteristics

  • Polar Solvents: This compound demonstrates moderate solubility in polar solvents such as methanol and ethanol, which is beneficial for reactions where polar solvents are required.
  • Non-Polar Solvents: It is more soluble in non-polar solvents like hexane and chloroform, indicating a strong hydrophobic character due to its aromatic structure.
  • Aqueous Solutions: 1-(4-methoxyphenyl)ethanone is not soluble in water, which can be attributed to the low polarity of the overall molecule.

Summary

In summary, the solubility of 1-(4-methoxyphenyl)ethanone is influenced by factors such as:

  1. The presence of the methoxy group, which increases its solubility in polar solvents relative to non-substituted ketones.
  2. The hydrophobic phenyl ring that facilitates better solubility in organic solvents.

Overall, understanding the solubility of this compound is essential for utilizing it effectively in various chemical processes.

Interesting facts

Interesting Facts about 1-(4-Methoxyphenyl)ethanone

1-(4-methoxyphenyl)ethanone, also known as p-methoxyacetophenone, is a fascinating organic compound that belongs to the family of ketones. This compound has garnered interest in various fields, especially in organic synthesis and fragrance chemistry. Here are some intriguing points about this chemical:

  • Versatile Precursor: 1-(4-methoxyphenyl)ethanone is often utilized as a starting material in the synthesis of other complex organic molecules.
  • Fragrance Applications: Its pleasant odor makes it a valuable component in the flavor and fragrance industry, often enhancing the scent profiles of perfumes and cosmetics.
  • Photophysical Properties: The compound exhibits unique photophysical properties, such as fluorescence, making it useful in certain photochemical applications.
  • Biological Activity: Research has shown that certain derivatives of 1-(4-methoxyphenyl)ethanone possess biological activities, potentially leading to the development of new pharmaceuticals.
  • Ubiquitous Presence: This compound can be found in various natural sources, particularly in essential oils, allowing for exploration in natural product chemistry.

As characterized by its functional group and aromatic ring, 1-(4-methoxyphenyl)ethanone is a prime example of how simple modifications to a structure can significantly alter its properties and applications. Chemistry enthusiasts would appreciate its role in synthetic pathways and its contribution to both industrial and academic research.

In the words of a renowned chemist, "The beauty of chemistry lies in its ability to turn abstract concepts into tangible results." This statement holds true for compounds like 1-(4-methoxyphenyl)ethanone that bridge theoretical knowledge and practical applications.

Synonyms
4'-Methoxyacetophenone
100-06-1
4-Methoxyacetophenone
4-Acetylanisole
1-(4-Methoxyphenyl)ethanone
p-Methoxyacetophenone
Acetanisole
Novatone
Ethanone, 1-(4-methoxyphenyl)-
Linarodin
1-(4-methoxyphenyl)ethan-1-one
Vananote
P-ACETYLANISOLE
4-Methoxyphenyl methyl ketone
Acetophenone, 4'-methoxy-
p-Methoxyphenyl methyl ketone
Methyl p-methoxyphenyl ketone
4-Methoxyacetofenon
p-methoxy acetophenone
Methyl 4-methoxyphenyl ketone
FEMA No. 2005
Anisyl, p-, methyl ketone
4-Methoxyacetofenon [Czech]
acetylanisole
4-Methoxy-acetophenone
NSC 209523
EINECS 202-815-9
UNII-0IRH2BR587
MFCD00008745
p-Metoxyacetophenone
0IRH2BR587
DTXSID2044347
CHEBI:86567
4-methoxy acetophenone
AI3-00227
para-Methoxyacetophenone
4'-methoxy-acetophenone
NSC-5601
Acetophenone, p-methoxy-
ACETANISOLE [FCC]
ACETANISOLE [FHFI]
NSC-209523
1-(4-methoxyphenyl)-ethanone
CHEMBL401912
DTXCID0024347
HSDB 8319
EC 202-815-9
1-(4-methoxyphenyl)ethanone-OCD3
Acetanisole (FCC)
4-Methoxyacetofenon (Czech)
WLN: 1VR DO1
4-METHOXYACETOPHENONE (D3)
1804943-43-8
pAcetylanisole
Bananote
4-Acetoanisole
4-Methoxyphenylacetone; Mebeverine Hydrochloride Imp. A (Pharmeuropa)
4Methoxyacetofenon
pMethoxyacetophenone
4methoxyacetophenone
p-methoxyactophenone
4'methoxyacetophenone
paramethoxyacetophenone
p -methoxyacetophenone
p-methoxy-acetophenone
Acetophenone, 4'methoxy
1(4Methoxyphenyl)ethanone
Anisyl, p, methyl ketone
bmse010024
Methyl pmethoxyphenyl ketone
pMethoxyphenyl methyl ketone
methyl 4methoxyphenyl ketone
4Methoxyphenyl methyl ketone
SCHEMBL41285
Ethanone, 1(4methoxyphenyl)
1-(4-methoxy-phenyl)ethanone
1-(4-methoxyphenyl) ethanone
4'-Methoxyacetophenone, 99%
1-(4-Methoxy-phenyl)-ethanone
1-(4-Methoxyphenyl)ethanone #
SCHEMBL12015229
FEMA 2005
1-[4-(methyloxy)phenyl]ethanone
NSC5601
Acetanisole, >=98%, FCC, FG
HY-Y0024
STR00157
Tox21_300687
BDBM50376209
NSC209523
STK498196
AKOS000119536
FM33959
PS-3395
Ethanone, 1-(4-methoxyphenyl)-(9CI)
NCGC00188270-01
NCGC00188270-02
NCGC00254595-01
AC-10916
CAS-100-06-1
4'-Methoxyacetophenone, analytical standard
DB-003499
CS-0008322
M0105
NS00006071
EN300-16104
D71251
4'-Methoxyacetophenone, purum, >=99.0% (GC)
AB-131/40174083
Q229995
doi:10.14272/NTPLXRHDUXRPNE-UHFFFAOYSA-N.2
Z53832960
F0001-0007
Flavor and Extract Manufacturers' Association No. 2005
202-815-9
4-Acetylanisole 4'-Methoxyacetophenone 1-(4-Methoxyphenyl)ethanone Acetanisole Novatone 4-Acetylanisole Linarodin Vananote Acetophenone, 4'-methoxy- Ethanone, 1-(4-methoxyphenyl)- p-Methoxyacetophenone
922-271-2
O9F