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Tolimidone

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Identification
Molecular formula
C10H12N2O2
CAS number
7259-37-8
IUPAC name
1-(4-methoxyphenyl)imidazolidin-2-one
State
State

At room temperature, Tolimidone is a solid.

Melting point (Celsius)
145.00
Melting point (Kelvin)
418.15
Boiling point (Celsius)
334.80
Boiling point (Kelvin)
607.95
General information
Molecular weight
192.22g/mol
Molar mass
192.2220g/mol
Density
1.2100g/cm3
Appearence

Tolimidone typically appears as white to off-white crystalline powder.

Comment on solubility

Solubility of 1-(4-methoxyphenyl)imidazolidin-2-one

1-(4-methoxyphenyl)imidazolidin-2-one, a compound with intriguing structural features, exhibits specific solubility characteristics that are important to note. The solubility of a compound can greatly influence its application in various fields such as pharmaceuticals, where the ease of dissolution is crucial for bioavailability.

General Solubility Context:

For 1-(4-methoxyphenyl)imidazolidin-2-one, its solubility can be affected by several factors, including:

  • Polarity: The presence of methoxy groups typically contributes to the polarity of the molecule, potentially enhancing its solubility in polar solvents.
  • Hydrogen Bonding: The amide group in the imidazolidinone structure allows for hydrogen bonding, which can facilitate solubility in water.
  • Solvent Interactions: Its solubility will vary significantly among different solvents, being more soluble in protic solvents compared to aprotic solvents.

In general, compounds of this nature may be categorized as:

  1. Soluble: In organic solvents like methanol and ethanol.
  2. Partially Soluble: In water, depending on the concentration and temperature.
  3. Insoluble: In non-polar solvents like hexane.

Overall, understanding the solubility of 1-(4-methoxyphenyl)imidazolidin-2-one is vital for its effective use in applications where dissolution is necessary. As the saying goes, "Solubility is the key to discovery," emphasizing its importance in the chemistry of this compound.

Interesting facts

Interesting Facts About 1-(4-methoxyphenyl)imidazolidin-2-one

1-(4-methoxyphenyl)imidazolidin-2-one is a fascinating compound with a variety of applications in the field of chemistry and medicinal sciences. Here are some intriguing facts about this compound:

  • Structural Significance: This compound features an imidazolidin-2-one core, which is a five-membered ring containing nitrogen atoms. Its unique structure contributes to its reactivity and versatility in various chemical reactions.
  • Pharmacological Potential: Research has suggested that derivatives of imidazolidin-2-one may possess significant biological activity. Compounds related to this structure can exhibit antibacterial, antiviral, and anticancer properties, making it an interesting target for drug development.
  • Substituent Influence: The 4-methoxyphenyl group attached to the imidazolidin-2-one can greatly influence the compound's physical and chemical properties. The methoxy group acts as an electron-donating substituent, which can enhance the compound's reactivity and interaction with biological systems.
  • Research Applications: Scientists are increasingly interested in imidazolidinone derivatives for use in synthetic chemistry and materials science. Their ability to undergo transformations and serve as building blocks for more complex molecules opens doors for innovative research.
  • Known Analogues: There are numerous analogues of imidazolidin-2-one found in nature and synthesized in the laboratory. These analogues often display varying efficacy in biological assays, showcasing the importance of structural modifications.

In summary, 1-(4-methoxyphenyl)imidazolidin-2-one is not just a chemical compound; it represents a platform for further innovation in drug design and synthetic methods. Its balance of structural uniqueness and biological potential truly encapsulates the essence of modern chemistry.

Synonyms
BRN 0648267
2-IMIDAZOLIDINONE, 1-(p-METHOXYPHENYL)-
1-(p-Methoxyphenyl)-2-imidazolidinone
DTXSID20163247
5-24-01-00103 (Beilstein Handbook Reference)
DTXCID1085738
14599-72-5
62868-39-7
1-(4-methoxyphenyl)imidazolidin-2-one
1-(4-Methoxyphenyl)tetrahydro-2H-imidazol-2-one
MFCD01720969
2-Imidazolidinone,1-(4-methoxyphenyl)-
1-(4-methoxyphenyl)-2-imidazolidinone
SCHEMBL2884739
FNWSPWKYYZASIN-UHFFFAOYSA-N
SBB091430
1-(4-methoxyphenyl)imidazolin-2-one
AKOS005072711
1-(3-Methoxyphenyl)-2-imidazolidinone
FA-0844
CS-0326799